184258

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PfiT-PfiA/ParE(toxin)
Location 5847697..5848308 Replicon chromosome
Accession NZ_CP066267
Organism Pseudomonas tremae strain PA-1-12B

Toxin (Protein)


Gene name PfiT Uniprot ID A0A0P9J3E0
Locus tag I9H06_RS26520 Protein ID WP_054990073.1
Coordinates 5847958..5848308 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name PfiA Uniprot ID A0A0P9IR64
Locus tag I9H06_RS26515 Protein ID WP_054990072.1
Coordinates 5847697..5847945 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I9H06_RS26485 (I9H06_26360) 5843074..5843835 + 762 WP_081032889.1 alpha/beta fold hydrolase -
I9H06_RS26490 (I9H06_26365) 5843841..5844479 + 639 WP_054990069.1 alanyl-tRNA editing protein -
I9H06_RS26495 (I9H06_26370) 5844498..5845109 + 612 WP_054990070.1 hypothetical protein -
I9H06_RS26500 (I9H06_26375) 5845262..5845765 - 504 Protein_5221 IS5 family transposase -
I9H06_RS26505 (I9H06_26380) 5846027..5846287 + 261 WP_122346902.1 hypothetical protein -
I9H06_RS26510 (I9H06_26385) 5846413..5847375 - 963 WP_054990071.1 tyrosine-type recombinase/integrase -
I9H06_RS26515 (I9H06_26390) 5847697..5847945 + 249 WP_054990072.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
I9H06_RS26520 (I9H06_26395) 5847958..5848308 + 351 WP_054990073.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I9H06_RS26525 (I9H06_26400) 5848934..5849098 - 165 WP_081032891.1 rubredoxin -
I9H06_RS26530 (I9H06_26405) 5849120..5849458 - 339 WP_081032892.1 hypothetical protein -
I9H06_RS26535 (I9H06_26410) 5849476..5850189 - 714 WP_234778524.1 hypothetical protein -
I9H06_RS26540 5850212..5850562 - 351 WP_236534721.1 hypothetical protein -
I9H06_RS26545 5850653..5850934 - 282 WP_236534722.1 hypothetical protein -
I9H06_RS26550 (I9H06_26420) 5850956..5852299 - 1344 WP_236534723.1 saccharopine dehydrogenase C-terminal domain-containing protein -
I9H06_RS26555 (I9H06_26425) 5852661..5853087 + 427 Protein_5232 DUF2778 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-101)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 12949.83 Da        Isoelectric Point: 4.4192

>T184258 WP_054990073.1 NZ_CP066267:5847958-5848308 [Pseudomonas tremae]
MNTFALRFTDVAQQSLEDQVEHLAVHQGFSSAAQRIDSLIDAIQDKLLSTPLGYPVSPQLSELGVLHYRELNTDGYRIFY
EVMDSEGITVIVVLLVLGGKQSVEQALIRYCLLQPI

Download         Length: 351 bp

>T184258 NZ_CP087580:1865440-1865542 [Klebsiella quasipneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9378.78 Da        Isoelectric Point: 9.8450

>AT184258 WP_054990072.1 NZ_CP066267:5847697-5847945 [Pseudomonas tremae]
MRVETISYLKRNAADLPLDEPLVVTQNGVPAYVVESYADRKRRDESIALVKLLAISSREYAQGKHCSTDELKARLSRRFI
QK

Download         Length: 249 bp

>AT184258 NZ_CP087580:c1865546-1865399 [Klebsiella quasipneumoniae]
AGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTG
GCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGTCTGCG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0P9J3E0

Antitoxin

Source ID Structure
AlphaFold DB A0A0P9IR64

References