Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 3281101..3282814 Replicon chromosome
Accession NZ_CP066126
Organism Chromobacterium rhizoryzae strain 32279

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag JC616_RS14670 Protein ID WP_227103885.1
Coordinates 3281101..3282003 (+) Length 301 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag JC616_RS14675 Protein ID WP_227103887.1
Coordinates 3281996..3282814 (+) Length 273 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
JC616_RS14645 3276695..3277840 + 1146 WP_227103881.1 elongation factor P maturation arginine rhamnosyltransferase EarP -
JC616_RS14650 3277903..3278466 + 564 WP_048412240.1 elongation factor P -
JC616_RS14655 3278556..3278990 - 435 Protein_2853 cupin domain-containing protein -
JC616_RS14660 3279402..3280286 + 885 WP_227103883.1 hypothetical protein -
JC616_RS14665 3280333..3281088 + 756 WP_107799130.1 SDR family oxidoreductase -
JC616_RS14670 3281101..3282003 + 903 WP_227103885.1 alpha/beta fold hydrolase Toxin
JC616_RS14675 3281996..3282814 + 819 WP_227103887.1 IclR family transcriptional regulator Antitoxin
JC616_RS14680 3282827..3283627 + 801 WP_227103889.1 SDR family oxidoreductase -
JC616_RS14685 3283617..3285281 + 1665 WP_227103891.1 thiamine pyrophosphate-binding protein -
JC616_RS14690 3285286..3286116 + 831 WP_227103893.1 aspartate dehydrogenase -
JC616_RS14695 3286125..3287603 + 1479 WP_227103896.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(50-281)

Antitoxin

Transcription regulator IclR, C-terminal

(135-257)


Sequences

Toxin        


Download         Length: 301 a.a.        Molecular weight: 31772.22 Da        Isoelectric Point: 8.1951

>T184003 WP_227103885.1 NZ_CP066126:3281101-3282003 [Chromobacterium rhizoryzae]
MSALDLPANADETLLLKLRRRLRQCFPERRLQVNDRVVAYRECGTGDATVVLLHGIGSTSASWMEVAAALAPRARVLAWD
APGYGDTSPLPQARPKADDYAQALEGFLKAAGVTRCALVGHSLGGLMAAAHARRHPQRLERLLLVSPAQGYGAADRRADG
ARVRGERLRALHAQGLAQVADQAPARLLSASADAAARAWVRWNMAQLKEGGYGQAVELLTGDDIARYAPSPLPVTVFCGE
RDLATPPADCQTVAAAFNAPFHLIPGCGHACHVEAPAALADLLSAALAPSHPHTKEAHHG

Download         Length: 903 bp

>T184003 NZ_CP087290:2828474-2828647 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTTCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 273 a.a.        Molecular weight: 29605.09 Da        Isoelectric Point: 7.5498

>AT184003 WP_227103887.1 NZ_CP066126:3281996-3282814 [Chromobacterium rhizoryzae]
MDEQNPNDAAARYTVPALERGLRLLGEFSRGEPTLSAPELARRLALPRSTVFRMLATLEQLGFIERAEGGRDYRLGIAVL
RLGFEYLSSLELTELGLPVLGRLRDRIGHACSLVVRDGRSIVYVAKVNPPSWIASNINIGARLPAHATVFGRILLSELPL
EKLRELYPEEHLDIHSSQTPRNTLELFHLLQQDRERTCLVGEGFFETNISTVAAPVRNHGGAIIAAIGATLPMPRLEPGQ
ADALAGHIRAAAAELSRALGHAGGGMGKVIHL

Download         Length: 819 bp

>AT184003 NZ_CP087290:2828150-2828446 [Escherichia coli]
ATGGAAGGTAAAAACAAGTTCAATACTTATGTTGTTTCTTTTGATTATCCATCATCTTATTCCTCAGTGTTCTTAAGGTT
AAGATCATTGATGTATGATATGAGTTTCTCCTCTATCGTGGCTGATGAATATGGGATACCACGACAACTGAATGAAAACT
CCTTCGCAATAACGACATCGTTAGCCGCAAGTGAAATCGAAGATTTAATCAGGCTTAAATGCTTAGACTTACCGGATATT
GACTTTGACCTCAACATTATGACAGTTGATGACTATTTCCGTCAGTTTTACAAGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References