184367

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ParE-CopA/ParE-RHH
Location 199959..200524 Replicon chromosome
Accession NZ_CP066369
Organism Shewanella putrefaciens strain CGMCC-1.6515

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag JFT56_RS00845 Protein ID WP_198781908.1
Coordinates 200231..200524 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name copA Uniprot ID -
Locus tag JFT56_RS00840 Protein ID WP_198781907.1
Coordinates 199959..200243 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JFT56_RS00805 195809..196006 - 198 WP_037459496.1 AlpA family transcriptional regulator -
JFT56_RS00810 196154..196630 + 477 WP_198783467.1 DNA repair protein RadC -
JFT56_RS00815 196671..197033 + 363 WP_011920075.1 hypothetical protein -
JFT56_RS00820 197176..197556 + 381 WP_198781903.1 type IV toxin-antitoxin system YeeU family antitoxin -
JFT56_RS00825 197701..198114 + 414 WP_198781904.1 DUF2787 domain-containing protein -
JFT56_RS00830 198237..198797 + 561 WP_198781905.1 tyrosine-type recombinase/integrase -
JFT56_RS00835 198945..199667 + 723 WP_198781906.1 lecithin retinol acyltransferase family protein -
JFT56_RS00840 199959..200243 + 285 WP_198781907.1 CopG family ribbon-helix-helix protein Antitoxin
JFT56_RS00845 200231..200524 + 294 WP_198781908.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
JFT56_RS00850 200652..201320 - 669 WP_198781909.1 inovirus Gp2 family protein -
JFT56_RS00855 201636..203069 - 1434 WP_198781910.1 hypothetical protein -
JFT56_RS00860 203237..205174 + 1938 WP_198781911.1 transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-95)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11167.73 Da        Isoelectric Point: 5.8404

>T184367 WP_198781908.1 NZ_CP066369:200231-200524 [Shewanella putrefaciens]
MPQIIFTATALRDLERLREFLRSKNPPAVQRAASAIINTIRKLESYPDIGRPIDDNDFSFRELLIDFGDTGYLAMYQYDG
GERLTVLCIRHQKEAGY

Download         Length: 294 bp

>T184367 NZ_CP087629:c2714614-2713292 [Klebsiella pneumoniae subsp. pneumoniae]
ATGGCGACGCTTACCACCTGGATGAACAATGTGCGCGTGGGAACCTTAACCCGCCAGGCTAACGGGGCGCACAGTTTTCG
CTATGACGAAGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCACTGCCGCTGCAGTATGGCAATATCACTG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGACCGGATCGTCAGGCGCTATCAG
GCGCGCTCGAAGCAGCCGTTCGATCTGCTGGCCGAAGTCGGGCGGGATAGCGTAGGGGCGGTGACCCTCCTGCCGCCGGG
GGAAGAGGCGCACCTGGAAGGATTACGCTGGCAGACGCTGGACGAGGCGCAGCTCACCGCTTTGCTGACCGCTTACCAGT
CGGATATCCCCCTCGGGATGATTACCAGCCAGGACGATTTCCGTATCTCGGTGGCCGGCGCCCAGGAGAAAACGGCGCTG
CTGCGGATGGGCGAGCAGTGGTGTATTCCGCAGGGCGCCACGCCGACCACGCATATCATTAAGCTGCCCATCGGCGAGAT
CAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAATGAGTATCTGTGCCTGGCGCTGGCCAGAGAACTGG
GCCTGGCGGTGCCGGAAGCGGAGATCATCACCACCCCGCGGATCCGCGCCCTGGCGGTAACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGACGGGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCTTTTGGTCTTCCTTCAGCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCGAGTGAAGCGCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTCTTCCAGTGGCTGACGGGGGCGACGGACGGTCACGCAAAAAACTTCTCAATTTACCTGTTG
CCCGGCGGCAGCTACCGCTTAACACCGTTCTACGACATTATTTCGGCGTTTCCGGTGCTGGGCGGCACGGGACTGCATCT
GCGCGATCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGTAAAACAGAGATTAACGCCATCTATCCGCGTCATT
TTCTGGCGACGGCCAAAGCGGTGAACTTTCCCCTGGAGCAGATGCTGGCGATCCTCCAGGAGTTTGCCGGGCATGTGCCG
CAGGCAATCGAAAGCGCTCGCCGGACGCTGCCGGCGGACTTTTCCAGCCACGTCTGGCAGGCCATTACAGAGAACATGCT
GAAGCTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGCTATAG

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10971.29 Da        Isoelectric Point: 6.3342

>AT184367 WP_198781907.1 NZ_CP066369:199959-200243 [Shewanella putrefaciens]
MSTIKPVSVKLDADIKARVEHLAETRKRSSHWMMREAIREYVEREEKREALQQEALRAWEEHQTSGLHVTGDEVVSWLES
WGSENEKASPTCHK

Download         Length: 285 bp

>AT184367 NZ_CP087629:c2714880-2714614 [Klebsiella pneumoniae subsp. pneumoniae]
ATGAATTCCCCGCAGATATACAGTCCCGTGCAGCTGGCCAATTACCTGAAGCTGCTGCGCCAGCAGAACCACTGGACCCA
GGATGCGCTGGCCAGGCGGATCGGCATTAAGCAGGCCACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACGCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACGCTGAACGCCAAAGCTGCTGAGACGGCGCCGGCTCCC
GATAACAACACGGACCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References