Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) EcnAB/-
Location 4886510..4886871 Replicon chromosome
Accession NZ_CP066343
Organism Xanthomonas citri pv. durantae strain LMG696

Toxin (Protein)


Gene name EcnB Uniprot ID M4UGA1
Locus tag Xdur_RS21310 Protein ID WP_005914328.1
Coordinates 4886510..4886644 (-) Length 45 a.a.

Antitoxin (Protein)


Gene name EcnA Uniprot ID H8FG64
Locus tag Xdur_RS21315 Protein ID WP_003486606.1
Coordinates 4886719..4886871 (-) Length 51 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
Xdur_RS21290 (Xdur_021245) 4881648..4883339 - 1692 WP_015471463.1 M28 family metallopeptidase -
Xdur_RS21295 (Xdur_021250) 4883531..4884475 - 945 WP_015463704.1 MBL fold metallo-hydrolase -
Xdur_RS21300 (Xdur_021255) 4884604..4885893 - 1290 WP_015463705.1 tryptophan--tRNA ligase -
Xdur_RS21305 (Xdur_021260) 4886074..4886283 - 210 Protein_4173 CsbD family protein -
Xdur_RS21310 (Xdur_021265) 4886510..4886644 - 135 WP_005914328.1 entericidin A/B family lipoprotein Toxin
Xdur_RS21315 (Xdur_021270) 4886719..4886871 - 153 WP_003486606.1 entericidin A/B family lipoprotein Antitoxin
Xdur_RS21320 (Xdur_021275) 4886978..4887901 - 924 WP_040277282.1 arginase -
Xdur_RS21325 (Xdur_021280) 4888222..4888674 + 453 WP_003486611.1 roadblock/LC7 domain-containing protein -
Xdur_RS21330 (Xdur_021285) 4888738..4889097 + 360 WP_003486613.1 hypothetical protein -
Xdur_RS21335 (Xdur_021290) 4889194..4890111 + 918 WP_011052673.1 hypothetical protein -
Xdur_RS21340 (Xdur_021295) 4890108..4890650 + 543 WP_003486615.1 GTPase -
Xdur_RS21345 (Xdur_021300) 4891088..4891771 + 684 WP_011052674.1 dTMP kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Entericidin A/B

(23-42)

Antitoxin

Entericidin A/B

(23-42)


Sequences

Toxin        


Download         Length: 45 a.a.        Molecular weight: 4459.32 Da        Isoelectric Point: 9.3487

>T184304 WP_005914328.1 NZ_CP066343:c4886644-4886510 [Xanthomonas citri pv. durantae]
MKRAIVLLVLSMLSVGMLAGCNTVAGAGKDVQGAGEKVEDAARK

Download         Length: 135 bp

>T184304 NZ_CP087608:168144-168293 [Klebsiella pneumoniae subsp. pneumoniae]
ATGACGAAATATGCCCTTATCGGGTTGCTCGCCGTGTGTGCCACGGTATTGTGTTTTTCACTGATATTCAGGGAACGGTT
ATGTGAACTGAATATTCACAGGGGAAATACAGTGGTGCAGGTAACTCTGGCCTACGAAGCACGGAAGTAA

Antitoxin


Download         Length: 51 a.a.        Molecular weight: 5122.07 Da        Isoelectric Point: 8.7942

>AT184304 WP_003486606.1 NZ_CP066343:c4886871-4886719 [Xanthomonas citri pv. durantae]
MKRLLTLMVLGLFSAGVMTGCNTVAGAGKDMQGAGNKVEKTAEKCSDGKC

Download         Length: 153 bp

>AT184304 NZ_CP087608:c168099-168040 [Klebsiella pneumoniae subsp. pneumoniae]
TAAGTACTTCATGCAGACCTCACGAGTTAATGGATTAACGAGTGGGGTCTTCGCATTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3G2W7U6

Antitoxin

Source ID Structure
AlphaFold DB A0A828YLX6

References