Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1918618..1920166 Replicon chromosome
Accession NZ_CP066203
Organism Methylacidimicrobium sp. B4

Toxin (Protein)


Gene name rlegT Uniprot ID -
Locus tag MacB4_RS09085 Protein ID WP_206863526.1
Coordinates 1919228..1920166 (+) Length 313 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID -
Locus tag MacB4_RS09080 Protein ID WP_206863525.1
Coordinates 1918618..1919238 (+) Length 207 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
MacB4_RS09055 1914282..1915319 - 1038 WP_206863522.1 Rieske 2Fe-2S domain-containing protein -
MacB4_RS09060 1915410..1916273 - 864 WP_206863523.1 tetratricopeptide repeat protein -
MacB4_RS09065 1916386..1917216 - 831 WP_206863524.1 ATP-binding cassette domain-containing protein -
MacB4_RS09070 1918125..1918367 - 243 Protein_1770 DUF1738 domain-containing protein -
MacB4_RS09075 1918322..1918570 + 249 WP_206865046.1 hypothetical protein -
MacB4_RS09080 1918618..1919238 + 621 WP_206863525.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
MacB4_RS09085 1919228..1920166 + 939 WP_206863526.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
MacB4_RS09090 1920384..1920560 + 177 WP_206865047.1 hypothetical protein -
MacB4_RS09095 1920557..1921609 + 1053 WP_206863527.1 DUF1016 family protein -
MacB4_RS09100 1921606..1921704 + 99 Protein_1776 type I restriction endonuclease subunit S -
MacB4_RS09105 1922416..1922952 + 537 WP_206863528.1 hypothetical protein -
MacB4_RS09110 1922965..1923555 + 591 WP_024808799.1 DUF4433 domain-containing protein -
MacB4_RS09115 1923566..1924693 + 1128 WP_206863529.1 macro domain-containing protein -
MacB4_RS09120 1924849..1925127 + 279 WP_206863530.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(38-257)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(12-55)


Sequences

Toxin        


Download         Length: 313 a.a.        Molecular weight: 34379.33 Da        Isoelectric Point: 4.8849

>T184168 WP_206863526.1 NZ_CP066203:1919228-1920166 [Methylacidimicrobium sp. B4]
MPRKPRNVGASVRARLLDRARVQRSDFQILLTRYALERLLYRLSISGHRDRFVLKGAMLFVTWVADLFRSTRDLDLLGYG
DNEAKAIAETFRAICAQPVTDDGVVFDVAGLEAAPIREEGEYGGVRVRASATIDGARIPIRVDIGFGDAITPAPVEIDYP
ALLDAPAPHLRAYPVETVVAEKFEALVTLGMANSRLKDFYDLWLIAQTFEFHESTLVEAVRCTFERRATKLPVDIPIGLS
DEFAEAWGAQWQTFLGRERMTAVPGAFSAVIADLGAFLIPLAGAAEDGRVWLPGGPWLQPASSTDANEMKSE

Download         Length: 939 bp

>T184168 NZ_CP087392:3677265-3677519 [Pectobacterium parvum]
ATGAACAAACGACACCAGAAAACGCTGTCAGATGTCTTTTCCCGTCCGGTTAGCGGTTCGATAAAGTGGAGTGATATTGA
ATCGTTGTTTATCGCACTAGGGGCAGAAGTACACGAAAGGGAAGGTTCAAGGGTTGCGGTACTGCTGAACGGTGAGAAAA
GGATCTTTCATCGCCCACACCCCAGACCAACCACTGACAAGGGGGCGGTTAACTCCATTCGGATATGGTTAGACAGTTTA
GGGGTACGACCATGA

Antitoxin


Download         Length: 207 a.a.        Molecular weight: 23407.45 Da        Isoelectric Point: 10.8473

>AT184168 WP_206863525.1 NZ_CP066203:1918618-1919238 [Methylacidimicrobium sp. B4]
MTSISAQRTRALDLLKTRGMLRLKDFVAEGIGPETLARLMREKAVVRPARGLYQLLDAQIEAAHMLAEAAVLVPKGVVCL
TSALQFHELTLQMPSAVWMAIERTAWRPRIDYPRIRFVRFTGAALTEGITRHRIESTNVPITDPARTVVDCFRYRAKVGL
DVAMEGLREGLRRRRCTPDELWRYARKARVWSVMRPYVEAMAADAT

Download         Length: 621 bp

>AT184168 NZ_CP087392:3677516-3677857 [Pectobacterium parvum]
ATGATTAATACACTGCAAATCGACGGCCACACTGCCGTCATCGCTTTTGACCCAGAAATTGAGATGTTTAGAGGGGAGTT
TGTCGGGCTTAACGGCGGCGCGGATTTCTATGCTTATAGCGTAGAAGAGTTGAAAAAAGAAGGTGCCACATCGCTTGCCG
TATTTCTTGATGAGTGCCGCCATGATGGCATTGAACCGTACAAATCTTATAGCGGTAAAGTGACCACTCGCCTCACGCCG
GAACGCCACGCAGCGTTAGCAGTAACGGCACAGGCCAACGGGGTGTCAATTAACGAGCTGTTAAACGAAGGCGTCGATCT
CGTCATTGAGCGTCATTCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References