184370

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ygfYX/Cpta(toxin)
Location 1264737..1265406 Replicon chromosome
Accession NZ_CP066369
Organism Shewanella putrefaciens strain CGMCC-1.6515

Toxin (Protein)


Gene name ygfX Uniprot ID -
Locus tag JFT56_RS05475 Protein ID WP_198782687.1
Coordinates 1264966..1265406 (+) Length 147 a.a.

Antitoxin (Protein)


Gene name ygfY Uniprot ID -
Locus tag JFT56_RS05470 Protein ID WP_198782686.1
Coordinates 1264737..1264985 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JFT56_RS05445 1260392..1261198 + 807 WP_198782681.1 prolipoprotein diacylglyceryl transferase -
JFT56_RS05450 1261198..1261992 + 795 WP_198782682.1 thymidylate synthase -
JFT56_RS05455 1262110..1263279 + 1170 WP_198782683.1 Na+/H+ antiporter NhaA -
JFT56_RS05460 1263282..1263668 + 387 WP_198782684.1 hypothetical protein -
JFT56_RS05465 1263744..1264652 + 909 WP_198782685.1 transcriptional activator NhaR -
JFT56_RS05470 1264737..1264985 + 249 WP_198782686.1 succinate dehydrogenase assembly factor 2 Antitoxin
JFT56_RS05475 1264966..1265406 + 441 WP_198782687.1 hypothetical protein Toxin
JFT56_RS05480 1265428..1267041 - 1614 WP_198782688.1 L-aspartate oxidase -
JFT56_RS05485 1267231..1267809 + 579 WP_198782689.1 RNA polymerase sigma factor RpoE -
JFT56_RS05490 1267852..1268496 + 645 WP_198782690.1 anti-sigma factor -
JFT56_RS05495 1268509..1269441 + 933 WP_198782691.1 MucB/RseB C-terminal domain-containing protein -
JFT56_RS05500 1269453..1269926 + 474 WP_198782692.1 SoxR reducing system RseC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(6-135)

Antitoxin

Flavinator of succinate dehydrogenase

(7-78)


Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 17155.20 Da        Isoelectric Point: 8.8758

>T184370 WP_198782687.1 NZ_CP066369:1264966-1265406 [Shewanella putrefaciens]
VEERHHSFSVKVSFDQRLSLVVFMSICLSSLLAWPQTESFGVFLLKLAVISLIVCFLLYQLWRLKDWQFSFVLNRNGEGR
LASGEHFQVLRRTWVTPFVCLMYLDIDTKPRLLPLWADMFTDADYRHLCRLLLNAKTLQAKSRTEI

Download         Length: 441 bp

>T184370 NZ_CP087629:c4854569-4854285 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACCTATGAACTGGAGTTTGATCCACGAGCCTGGCGCGAATGGCAGAAGCCTGGCGAGACGGTCAAAAAACAGTTCAA
AAATAAGCTCCAGCAGATTGTGCAGAATCCGCGAATTGAGTCGGCCAGGCTGAGCGATTTACCGGATTGCTACAAAATCA
AGCTTAAGGCGTCAGGTTATCGGTTGGTGTATCAAGTACGAGATAGTGTGGTGGTGGTTTACGTTATTGCCATTGGCAAA
AGAGAGAAAGCGGCCGTTTATCATCAGGCGAATAAACGGCTCTAA

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9626.22 Da        Isoelectric Point: 4.6510

>AT184370 WP_198782686.1 NZ_CP066369:1264737-1264985 [Shewanella putrefaciens]
MELMNIARVRWACRRGMLELDVLFQPFVEHVYQELSDEDKAVFIRLLECEDPELFAWFMGHETCPDAELARMVVKVRGRA
AP

Download         Length: 249 bp

>AT184370 NZ_CP087629:c4854801-4854559 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGCCACGCTCAATGTTCGACTGGACGATAAACTCAAAAAAGAGGCTTATGCCGTGCTGGAGAAACTCGATATGACACC
AACGGAGGCGGTACGCCTGCTGTTTCAATACATTGCGGAAAATGGCCGCATGCCGGTGAAAAGTATGACCATCAGTGATG
GCGAAGCGGCGTTATTACGCACCGTTCGCGAACGGCTGGAAAACCCACGGCCGGGGGTTAAGGTGAGTCTGGATGACCTA
TGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References