Detailed information of TA system TA184265

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): parDE/CC2985(antitoxin)
• Location: 327441..327988
• Replicon: plasmid unnamed1
• Accession: NZ_CP066273
• Organism: Agrobacterium tumefaciens strain FDAARGOS_1048

Toxin (Protein)

• Gene name: parE
• Uniprot ID: -
• Locus tag: I6I05_RS01515
• Protein ID: WP_038496495.1
• Coordinates: 327695..327988 (+)
• Length: 98 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: A0A7U5CZ68
• Locus tag: I6I05_RS01510
• Protein ID: WP_003519100.1
• Coordinates: 327441..327695 (+)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6I05_RS01495	322954..324714	+	1761	WP_038496489.1	penicillin-binding protein 2	-
I6I05_RS01500	324708..325328	-	621	WP_075807885.1	TetR/AcrR family transcriptional regulator	-
I6I05_RS01505	325940..327105	-	1166	Protein_300	IS110 family transposase	-
I6I05_RS01510	327441..327695	+	255	WP_003519100.1	type II toxin-antitoxin system ParD family antitoxin	Antitoxin
I6I05_RS01515	327695..327988	+	294	WP_038496495.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
I6I05_RS01520	328410..329779	+	1370	Protein_303	transposase	-
I6I05_RS01525	330133..331032	+	900	WP_046205651.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..815865	815865

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-148)

Antitoxin

• Antitoxin Xre-like, helix-turn-helix domain (38-95)

Sequences

Toxin

Protein

• Length: 98 a.a.
• Molecular weight: 12579.08 Da
• Isoelectric Point: 12.7867

>T184265 WP_038496495.1 NZ_CP066273:327695-327988 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 294 bp

>T184265 NZ_CP087584:2380414-2380875 [Providencia rettgeri]
ATGATTTTATATCGTTTGATTAAATCTGACTTTGCTCATGATGCGTGGTCCGGTCAAGGTGCTAGGTTATACGGTGGGCG
CTGGAACCATAAAGGTACGCCCGCTATCTACACATCAACAAGTATTTCATTAGCTGCTTTAGAAATTCTCGTTCATATAA
ACCAAGATACCGTGCTTAATCATTTCACTTTATTATCAATTGAGATCAACGATAGGTATGTGATGAAGCTGTCAGTAGAG
CATCTCCCTGATGATTGGCAGCGTGACCCAGCACCTACCTCCACAATGGACATAGGCACAACCTGGTTAACGAACCAAGA
CAGCCTAGCCTTAATTGTCCCTTCTTGTATTATTCCTTATGAATACAATGCCATTATTAACCCTATGCACCCGCAATTTC
AAAAAGTGACCCAAACCATTAAGCCCCTCGACTTTGCTTTTGACCCACGATTTAACCGGTAG

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 10912.81 Da
• Isoelectric Point: 12.7242

>AT184265 WP_003519100.1 NZ_CP066273:327441-327695 [Agrobacterium tumefaciens]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKK

Nucleotide

• Length: 255 bp

>AT184265 NZ_CP087584:2379956-2380417 [Providencia rettgeri]
ATGAGAAACTATATTCCAGCACTCCCAACCCAACCCGCCACGCCACCTTTTAAGCCCCTATGGCGCTTTGCTGGCCTACC
CGCAGAACGTGGTATCGAACTCACTCATTTCCTACGACAAGGTCTTTCCGTTACGGTGTTAGACAACATTCAAGAATGGT
CTGGCATCAGCAAATCTGAATTACTCCGTATTTCAGGTATTAATGAGCGCAATGTGGCAAGGCGTAGAAATGCAGGTCAG
CCACTCAATGCCGATGAAAGTGAAAGAATTGCTCGCTTAGTGCGTGTATTTGATGCCGCTGTACGCTTATTCAATGGTGA
TAAGTCAATGGCAAGTGATTGGTTGAATCACCCCGTGAAAGGCTTAGGACATACGCGCCCTATAGAGTTGATTGCCACTG
AAAGTGGTGCTCTTGAAGTTATCGACCTTATTGGCCGCATTGAACACGGTGTTTTTTCATGA

Structures

Antitoxin

• AlphaFold DB: A0A7U5CZ68