Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2870433..2870949 Replicon chromosome
Accession NZ_CP066310
Organism Azotobacter chroococcum strain HR1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag GKQ51_RS13420 Protein ID WP_131254396.1
Coordinates 2870668..2870949 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag GKQ51_RS13415 Protein ID WP_198866264.1
Coordinates 2870433..2870678 (+) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GKQ51_RS13395 2867210..2867545 - 336 WP_198866260.1 hypothetical protein -
GKQ51_RS13400 2867577..2867864 - 288 WP_198866261.1 hypothetical protein -
GKQ51_RS13405 2868076..2869269 - 1194 WP_198866262.1 IS4 family transposase -
GKQ51_RS13410 2869474..2870244 + 771 WP_198866263.1 NERD domain-containing protein -
GKQ51_RS13415 2870433..2870678 + 246 WP_198866264.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
GKQ51_RS13420 2870668..2870949 + 282 WP_131254396.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
GKQ51_RS13425 2871011..2871403 - 393 WP_198866265.1 hypothetical protein -
GKQ51_RS13430 2871404..2874682 - 3279 WP_198866266.1 tape measure protein -
GKQ51_RS13435 2874826..2875131 - 306 WP_089168479.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2862749..2888701 25952


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-71)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10908.81 Da        Isoelectric Point: 10.5773

>T184283 WP_131254396.1 NZ_CP066310:2870668-2870949 [Azotobacter chroococcum]
MTYSLEFLPSALKEWEKLGHTVREQLKKKLRERLELPKVPADALREMPNHYKIKLRASGYRLVYRVEDERVVVVVVAVGK
RERSAAYEKAKGR

Download         Length: 282 bp

>T184283 NZ_CP087593:c2565698-2565591 [Staphylococcus aureus]
ATGTTCAATTTATTAATTAACATCATGACTTCAGCTATAAGCGGCTGTCTTGTTGCGTTTTTTGCACATTGGTTACGAAC
GCGCAACAATAAAAAAGGTGACAAATAA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8615.86 Da        Isoelectric Point: 4.4963

>AT184283 WP_198866264.1 NZ_CP066310:2870433-2870678 [Azotobacter chroococcum]
MQNVLANKAVSVSELKKNPSAVIGSANGGPVAVLNHNRVMGYMVPAEAFEAMVERLEDLELAELARSRAGETPVPVNLDD
L

Download         Length: 246 bp

>AT184283 NZ_CP087593:2565514-2565574 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References