Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-YefM
Location 482594..483096 Replicon chromosome
Accession NZ_CP066129
Organism Morganella morganii strain FAM24679

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag JC793_RS02150 Protein ID WP_052926004.1
Coordinates 482594..482848 (-) Length 85 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag JC793_RS02155 Protein ID WP_046894052.1
Coordinates 482845..483096 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JC793_RS02125 (JC793_02125) 477681..477824 - 144 WP_218427348.1 hypothetical protein -
JC793_RS02130 (JC793_02130) 477833..478492 - 660 WP_046894048.1 YtjB family periplasmic protein -
JC793_RS02135 (JC793_02135) 478594..479571 + 978 WP_166706942.1 phosphoserine phosphatase -
JC793_RS02140 (JC793_02140) 479597..480985 + 1389 WP_046894049.1 DNA repair protein RadA -
JC793_RS02145 (JC793_02145) 481001..482263 + 1263 WP_046894050.1 multifunctional transcriptional regulator/nicotinamide-nucleotide adenylyltransferase/ribosylnicotinamide kinase NadR -
JC793_RS02150 (JC793_02150) 482594..482848 - 255 WP_052926004.1 Txe/YoeB family addiction module toxin Toxin
JC793_RS02155 (JC793_02155) 482845..483096 - 252 WP_046894052.1 YoeB-YefM toxin-antitoxin system antitoxin YefM Antitoxin
JC793_RS02160 (JC793_02160) 483234..484901 - 1668 WP_046894053.1 energy-dependent translational throttle protein EttA -
JC793_RS02165 (JC793_02165) 485515..487440 + 1926 WP_218427350.1 murein transglycosylase -
JC793_RS02170 (JC793_02170) 487551..487856 + 306 WP_004237105.1 trp operon repressor -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 85 a.a.        Molecular weight: 10019.36 Da        Isoelectric Point: 10.0255

>T184008 WP_052926004.1 NZ_CP066129:c482848-482594 [Morganella morganii]
MTLTFSSQAWEDYLYWQNTDKKTLRRINELIKAAQRTPFSGIGKPEPLKNNLSGWWSRRITEEHRLVYRVTNQGVEVAAC
RYHY

Download         Length: 255 bp

>T184008 NZ_CP087290:c4138054-4137668 [Escherichia coli]
ATGGGTGTGTATAAGGCAAGACGATTCAGCCAAAGCACGAAAAAACTTGGTATTCACGATAAAGTTCTCATGGCTGCCGC
TGAAGAAGTGATGCAGGGCATATGGGAGGCTGATTTAGGTAGCGGTGTCATCAAAAAACGTTTACCCCTCCAACAAGGAA
AGAGTGGTGGAGCCAGAACAATTATCTTTTTTAAATCAGCAAATCATGTGTTTTTTTATGATGGTTGGTCCAAGAGTGGT
CTAAGCAGTAAAGGAACCAAAGAAATCGAAGATGATGAACTGGCGGCCTACAAAAAAATGGCAAATGCATTTCTGGCCTT
TAGCAATAAGCAAATAGAGGATTTGATCGAAACTGGCTTTTTGATTGAGGTGAAAAATGAGCGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9433.77 Da        Isoelectric Point: 4.7863

>AT184008 WP_046894052.1 NZ_CP066129:c483096-482845 [Morganella morganii]
MKTLTYSEVRQNLTAAMNETVDDRIPILITRQKGTACVLLSLDEYQSLEETAYLMRSPNNARRLMDSIDELNAGKGLKKE
INE

Download         Length: 252 bp

>AT184008 NZ_CP087290:c4137678-4137349 [Escherichia coli]
ATGAGCGATAAATTACAAATGATGCTGGAAGATGCAAAGGAACTGAATGCACTGGGCCTGATGTCTGATAGTGAAGTTGA
TGCCATTGCCGTCATGGTCAAAGCTCGTGAAGTCAGCGCCCGTATAGCCAAAGTCAAATCAATGACGGGTGAAGAGATCA
AAGCCATCCGCACCCGATACGGCATGTCACAATCCGTGCTGGCACATACAATGGGAATGTCAAAAGAAAGTGTCTCGAAA
TGGGAACGTAATGAAATAAAACCGAGCGGCCCGGCATTACGTATTTTGAATACATTGGCAATAAAAGGGCCGGAAGTTTT
TGCAAAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References