Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 1001922..1002460 Replicon chromosome
Accession NZ_CP066123
Organism Pseudomonas sp. MPFS

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I9018_RS04435 Protein ID WP_241108829.1
Coordinates 1002182..1002460 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I9018_RS04430 Protein ID WP_083236103.1
Coordinates 1001922..1002185 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I9018_RS04415 (I9018_04425) 997916..1000189 - 2274 WP_241108826.1 TonB-dependent siderophore receptor -
I9018_RS04420 (I9018_04430) 1000398..1001078 + 681 WP_241108827.1 Fe2+-dependent dioxygenase -
I9018_RS04425 (I9018_04435) 1001082..1001867 + 786 WP_241108828.1 tetratricopeptide repeat protein -
I9018_RS04430 (I9018_04440) 1001922..1002185 + 264 WP_083236103.1 ribbon-helix-helix domain-containing protein Antitoxin
I9018_RS04435 (I9018_04445) 1002182..1002460 + 279 WP_241108829.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I9018_RS04440 (I9018_04450) 1002538..1003701 - 1164 WP_068575730.1 type III PLP-dependent enzyme -
I9018_RS04445 (I9018_04455) 1004519..1005676 - 1158 WP_241108830.1 ABC transporter ATP-binding protein -
I9018_RS04450 (I9018_04460) 1005673..1006341 - 669 WP_068575734.1 ABC transporter permease -
I9018_RS04455 (I9018_04465) 1006354..1007247 - 894 WP_241108831.1 glycine betaine ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-44)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10801.57 Da        Isoelectric Point: 10.8284

>T183988 WP_241108829.1 NZ_CP066123:1002182-1002460 [Pseudomonas sp. MPFS]
MRQLKWTSKALSDLARLFEFLAQVNRSAAARTVQSLVRAPDALLSNPRLGEQLEEFKPKDVRRLLVGHYEVRYEIQGMVL
SILRIWHIREDR

Download         Length: 279 bp

>T183988 NZ_CP087290:40568-41884 [Escherichia coli]
ATGCCTAAACTTGTCACTTGGATGAACAACCAGCGGGTAGGCGAGTTAACGAAGTTAGCCAATGGCGCGCACACCTTTAA
GTATGCACCGGAGTGGTTAGCCAGCCGTTATGCCAGACCGTTGTCACTTTCGCTGCCATTGCAGAGGGGGAATATCACCT
CTGATGCCGTATTTAACTTCTTCGATAACCTGTTACCCGATAGCCCGATTGTACGTGATCGGATCGTTAAACGTTATCAT
GCTAAATCCAGACAACCGTTTGATTTATTGTCAGAAATAGGGCGAGACAGCGTTGGTGCCGTAACGTTATTACCCGAAAA
TGAAACCATAACGCGCCCGATAATGGCATGGGAACAGCTCACTGAAGCCAGGCTTGAAGAAGTATTAACGGCTTATAAAG
CAGATATCCCTCTGGGCATGATTAGAGAAGAAAATGACTTTCGCATCTCGGTTGCTGGCGCGCAGGAGAAGACAGCGCTG
CTCAGAATAGGCAATGACTGGTGCATTCCGAAAGGAATAACGCCGACGACGCACATCATTAAATTACCGATTGGCGAAAT
CAGGCAGCCCAATGCGACGCTCGATCTCAGCCAAAGCGTTGATAATGAGTATTACTGTCTGCTGCTGGCGAAAGAACTTG
GGTTGAATGTGCCGGACGCAGAAATCATTAAAGCGGGAAATGTGCGCGCGTTAGCGGTCGAACGTTTTGACAGGCGTTGG
AATGCTGAGCGAACGGTTTTACTTCGCTTGCCACAGGAGGATATGTGTCAGACATTCGGTTTACCTTCATCGGTGAAATA
TGAATCAGATGGAGGCCCAGGCATCGCGCGGATCATGGCTTTTTTGATGGGGTCCAGCGAGGCGCTGAAAGATCGCTATG
ATTTTATGAAGTTTCAGGTGTTCCAGTGGTTGATTGGCGCAACGGATGGCCATGCAAAAAACTTCTCCGTATTTATTCAG
GCTGGCGGCAGTTATCGACTCACGCCATTTTACGACATCATTTCAGCATTTCCGGTATTGGGTGGTGCAGGAATACACAT
CAGCGATCTCAAACTGGCAATGGGGCTTAACGCATCCAAAGGCAAAAAAACGGCAATCGATAAAATTTATCCGCGACATT
TTCTGGCGACAGCAAAGGTGCTGAAATTTCCGCAAGTGCAGATGCATGAAATCCTGAGTGACTTTGCCAGAATGATTCCG
GCAGCACTGGATAACGTGAAGACTTCATTACCGACAGATTTTCCGGAGAACGTGGTGACGGCAGTTGAAACCAATGTGTT
GAGGTTGCACCGTCGGTTAAGCCGAGAATGGTATTAA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9691.09 Da        Isoelectric Point: 5.0878

>AT183988 WP_083236103.1 NZ_CP066123:1001922-1002185 [Pseudomonas sp. MPFS]
MPATKVLTAHIPLDLADKVDQLASRLERSRAWIVKQALVAWVDQEEERRRLTLEALADVDAGRVVDHQSVLAWAESLSGD
NPLPLPK

Download         Length: 264 bp

>AT183988 NZ_CP087290:40302-40568 [Escherichia coli]
ATGATGAGCTTTCAGAAGATCTATAGCCCAACGCAATTGGCGAATGCAATGAAACTGGTTCGCCAGCAAAATGGCTGGAC
GCAGAGCGAGCTGGCGAAAAAAATTGGTATTAAGCAGGCGACGATTTCCAATTTCGAAAACAACCCTGACAATACCACGC
TGACGACCTTTTTTAAGATTTTACAGTCGCTTGAACTCTCAATGACGCTATGCGACACGAAAAATGCCTCGCCAGAATCA
ACAGAACAGCAAGATCTGGAGTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References