Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 736170..736672 Replicon chromosome
Accession NZ_CP066167
Organism Spongiibacter sp. CSC3.9

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I6N98_RS03295 Protein ID WP_198570388.1
Coordinates 736170..736424 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag I6N98_RS03300 Protein ID WP_198570389.1
Coordinates 736421..736672 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6N98_RS03270 731912..732718 + 807 WP_198570383.1 septal ring lytic transglycosylase RlpA family protein -
I6N98_RS03275 732747..733910 + 1164 WP_198570384.1 D-alanyl-D-alanine carboxypeptidase -
I6N98_RS03280 733938..734207 + 270 WP_198570385.1 DUF493 domain-containing protein -
I6N98_RS03285 734244..734951 + 708 WP_198570386.1 lipoyl(octanoyl) transferase LipB -
I6N98_RS03290 734948..735931 + 984 WP_198570387.1 lipoyl synthase -
I6N98_RS03295 736170..736424 - 255 WP_198570388.1 Txe/YoeB family addiction module toxin Toxin
I6N98_RS03300 736421..736672 - 252 WP_198570389.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
I6N98_RS03305 736811..737059 + 249 WP_198570390.1 hypothetical protein -
I6N98_RS03310 737419..738573 - 1155 WP_198570391.1 YbfB/YjiJ family MFS transporter -
I6N98_RS03315 738769..739248 + 480 WP_198570392.1 GNAT family N-acetyltransferase -
I6N98_RS03320 739527..740255 + 729 WP_198570393.1 glutamine amidotransferase -
I6N98_RS03325 740252..740443 - 192 WP_198570394.1 CopG family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10286.93 Da        Isoelectric Point: 9.9936

>T184120 WP_198570388.1 NZ_CP066167:c736424-736170 [Spongiibacter sp. CSC3.9]
VKLIFAEKAWEDYLYWQKTDKQTLKRINTLIKEIKREPFEGIGKPEPLKHALSGYWSRRINDEHRMVYKIHQDSLLIAQL
RYHY

Download         Length: 255 bp

>T184120 NZ_CP087377:1304096-1304407 [Escherichia coli]
ATGCACATCATTTCGAAAGCGCCATTTGAAGAGTGTGCGCGCAAATATCCTAACGACGCTCTGGCTCTACACTCATTGTA
TCGGGTTATTAAGGAAACGGATTTTTCTACACCAGAAGAAATGCGAACGGCGTTTCCTAACCTCGACAATTTTAAATATC
GCAACAAATGGTACGTTCTGGATGTCGGCGGGAACAATCTTAGGGTTATTGCCTACATAAACTTTGTTAATAAGCGGTTC
TTTGTGAAGCACATAACGAATCACGCAGAGTATGACAAACTGACACGTTACTACAGAGAGAACAAAGAATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9259.48 Da        Isoelectric Point: 4.4929

>AT184120 WP_198570389.1 NZ_CP066167:c736672-736421 [Spongiibacter sp. CSC3.9]
MDSISYTAARSNLAKTMEQVCNDHAPIAITRKGEGAVVMISMDDYQALEETAYLLRSPKNTRRLIESIAELEDGKGQEKE
LIE

Download         Length: 252 bp

>AT184120 NZ_CP087377:1304404-1304823 [Escherichia coli]
ATGACTGCTAATGCTGCACGCGCTGTTAAAGCAACAAGAGAACTGGTCAATGCAGTCCCCTTTCTGGGAGGCAGTGACTC
AGAAGATGATTATCGTGAAGCACTGGAACTGGTCGAATATTTGATTGAAGAAGATGACACCAATCCACTTATCGACTTTC
TGGCGAGCCGCATTGCAGAATATGAAAACAACAACGAAAAGTTTGCAGAGTTCGACAAAGCCGTTGCAGCAATGCCGGTT
GGCGTGGCCTTACTTCGTACGCTGATTGATCAACATAATTTGACCTATGCGGATTTGAAGAACGAAATCGGCTCTAAATC
TCTGGTCAGTCAGATTTTGTCTGGGCAACGATCCCTGACGATATCCCATATTAAGGCACTTTCAGCCCGATTTGGCGTTA
AGCCGGAATGGTTTCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References