Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2013737..2013882 Replicon chromosome
Accession NZ_CP066254
Organism Klebsiella pneumoniae strain CRKP78R

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2013773..2013875 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2013737..2013882 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JCR35_RS09855 2008867..2010927 + 2061 WP_004151449.1 oligopeptidase B -
JCR35_RS09860 2010931..2011590 - 660 WP_002911407.1 exodeoxyribonuclease X -
JCR35_RS09865 2011669..2011899 - 231 WP_002911406.1 DNA polymerase III subunit theta -
JCR35_RS09870 2012012..2012386 + 375 WP_004151448.1 CopC domain-containing protein YobA -
JCR35_RS09875 2012390..2013259 + 870 WP_062955019.1 copper homeostasis membrane protein CopD -
JCR35_RS09880 2013276..2013614 + 339 WP_002911404.1 YebY family protein -
- 2013737..2013882 - 146 - - Antitoxin
- 2013773..2013875 + 103 - - Toxin
JCR35_RS09885 2014250..2014393 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
JCR35_RS09890 2014498..2015466 - 969 WP_004151446.1 VirK/YbjX family protein -
JCR35_RS09895 2015623..2016276 + 654 WP_004180432.1 protein-serine/threonine phosphatase -
JCR35_RS09900 2016273..2016464 - 192 WP_002911395.1 YebW family protein -
JCR35_RS09905 2016562..2016801 - 240 WP_002911393.1 YebV family protein -
JCR35_RS09910 2016917..2018350 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T184230 NZ_CP066254:2013773-2013875 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT184230 NZ_CP066254:c2013882-2013737 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References