Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 211511..212142 Replicon plasmid unnamed1
Accession NZ_CP066273
Organism Agrobacterium tumefaciens strain FDAARGOS_1048

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I6I05_RS00925 Protein ID WP_038496209.1
Coordinates 211511..211912 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I6I05_RS00930 Protein ID WP_003519381.1
Coordinates 211912..212142 (-) Length 77 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I05_RS00900 206613..207896 + 1284 WP_025591772.1 plasmid partitioning protein RepA -
I6I05_RS00905 207893..208918 + 1026 WP_038496201.1 plasmid partitioning protein RepB -
I6I05_RS00910 209121..210335 + 1215 WP_038496203.1 replication initiation protein RepC -
I6I05_RS00915 210545..210838 - 294 WP_038496206.1 type II toxin-antitoxin system RelB/DinJ family antitoxin -
I6I05_RS00920 211217..211435 + 219 WP_038497375.1 BrnA antitoxin family protein -
I6I05_RS00925 211511..211912 - 402 WP_038496209.1 tRNA(fMet)-specific endonuclease VapC Toxin
I6I05_RS00930 211912..212142 - 231 WP_003519381.1 antitoxin Antitoxin
I6I05_RS00935 212927..213067 - 141 WP_003518781.1 hypothetical protein -
I6I05_RS00940 213438..214208 - 771 WP_038496212.1 4-hydroxy-2-oxoheptanedioate aldolase -
I6I05_RS00945 214216..214998 - 783 WP_038496215.1 2-oxo-hepta-3-ene-1,7-dioic acid hydratase -
I6I05_RS00950 215018..215911 - 894 WP_038496218.1 intradiol ring-cleavage dioxygenase -
I6I05_RS00955 216157..216891 + 735 WP_038496221.1 GntR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..815865 815865


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-133)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 19739.68 Da        Isoelectric Point: 5.5500

>T184264 WP_038496209.1 NZ_CP066273:c211912-211511 [Agrobacterium tumefaciens]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 402 bp

>T184264 NZ_CP087584:1512823-1513233 [Providencia rettgeri]
GTGGTCCTGTGGAAATCTAATCTTTCCATTTCATGGAAAACACAGTTTTTTTCAACCTGTGTTCATGGGGCAGTAGGCAT
GTTTTTGCTTGTTGCACCATGGGCACCGGCTCATTCAATGATATGGTTGCCACTTCTTGCGGTTGTGGTGGCTAGTTGGG
CAAAAAGCCAAAAGAACATCAGCAAAATAAAAGGGGTTGCTGTGTTGGTTAATGGTAATAAAGTCCAATGGAAAAAGAAT
GAATGGAATATTGTGAAAGCACCTTGGTTGAGCCGCTATGGCATCTTATTGTCATTAGAAGCTTTACAAGGTAAGCAACA
AAAAATTCACCTATGGGTTGCTAAAGACTCTGTTTCTGAGGAAAGTTGGCGTAATTTGAACCAATTATTACTTCAATACC
CTGATATTTAA

Antitoxin


Download         Length: 77 a.a.        Molecular weight: 11350.61 Da        Isoelectric Point: 5.5500

>AT184264 WP_003519381.1 NZ_CP066273:c212142-211912 [Agrobacterium tumefaciens]
FFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFFF

Download         Length: 231 bp

>AT184264 NZ_CP087584:1512576-1512842 [Providencia rettgeri]
ATGGATATTGAGAACAAGGCGCGAATTCATTGGGCTTGTCGCCGCGGTATGCGTGAGCTAGATATTTCAATCATGCCATT
TTTTGAGTATGAATATGATAGTCTGACAACCAATGATAAACAGGTGTTTGTCCGTTTATTGGAGTGTGCGGACCCTGATT
TATTTAACTGGTTAATGAATCACGGTCGCCCAGATGACGACGAGCTATTTCGTATGGTAAAACTGATTCAGGAAAAAAAT
AAAAATCGTGGTCCTGTGGAAATCTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References