Detailed information of TA system TA184368

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /GNAT-DUF1778
• Location: 302291..303057
• Replicon: chromosome
• Accession: NZ_CP066369
• Organism: Shewanella putrefaciens strain CGMCC-1.6515

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JFT56_RS01390
• Protein ID: WP_198783470.1
• Coordinates: 302291..302788 (-)
• Length: 166 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: JFT56_RS01395
• Protein ID: WP_198781964.1
• Coordinates: 302785..303057 (-)
• Length: 91 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JFT56_RS01370	297972..298814	+	843	WP_007651514.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-
JFT56_RS01380	299983..300831	+	849	WP_198781963.1	FRG domain-containing protein	-
JFT56_RS01390	302291..302788	-	498	WP_198783470.1	GNAT family N-acetyltransferase	Toxin
JFT56_RS01395	302785..303057	-	273	WP_198781964.1	DUF1778 domain-containing protein	Antitoxin
JFT56_RS01400	303162..304817	-	1656	WP_198781965.1	hypothetical protein	-
JFT56_RS01405	304998..306218	-	1221	WP_198781966.1	threonine/serine exporter family protein	-
JFT56_RS01410	306376..306774	+	399	WP_198781967.1	MAPEG family protein	-
JFT56_RS01415	306769..307002	-	234	WP_198781968.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• GNAT domain (86-149)

Antitoxin

• Vibrio phage ICP1, Orf50 (7-85)

Sequences

Toxin

Protein

• Length: 166 a.a.
• Molecular weight: 18577.18 Da
• Isoelectric Point: 9.3036

>T184368 WP_198783470.1 NZ_CP066369:c302788-302291 [Shewanella putrefaciens]
IMNTVLLDKDKHDRNRFNCGTDALNNYFKVMASQQAKKDNTRTFVLEDDNNNAHIIGFYTLTMTPIDLKALPEKLQKKHQ
SSTSGGLIARLAVDDRYKGKGFGEWLLIDALRKLLAASDSVAFPFVIVDAKDGAKHFYERYGFQAFQNAENKLFVTIADI
RASLG

Nucleotide

• Length: 498 bp

>T184368 NZ_CP087629:4138703-4138921 [Klebsiella pneumoniae subsp. pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACTTCTGTCTGGAAATTTATCCGCTAA

Antitoxin

Protein

• Length: 91 a.a.
• Molecular weight: 9913.53 Da
• Isoelectric Point: 9.7672

>AT184368 WP_198781964.1 NZ_CP066369:c303057-302785 [Shewanella putrefaciens]
MATTLPRITARVDVDTQDLLTKAAALAGMSSINSFVLNAAIEKAKQVIEREQTLKLNQADAVLLMEALDKPTVVNTKLKL
ASERYERKTQ

Nucleotide

• Length: 273 bp

>AT184368 NZ_CP087629:4138302-4138676 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGACGAATACTCGCCAAAAAGACATGATATTGCACAGCTACGCTTTCTCTGCGAAACGCTGTATCATGACTGCCTTGC
AAACCTGGAAGAGAGCAACCATGGCTGGGTCAACGACCCGACGTCGGCTGTCAATCTCCAGTTAAATGAATTGATCGAGC
ACATTGCCACATTCGCTCTTAATTATAAAATTAAGTATGCAGAGGATAATAAGCTGATCGCTCAGGTTGACGAATATCTG
GACGACACTTTTACGTTGTTCAGTAACTACGGCATTAACTCTACGGATTTGCAAAAGTGGAAAAAATCCGGTAACCGACT
ATTTCGTTGCTTTGTCAACGCCAGCCGGGAAAACCCGGCCAGTCTATCGTGTTAG