Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2980646..2981489 Replicon chromosome
Accession NZ_CP066129
Organism Morganella morganii strain FAM24679

Toxin (Protein)


Gene name cptA Uniprot ID -
Locus tag JC793_RS14235 Protein ID WP_046894463.1
Coordinates 2980646..2981053 (-) Length 136 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID -
Locus tag JC793_RS14240 Protein ID WP_072056892.1
Coordinates 2981202..2981489 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JC793_RS14215 (JC793_14215) 2976613..2978346 - 1734 WP_218426485.1 single-stranded-DNA-specific exonuclease RecJ -
JC793_RS14220 (JC793_14220) 2978369..2979061 - 693 WP_052926858.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
JC793_RS14225 (JC793_14225) 2979074..2979988 - 915 WP_046894461.1 site-specific tyrosine recombinase XerD -
JC793_RS14230 (JC793_14230) 2980122..2980640 + 519 WP_107678965.1 flavodoxin FldB -
JC793_RS14235 (JC793_14235) 2980646..2981053 - 408 WP_046894463.1 protein YgfX Toxin
JC793_RS14240 (JC793_14240) 2981202..2981489 - 288 WP_072056892.1 FAD assembly factor SdhE Antitoxin
JC793_RS14245 (JC793_14245) 2981767..2982750 + 984 WP_218426486.1 tRNA-modifying protein YgfZ -
JC793_RS14250 (JC793_14250) 2982829..2983434 + 606 WP_218426487.1 HD domain-containing protein -
JC793_RS14255 (JC793_14255) 2983495..2986370 - 2876 Protein_2795 aminomethyl-transferring glycine dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-80)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15561.37 Da        Isoelectric Point: 11.2400

>T184010 WP_046894463.1 NZ_CP066129:c2981053-2980646 [Morganella morganii]
VVLWKSVLRVSFKTQVFSTLIYGVLVLSVLFAPWPGKTSFIWLPLTLLLIAGWGRTQYKISKRAGPASLQNHNRILWRKS
EWEITKPPYITRLGIRLHLRSLTSGRQKYLWIASDSVPAEAWSSLNQLLLQYPDI

Download         Length: 408 bp

>T184010 NZ_CP087290:c4504665-4504558 [Escherichia coli]
ATGACGCTCGCGCAGTTTGCCATGATTTTCTGGCACGACCTGGCGGCACCGATCCTGGCGGGGATTATTACCGCAGTGAT
TGTCAGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 11301.84 Da        Isoelectric Point: 4.7921

>AT184010 WP_072056892.1 NZ_CP066129:c2981489-2981202 [Morganella morganii]
VLDIENKARIHWACRRGMRELDIAIMPFFQHEYDTLTDGQKQDFIQLLTCPDPDLFNWLMNKGRPDDEALYQIIRLIQER
NQARMAAQNSAYYPD

Download         Length: 288 bp

>AT184010 NZ_CP087290:4504718-4504779 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References