Detailed information of TA system TA184302

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/PIN-MazE
• Location: 2608414..2609047
• Replicon: chromosome
• Accession: NZ_CP066343
• Organism: Xanthomonas citri pv. durantae strain LMG696

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: Xdur_RS11490
• Protein ID: WP_015463212.1
• Coordinates: 2608414..2608827 (-)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: M4TWF0
• Locus tag: Xdur_RS11495
• Protein ID: WP_015463213.1
• Coordinates: 2608814..2609047 (-)
• Length: 78 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
Xdur_RS11475 (Xdur_011440)	2604427..2606286	+	1860	WP_234351584.1	TonB-dependent siderophore receptor	-
Xdur_RS11480 (Xdur_011445)	2606495..2608009	+	1515	WP_015463210.1	conjugal transfer protein TraG N-terminal domain-containing protein	-
Xdur_RS11485 (Xdur_011450)	2608025..2608387	-	363	WP_015463211.1	DUF3742 family protein	-
Xdur_RS11490 (Xdur_011455)	2608414..2608827	-	414	WP_015463212.1	PIN domain-containing protein	Toxin
Xdur_RS11495 (Xdur_011460)	2608814..2609047	-	234	WP_015463213.1	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	Antitoxin
Xdur_RS11500 (Xdur_011465)	2609329..2610336	+	1008	WP_015463214.1	DUF4917 family protein	-
Xdur_RS11505 (Xdur_011470)	2610469..2610924	-	456	WP_015463215.1	hypothetical protein	-
Xdur_RS11510 (Xdur_011475)	2611319..2611894	+	576	WP_011051400.1	sigma-70 family RNA polymerase sigma factor	-
Xdur_RS11515 (Xdur_011480)	2611875..2612924	+	1050	WP_015472205.1	FecR domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (8-119)

Antitoxin

• SpoVT-AbrB domain (5-45)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 15221.65 Da
• Isoelectric Point: 6.3225

>T184302 WP_015463212.1 NZ_CP066343:c2608827-2608414 [Xanthomonas citri pv. durantae]
MAAGKGKVFLDSNVVLYLLSEDAVKADGAEALLQRRPVISVQVLNEVTHVCVRKLKMGWDEVGQFLALVRSFCKIVPLTV
DVHDRARQLAERHQLSFYDACIVAAAAIEGCQTLYSEDMHHGLIIEESLSIRNPFNV

Nucleotide

• Length: 414 bp

>T184302 NZ_CP087607:49658-49969 [Klebsiella pneumoniae subsp. pneumoniae]
ATGCACATTGTATCGAGAGCACCTTTCGATACAGCCACCAGGCAATTCCCCAATCAGGCAGCGGCACTAGACGACGTATA
CCGGACTTTGAAGAGAGAGAACTACACTTCACCGGACGAAATGAAAAAACGATTTGCCTCGCTGGACAGAATGAAATATC
GGGAGAAGTGGTGGGTGATCGATGTTGGCGGTGGGAATTTAAGGGTGATGTTTTTTGCTGATTTTGAACGTGGGAAAATC
TTTATAAAGCACATAACCACACACGCCGAATACGACAAGCTGACAGATTTTTACCGGAGAACTAAAGAATGA

Antitoxin

Protein

• Length: 78 a.a.
• Molecular weight: 8663.97 Da
• Isoelectric Point: 8.7848

>AT184302 WP_015463213.1 NZ_CP066343:c2609047-2608814 [Xanthomonas citri pv. durantae]
MQVAKWGNSLAVRLPSSLVEALELREGDDIEIVVDDPRLFAVRKKPGPEAMLERLRAFRGKLPADFKFNRDEANGRG

Nucleotide

• Length: 234 bp

>AT184302 NZ_CP087607:49966-50385 [Klebsiella pneumoniae subsp. pneumoniae]
ATGATGTACACCGATGCTATCCAGGCGGCAAACAGCCTGGTTAGCATTGTCCCCCTCCTGGGGGGCAATGCCTCTCGCAA
GGACTATGAAGACGCGCTGACGCTGGTTGAATACCTGGTTGAACACGAGCCAGATCATCCGCTGGTGGACATGCTGGTTG
CGAAAATTGCCCAGTATGAAGATGAGGCGGAAGAGTTCGCAGAGTTCAACGACCGTATTGCAGCGTTACCAAGTGGCGTG
GCCCTGCTGCGTGTCCTGATGGACCAGCACAAACTGACTCAGAGTGATTTTGAGGAAGAGATTGGTAAGAAATCGCTGGT
GAGCCGCATCCTTAACGGGACTCGCTCACTAACACTAGATCACATGAAAGCACTTGCGCGGCGCTTCAACATTCCGCCCA
GCTCATTCATGGACGCGTAA

Structures

Antitoxin

• AlphaFold DB: M4TWF0