184259

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 5869331..5869878 Replicon chromosome
Accession NZ_CP066267
Organism Pseudomonas tremae strain PA-1-12B

Toxin (Protein)


Gene name relE Uniprot ID A0A3M4CHK7
Locus tag I9H06_RS26655 Protein ID WP_060413327.1
Coordinates 5869603..5869878 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID H1ZWV1
Locus tag I9H06_RS26650 Protein ID WP_015060662.1
Coordinates 5869331..5869603 (+) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I9H06_RS26635 (I9H06_26505) 5864864..5867830 - 2967 WP_122346647.1 Tn3 family transposase -
I9H06_RS26640 (I9H06_26510) 5867834..5868394 - 561 WP_122346646.1 recombinase family protein -
I9H06_RS26645 (I9H06_26515) 5868490..5869113 - 624 WP_122346645.1 hypothetical protein -
I9H06_RS26650 (I9H06_26520) 5869331..5869603 + 273 WP_015060662.1 ribbon-helix-helix domain-containing protein Antitoxin
I9H06_RS26655 (I9H06_26525) 5869603..5869878 + 276 WP_060413327.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I9H06_RS26660 (I9H06_26530) 5870042..5871397 + 1356 WP_248943723.1 tyrosine-type recombinase/integrase -
I9H06_RS26665 (I9H06_26535) 5871423..5872253 - 831 WP_005770909.1 type III effector -
I9H06_RS26670 (I9H06_26540) 5872402..5873193 - 792 Protein_5255 LysR family transcriptional regulator -
I9H06_RS26675 (I9H06_26545) 5873349..5874731 + 1383 WP_122347418.1 NorM family multidrug efflux MATE transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(3-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(10-47)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10753.26 Da        Isoelectric Point: 7.0128

>T184259 WP_060413327.1 NZ_CP066267:5869603-5869878 [Pseudomonas tremae]
MELKWTSKALSDITRLYEFLASVNQPAAARAVQQLTTAPTTLLTNPRIGERLEEFEPRDVRRIQIGQYEMRYEIADSTIY
LLRLWHTREDR

Download         Length: 276 bp

>T184259 NZ_CP087580:c2553559-2552237 [Klebsiella quasipneumoniae]
ATGGCGACGCTCACCACCTGGATGAACAATGCGCGCGTGGGAACCTTAACCCGCCAGGCCAACGGGGCGCACAGTTTCCG
CTATGATGAGGAGTGGCTGCGCAGCCCGCGCGCCAGACCGCTCTCCCTCTCGCTGCCGCTGCAGTATGGCAATATTACCG
CCGACGCGGTGTATCACTATTTTGATAACCTGCTGCCCGACAGCCCGCAGGTCCGCGAGCGGATCGTCAGGCGCTATCAG
GCGCGTTCGAAACAGCCGTTCGATCTGCTGGCCGAGGTCGGGCGGGACAGCGTAGGGGCGGTGACTCTGCTGCCGCCGGG
GGAAGAGGCGCATCTTGCCGCGTTGCGCTGGCAGACGCTGGATGAGGCGCAGCTGACCGCTTTGCTGACCGCCTACCAGT
CGGATATTCCTCTCGGGATGGTGACCGGCCAGGACGATTTTCGTATCTCGGTGGCCGGCGCTCAGGAGAAAACCGCGCTG
CTGCGAATGGGTGAGCACTGGTGTATTCCGCAGGGCACCACCCCGACCACCCATATCATTAAACTGCCCATCGGCGAGAT
AAAGCAGCCCAATGCGACGCTGGATCTGCGTGAAAGCGTGGATAACGAATATCTGTGCCTGGCGCTGGCCAGGGCGTTGG
GCCTGGCGGTGCCGGAGGCGGAGATTATCAACACGCCGCGGATCCGTGCGCTGGCGGTGACCCGCTTCGACCGGCGCTGG
GCGCAGGAGGGGCGCGTGCTGCTGCGTCTGCCGCAGGAGGATCTGTGTCAGGCATTCGGCATACCGTCGTCGATGAAATA
TGAGTCTGACGGCGGGCCGGGTATCGCCGCGATCATGACCTTTCTGCTGGGCTCCAGTGAGGCCCTGAAAGATCGCTATG
ACTTTATGAAGTTCATGGTGTTCCAGTGGCTGACCGGGGCAACGGACGGGCATGCGAAGAACTTCTCGCTCTTTTTGCTG
CCCGGCGGCAGCTACCGGCTCACGCCGTTCTACGACATTATTTCGGCATTTCCGGTGCTGGGCGGGACGGGACTGCATCT
GCGCGACCTGAAGCTGTCGATGGGGCTCAATGCCACAAAAGGGCGGAAAACGGAGATTAACGCTATCTATCCGCGTCATT
TTCTGGCGACCGCCAAAGCGGTTAACTTCCCCCGGGAGCAGATGCTGGCGATCCTGGGCGAGTTTGCCGACCGCGTGCCG
CAGGCCATCGAAAGCGCCCGCCGAACGCTGCCGTCGGACTTTTCCGCCCACGTCTGGCGGGCCATCACGGAGAACATGCT
GAAACTGCACGCCCGCCTGCAGCAAGGGCTGCAGGCGGGATAG

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10076.40 Da        Isoelectric Point: 5.6994

>AT184259 WP_015060662.1 NZ_CP066267:5869331-5869603 [Pseudomonas tremae]
MATTAKTRSVTAHVPVQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSL
STDTPLPVPR

Download         Length: 273 bp

>AT184259 NZ_CP087580:c2553825-2553559 [Klebsiella quasipneumoniae]
ATGAATTCCCCGCAGATATACAGTCCGGTTCAGCTGGCCAATTACCTGAAACTGCTGCGCCAGCAAAATCACTGGACTCA
GGAGGCGCTGGCCAGCCGGATCGGCATTAAACAGGCGACGCTGTCCAATTTTGAAAATCACCCCGACAAAACCACCTTAA
CCACCCTGTTTAAGATCCTCCAGTCGCTGGGGGTGGTGATGACCCTGAACGCCAAACCGGCAGAGACGGCGATGATTCCC
GATAACACCACGGATCTTGACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A3M4CHK7

Antitoxin

Source ID Structure
AlphaFold DB A0A3M4CJB9

References