Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2941794..2942637 Replicon chromosome
Accession NZ_CP066132
Organism Morganella morganii strain FAM24676

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JC825_RS14095 Protein ID WP_218454420.1
Coordinates 2941794..2942201 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag JC825_RS14100 Protein ID WP_072056892.1
Coordinates 2942350..2942637 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JC825_RS14075 (JC825_14080) 2937761..2939494 - 1734 WP_218454419.1 single-stranded-DNA-specific exonuclease RecJ -
JC825_RS14080 (JC825_14085) 2939517..2940209 - 693 WP_107678964.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JC825_RS14085 (JC825_14090) 2940222..2941136 - 915 WP_046894461.1 site-specific tyrosine recombinase XerD -
JC825_RS14090 (JC825_14095) 2941270..2941788 + 519 WP_182105148.1 flavodoxin FldB -
JC825_RS14095 (JC825_14100) 2941794..2942201 - 408 WP_218454420.1 protein YgfX Toxin
JC825_RS14100 (JC825_14105) 2942350..2942637 - 288 WP_072056892.1 FAD assembly factor SdhE Antitoxin
JC825_RS14105 (JC825_14110) 2942915..2943898 + 984 WP_218454421.1 tRNA-modifying protein YgfZ -
JC825_RS14110 (JC825_14115) 2943978..2944583 + 606 WP_218454422.1 HD domain-containing protein -
JC825_RS14115 (JC825_14120) 2944644..2947520 - 2877 WP_218454423.1 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-80)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15533.31 Da        Isoelectric Point: 11.2400

>T184019 WP_218454420.1 NZ_CP066132:c2942201-2941794 [Morganella morganii]
VVLWKSVLRVSFKTQVFSTLIYGVLALSVLFAPWPGKTSFIWLPLTLLLIAGWGRTQYKISKRAGPASLQNHNRILWRKS
EWEITKPPYITRLGIRLHLRSLTSGRQKYLWIASDSVPAEAWSSLNQLLLQYPDI

Download         Length: 408 bp

>T184019 NZ_CP087291:101172-101570 [Escherichia coli]
ATGCTGAAGTTTATGCTCGATACCAACATCTGCATTTTCACGATGAAGAACAAACCCGCCAGCGTCAGGGAGCGTTTTAA
CCTGAACCAGGGGAGAATGTGTATCAGTTCGGTCACCCTGATGGAGCTGATATATGGTGCAGAAAAAAGCCAGATGCCTG
AACGTAATCTCGCTGTGATCGAGGGATTTGTTTCCCGCATTGATGTTCTGGATTACGACGCTGCCGCAGCCACACACAGC
GGCCAGATAAGAGCAGAACTTGCCCGTCAGGGACGCCCTGTCGGGCCATTTGATCAAATGATCGCAGGTCATGCCCGCAG
TCGGGGACTGATTATTGTGACTAATAACACCCGGGAATTTGAACGTGTGGACGGTCTGAGAATTGAAGACTGGAGCTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11301.84 Da        Isoelectric Point: 4.7921

>AT184019 WP_072056892.1 NZ_CP066132:c2942637-2942350 [Morganella morganii]
VLDIENKARIHWACRRGMRELDIAIMPFFQHEYDTLTDGQKQDFIQLLTCPDPDLFNWLMNKGRPDDEALYQIIRLIQER
NQARMAAQNSAYYPD

Download         Length: 288 bp

>AT184019 NZ_CP087291:100945-101172 [Escherichia coli]
ATGGAAACCACCGTATTTTTCAGCAACCGCAGCCAGGCGGTCAGACTGCCAAAAGCGGTTGCATTGCCGGAAAACGTAAA
ACGCGTTGAAGTGATTGCTGTCGGACGAACCAGAATCATTACGCCAGCCGGAGAGACATGGGACGAATGGTTCGACGGAC
ACAACGTCAGCGCCGATTTTATGGATAACAGGGAACAGCCCGGCATGCAGGAAAGGGAGTCATTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References