Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pemIK/MazF(toxin) |
| Location | 670419..671061 | Replicon | chromosome |
| Accession | NZ_CP066184 | ||
| Organism | Bacillus cytotoxicus strain SM1.1 | ||
Toxin (Protein)
| Gene name | pemK | Uniprot ID | J8CWW5 |
| Locus tag | JC777_RS04110 | Protein ID | WP_000635963.1 |
| Coordinates | 670419..670769 (-) | Length | 117 a.a. |
Antitoxin (Protein)
| Gene name | pemI | Uniprot ID | R8PTJ6 |
| Locus tag | JC777_RS04115 | Protein ID | WP_000004571.1 |
| Coordinates | 670774..671061 (-) | Length | 96 a.a. |
Genomic Context
Location: 667978..668112 (135 bp)
Type: Others
Protein ID: WP_087097560.1
Type: Others
Protein ID: WP_087097560.1
Location: 674122..674682 (561 bp)
Type: Others
Protein ID: WP_048721301.1
Type: Others
Protein ID: WP_048721301.1
Location: 667135..667599 (465 bp)
Type: Others
Protein ID: WP_011983367.1
Type: Others
Protein ID: WP_011983367.1
Location: 668186..670354 (2169 bp)
Type: Others
Protein ID: WP_011983366.1
Type: Others
Protein ID: WP_011983366.1
Location: 670419..670769 (351 bp)
Type: Toxin
Protein ID: WP_000635963.1
Type: Toxin
Protein ID: WP_000635963.1
Location: 670774..671061 (288 bp)
Type: Antitoxin
Protein ID: WP_000004571.1
Type: Antitoxin
Protein ID: WP_000004571.1
Location: 671275..672444 (1170 bp)
Type: Others
Protein ID: WP_011983365.1
Type: Others
Protein ID: WP_011983365.1
Location: 672566..673516 (951 bp)
Type: Others
Protein ID: WP_041810183.1
Type: Others
Protein ID: WP_041810183.1
Location: 673672..674031 (360 bp)
Type: Others
Protein ID: WP_011983363.1
Type: Others
Protein ID: WP_011983363.1
Loading, please wait
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| JC777_RS04095 (JC777_04095) | 667135..667599 | - | 465 | WP_011983367.1 | SprT family protein | - |
| JC777_RS04100 (JC777_04100) | 667978..668112 | + | 135 | WP_087097560.1 | cortex morphogenetic protein CmpA | - |
| JC777_RS04105 (JC777_04105) | 668186..670354 | - | 2169 | WP_011983366.1 | Tex family protein | - |
| JC777_RS04110 (JC777_04110) | 670419..670769 | - | 351 | WP_000635963.1 | type II toxin-antitoxin system endoribonuclease NdoA | Toxin |
| JC777_RS04115 (JC777_04115) | 670774..671061 | - | 288 | WP_000004571.1 | antitoxin EndoAI | Antitoxin |
| JC777_RS04120 (JC777_04120) | 671275..672444 | - | 1170 | WP_011983365.1 | alanine racemase | - |
| JC777_RS04125 (JC777_04125) | 672566..673516 | - | 951 | WP_041810183.1 | outer membrane lipoprotein carrier protein LolA | - |
