Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pemIK/MazF(toxin) |
| Location | 1757703..1758345 | Replicon | chromosome |
| Accession | NZ_CP066187 | ||
| Organism | Bacillus cytotoxicus strain E28.3 | ||
Toxin (Protein)
| Gene name | pemK | Uniprot ID | J8CWW5 |
| Locus tag | JC772_RS09205 | Protein ID | WP_000635963.1 |
| Coordinates | 1757995..1758345 (+) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | pemI | Uniprot ID | R8PTJ6 |
| Locus tag | JC772_RS09200 | Protein ID | WP_000004571.1 |
| Coordinates | 1757703..1757990 (+) | Length | 96 a.a. |
Genomic Context
Location: 1754733..1755092 (360 bp)
Type: Others
Protein ID: WP_011983363.1
Type: Others
Protein ID: WP_011983363.1
Location: 1755248..1756198 (951 bp)
Type: Others
Protein ID: WP_041810183.1
Type: Others
Protein ID: WP_041810183.1
Location: 1756320..1757489 (1170 bp)
Type: Others
Protein ID: WP_011983365.1
Type: Others
Protein ID: WP_011983365.1
Location: 1757703..1757990 (288 bp)
Type: Antitoxin
Protein ID: WP_000004571.1
Type: Antitoxin
Protein ID: WP_000004571.1
Location: 1757995..1758345 (351 bp)
Type: Toxin
Protein ID: WP_000635963.1
Type: Toxin
Protein ID: WP_000635963.1
Location: 1758410..1760578 (2169 bp)
Type: Others
Protein ID: WP_048721313.1
Type: Others
Protein ID: WP_048721313.1
Location: 1761173..1761637 (465 bp)
Type: Others
Protein ID: WP_011983367.1
Type: Others
Protein ID: WP_011983367.1
Location: 1754082..1754642 (561 bp)
Type: Others
Protein ID: WP_048721301.1
Type: Others
Protein ID: WP_048721301.1
Location: 1760652..1760786 (135 bp)
Type: Others
Protein ID: WP_087094358.1
Type: Others
Protein ID: WP_087094358.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JC772_RS09180 (JC772_09180) | 1754082..1754642 | - | 561 | WP_048721301.1 | rhomboid family intramembrane serine protease | - |
| JC772_RS09185 (JC772_09185) | 1754733..1755092 | + | 360 | WP_011983363.1 | holo-ACP synthase | - |
| JC772_RS09190 (JC772_09190) | 1755248..1756198 | + | 951 | WP_041810183.1 | outer membrane lipoprotein carrier protein LolA | - |
| JC772_RS09195 (JC772_09195) | 1756320..1757489 | + | 1170 | WP_011983365.1 | alanine racemase | - |
| JC772_RS09200 (JC772_09200) | 1757703..1757990 | + | 288 | WP_000004571.1 | antitoxin EndoAI | Antitoxin |
| JC772_RS09205 (JC772_09205) | 1757995..1758345 | + | 351 | WP_000635963.1 | type II toxin-antitoxin system endoribonuclease NdoA | Toxin |
| JC772_RS09210 (JC772_09210) | 1758410..1760578 | + | 2169 | WP_048721313.1 | Tex family protein | - |
| JC772_RS09215 (JC772_09215) | 1760652..1760786 | - | 135 | WP_087094358.1 | cortex morphogenetic protein CmpA | - |
| JC772_RS09220 (JC772_09220) | 1761173..1761637 | + | 465 | WP_011983367.1 | SprT family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12974.12 Da Isoelectric Point: 5.7168
>T184152 WP_000635963.1 NZ_CP066187:1757995-1758345 [Bacillus cytotoxicus]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEVMMIRVDEALQISLGLIDF
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEVMMIRVDEALQISLGLIDF
Download Length: 351 bp
>T184152 NZ_CP087390:2873568-2873855 [Enterobacter sp. AN-K1]
ATGCCTATAGAGTATGAGTGGGATAGCAATAAGGCGAAAAGCAATCTGCAAAAACACGCCATTCGTTTTGAAGATGCAGT
TCTGGTTTTTGACGATCCCTGCCATTTGTCTGTTCAGGATCGTTATGAAAACGGGGAGTTTCGCTGGCAAACCATTGGTC
TTGTACAGGGTGTTATTGTCATTCTGGTCGCGCACACGGTATGTTTTGAAAGCGGGGATGAAATCATACGTATCATCAGT
GCGCGTAAAGCGGATCGTAAAGAGAGGAGGCGTTATGAGCATCGTTAA
ATGCCTATAGAGTATGAGTGGGATAGCAATAAGGCGAAAAGCAATCTGCAAAAACACGCCATTCGTTTTGAAGATGCAGT
TCTGGTTTTTGACGATCCCTGCCATTTGTCTGTTCAGGATCGTTATGAAAACGGGGAGTTTCGCTGGCAAACCATTGGTC
TTGTACAGGGTGTTATTGTCATTCTGGTCGCGCACACGGTATGTTTTGAAAGCGGGGATGAAATCATACGTATCATCAGT
GCGCGTAAAGCGGATCGTAAAGAGAGGAGGCGTTATGAGCATCGTTAA
Antitoxin
Download Length: 96 a.a. Molecular weight: 10748.30 Da Isoelectric Point: 8.9605
>AT184152 WP_000004571.1 NZ_CP066187:1757703-1757990 [Bacillus cytotoxicus]
VSESSVTTEIVVRLPKQVVTELDGIGKQENKNRHELICQATQLLLRQHKTKKRYQHESMRRGYIEMGKINLGIASEAFLA
EYEAAHTVERLVSGG
VSESSVTTEIVVRLPKQVVTELDGIGKQENKNRHELICQATQLLLRQHKTKKRYQHESMRRGYIEMGKINLGIASEAFLA
EYEAAHTVERLVSGG
Download Length: 288 bp
>AT184152 NZ_CP087390:2873842-2874144 [Enterobacter sp. AN-K1]
ATGAGCATCGTTAAACATAAACGCGGTAGTGCACCGGAAGTGAGTGCCCGCCGGGAGGCTGAACTCAAAGCGCTGGCGGA
TAAACCCGACAGGGAAATTGATTACAGCGATATACCGGCCACGGAGGATGATCGCTGGGCCGGTGCCGTGCGGGGAAAAT
TCTATCGACCGCTCAAAACTCAGGCATCAGTACGCATTGACGCCGACGTGATGGAGTGGCTTAAACGGCCAGGGAAAGGT
TACCAGACGCGGCTTAATGCCATTTTGCGCGAGGCGATGCTGCGCGATCAGAACAAAAAATAA
ATGAGCATCGTTAAACATAAACGCGGTAGTGCACCGGAAGTGAGTGCCCGCCGGGAGGCTGAACTCAAAGCGCTGGCGGA
TAAACCCGACAGGGAAATTGATTACAGCGATATACCGGCCACGGAGGATGATCGCTGGGCCGGTGCCGTGCGGGGAAAAT
TCTATCGACCGCTCAAAACTCAGGCATCAGTACGCATTGACGCCGACGTGATGGAGTGGCTTAAACGGCCAGGGAAAGGT
TACCAGACGCGGCTTAATGCCATTTTGCGCGAGGCGATGCTGCGCGATCAGAACAAAAAATAA