Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /RES-TIGR02293
Location 2122207..2123090 Replicon chromosome
Accession NZ_CP066310
Organism Azotobacter chroococcum strain HR1

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag GKQ51_RS10075 Protein ID WP_198867877.1
Coordinates 2122207..2122644 (-) Length 146 a.a.

Antitoxin (Protein)


Gene name PrcA Uniprot ID -
Locus tag GKQ51_RS10080 Protein ID WP_198867878.1
Coordinates 2122641..2123090 (-) Length 150 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GKQ51_RS10050 2117961..2118506 + 546 WP_198867874.1 hypothetical protein -
GKQ51_RS10055 2118503..2118937 + 435 WP_198867875.1 flagellar protein FlhE -
GKQ51_RS10060 2119121..2119816 + 696 WP_089168037.1 RNA polymerase sigma factor FliA -
GKQ51_RS10065 2119895..2121583 + 1689 WP_198867876.1 PilZ domain-containing protein -
GKQ51_RS10070 2121618..2121988 - 371 Protein_1963 flagellar protein FlaG -
GKQ51_RS10075 2122207..2122644 - 438 WP_198867877.1 RES family NAD+ phosphorylase Toxin
GKQ51_RS10080 2122641..2123090 - 450 WP_198867878.1 DUF2384 domain-containing protein Antitoxin
GKQ51_RS10085 2123375..2123598 - 224 Protein_1966 hypothetical protein -
GKQ51_RS10090 2123714..2125027 - 1314 WP_198868022.1 IS4 family transposase -
GKQ51_RS10095 2125279..2125602 - 324 WP_198867879.1 hypothetical protein -
GKQ51_RS10100 2125802..2127124 + 1323 WP_198867880.1 UDP-glucose/GDP-mannose dehydrogenase family protein -
GKQ51_RS10105 2127159..2127929 + 771 WP_198867881.1 glucose-1-phosphate cytidylyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 2123714..2125078 1364


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

RES domain

(3-140)

Antitoxin

Antitoxin Xre

(29-146)


Sequences

Toxin        


Download         Length: 146 a.a.        Molecular weight: 15882.26 Da        Isoelectric Point: 4.8886

>T184282 WP_198867877.1 NZ_CP066310:c2122644-2122207 [Azotobacter chroococcum]
VILWRISAYADLGGIGGLRASGRWHHLGRPVVYAADSPAGAMLEVLVHLEIDPEDFPTTLQLIRIELPDPVSLAELPPLP
EHWKSDQEVTRAMGDHFLDGRSALLLPVPSAIIPCTTNYLFNPAHPEANGASIQVEKFPLDPRLL

Download         Length: 438 bp

>T184282 NZ_CP087593:c2540428-2540162 [Staphylococcus aureus]
ATGGCTAGGTTAAATATTACGTTTTCGCCTCAAGCCTTTGAAGATTATAAGTATTTTCAGCAGAACGATAAAAAAATGGT
GAAGAAGATTAATGAGTTACTTAAAAGTATTGACAGAAATGGTGCATTGGAAGGTATAGGTAAGCCTGAAAAGTTAAAAT
CGAATCTGACTGGGTATTATAGTAGACGTATCAATCACGAACATAGATTGGTTTATACAGTAGATGACAATCATATAAAA
ATAGCATCATGTAAATACCATTATTAA

Antitoxin


Download         Length: 150 a.a.        Molecular weight: 17037.64 Da        Isoelectric Point: 6.7345

>AT184282 WP_198867878.1 NZ_CP066310:c2123090-2122641 [Azotobacter chroococcum]
MLAEVLRDHGYTAYRARLQNLLDIPESATDFEIHTRITKGFPAARLMQLTEAGVVTPLERDQIIPLRTLKTRIERDQPLS
VEESDRFFRAAHITAMAEAVFGDREKARRWLSKPKERFSGLTPMQMLTTQQGTSQVEEMLLQIIEGLAL

Download         Length: 450 bp

>AT184282 NZ_CP087593:c2540679-2540428 [Staphylococcus aureus]
ATGATTATTAAAAATTATTCATACGCTCGACAGAATTTAAAGGCACTTATGACAAAAGTAAATGATGATAGTGATATGGT
AACTGTAACATCTACTGATGATAAAAACGTAGTAATCATGTCAGAATCAGATTATAACTCCATGATGGAAACACTTTACC
TCCAACAGAACCCAAATAATGCTGAACACTTAGCTCAATCAATTGCAGATCTAGAACGTGGGAAAACTATAACGAAAGAT
ATAGATGTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References