| JC777_RS04130 (JC777_04130) | 673672..674031 | - | 360 | WP_011983363.1 | holo-ACP synthase | - |
| JC777_RS04135 (JC777_04135) | 674122..674682 | + | 561 | WP_048721301.1 | rhomboid family intramembrane serine protease | - |
Associated MGEs
Loading, please wait
MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 117 a.a. Molecular weight: 12974.12 Da Isoelectric Point: 5.7168
>T184148 WP_000635963.1 NZ_CP066184:c670769-670419 [Bacillus cytotoxicus]
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEVMMIRVDEALQISLGLIDF
MIVKRGDVYFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKKYGFERDSVILLEQI
RTIDKQRLTDKITHLDEVMMIRVDEALQISLGLIDF
Download Length: 351 bp
>T184148 NZ_CP087390:1151507-1151806 [Enterobacter sp. AN-K1]
ATGATTAATCATTTTCGGGATCAATGGCTTGAGGATTTTTTTCTCTACGGGAGATCGAGCAATGTTATCCCTTTGAATCT
GGAAACAGCGCTTGCAAGAAAGCTCGACATCATCAATGCGGCCATGTCGCACCTGGATTTACGATCGCCACCGGGCAATA
TGTATGAAGCATTGAGTCCTCCGTTGAAGGGATATTCCTCTATCCGGGTAAACAGACAATACAGGCTTGTATTTCGCTGG
TCAGAGGGAAAAGCAGACGATCTCTATCTCTCTCCACACAAGTACACGCAACACAAGTGA
ATGATTAATCATTTTCGGGATCAATGGCTTGAGGATTTTTTTCTCTACGGGAGATCGAGCAATGTTATCCCTTTGAATCT
GGAAACAGCGCTTGCAAGAAAGCTCGACATCATCAATGCGGCCATGTCGCACCTGGATTTACGATCGCCACCGGGCAATA
TGTATGAAGCATTGAGTCCTCCGTTGAAGGGATATTCCTCTATCCGGGTAAACAGACAATACAGGCTTGTATTTCGCTGG
TCAGAGGGAAAAGCAGACGATCTCTATCTCTCTCCACACAAGTACACGCAACACAAGTGA
Antitoxin
Download Length: 96 a.a. Molecular weight: 10748.30 Da Isoelectric Point: 8.9605
>AT184148 WP_000004571.1 NZ_CP066184:c671061-670774 [Bacillus cytotoxicus]
VSESSVTTEIVVRLPKQVVTELDGIGKQENKNRHELICQATQLLLRQHKTKKRYQHESMRRGYIEMGKINLGIASEAFLA
EYEAAHTVERLVSGG
VSESSVTTEIVVRLPKQVVTELDGIGKQENKNRHELICQATQLLLRQHKTKKRYQHESMRRGYIEMGKINLGIASEAFLA
EYEAAHTVERLVSGG
Download Length: 288 bp
>AT184148 NZ_CP087390:1151817-1152182 [Enterobacter sp. AN-K1]
ATGACACTTCAACAGGCACTCCGCAAACCCACCACGCCGGGCGAGGTGTTGCAGTATGAATATCTTGAACCGCTCAATCT
GAAAATCAACGATCTGGCAGAGATGCTAAATGTACACCGCAATACCGTAAGCGCGTTGGTCAATAACAATCGCAAACTTA
CTGCCGATATGGCGATCAAACTGGCAAAAGCCTTTAATACCACTATTGAATTTTGGCTGAACTTACAGCTAAACGTTGAT
ATCTGGGAAGCGCAATCTAACTCCCGCACGCAGGAGGAGTTAAGCCGGATAAAAACCGTTGCGGAAGTCATGGCGAAGCG
AAAACTTGGCAAGCCAGACGTTACCCTGCACGGGAACAGCGCATAA
ATGACACTTCAACAGGCACTCCGCAAACCCACCACGCCGGGCGAGGTGTTGCAGTATGAATATCTTGAACCGCTCAATCT
GAAAATCAACGATCTGGCAGAGATGCTAAATGTACACCGCAATACCGTAAGCGCGTTGGTCAATAACAATCGCAAACTTA
CTGCCGATATGGCGATCAAACTGGCAAAAGCCTTTAATACCACTATTGAATTTTGGCTGAACTTACAGCTAAACGTTGAT
ATCTGGGAAGCGCAATCTAACTCCCGCACGCAGGAGGAGTTAAGCCGGATAAAAACCGTTGCGGAAGTCATGGCGAAGCG
AAAACTTGGCAAGCCAGACGTTACCCTGCACGGGAACAGCGCATAA