Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2649660..2649805 Replicon chromosome
Accession NZ_CP066143
Organism Klebsiella pneumoniae U-0608239

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2649667..2649769 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2649660..2649805 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6N99_RS13225 2645191..2646624 + 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
I6N99_RS13230 2646740..2646979 + 240 WP_002911393.1 YebV family protein -
I6N99_RS13235 2647077..2647268 + 192 WP_002911395.1 YebW family protein -
I6N99_RS13240 2647265..2647918 - 654 WP_009307541.1 protein-serine/threonine phosphatase -
I6N99_RS13245 2648075..2649043 + 969 WP_004151446.1 VirK/YbjX family protein -
I6N99_RS13250 2649148..2649291 + 144 WP_002911398.1 Ecr family regulatory small membrane protein -
- 2649660..2649805 + 146 - - Antitoxin
- 2649667..2649769 - 103 - - Toxin
I6N99_RS13255 2649928..2650266 - 339 WP_009307539.1 YebY family protein -
I6N99_RS13260 2650283..2651152 - 870 WP_009307538.1 copper homeostasis membrane protein CopD -
I6N99_RS13265 2651156..2651530 - 375 WP_004151448.1 CopC domain-containing protein YobA -
I6N99_RS13270 2651643..2651873 + 231 WP_002911406.1 DNA polymerase III subunit theta -
I6N99_RS13275 2651952..2652611 + 660 WP_002911407.1 exodeoxyribonuclease X -
I6N99_RS13280 2652615..2654675 - 2061 WP_004151449.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T184040 NZ_CP066143:c2649769-2649667 [Klebsiella pneumoniae U-0608239]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT184040 NZ_CP066143:2649660-2649805 [Klebsiella pneumoniae U-0608239]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References