Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 739516..740112 Replicon chromosome
Accession NZ_CP066123
Organism Pseudomonas sp. MPFS

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I9018_RS03230 Protein ID WP_241108716.1
Coordinates 739810..740112 (-) Length 101 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I9018_RS03225 Protein ID WP_124345642.1
Coordinates 739516..739806 (-) Length 97 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I9018_RS03205 (I9018_03215) 735778..737916 - 2139 WP_241108714.1 TonB-dependent copper receptor -
I9018_RS03210 (I9018_03220) 738005..738451 - 447 WP_228022251.1 DUF2946 domain-containing protein -
I9018_RS03215 (I9018_03225) 738474..738953 - 480 WP_176719722.1 copper chaperone PCu(A)C -
I9018_RS03220 (I9018_03230) 739018..739416 - 399 WP_241108715.1 DUF2946 domain-containing protein -
I9018_RS03225 (I9018_03235) 739516..739806 - 291 WP_124345642.1 putative addiction module antidote protein Antitoxin
I9018_RS03230 (I9018_03240) 739810..740112 - 303 WP_241108716.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I9018_RS03235 (I9018_03245) 740290..741018 - 729 WP_241108717.1 cobalt-precorrin-6A reductase -
I9018_RS03240 (I9018_03250) 741015..742112 - 1098 WP_241108718.1 cobalt-precorrin-5B (C(1))-methyltransferase -
I9018_RS03245 (I9018_03255) 742105..743349 - 1245 WP_241108719.1 precorrin-6y C5,15-methyltransferase (decarboxylating) subunit CbiE -
I9018_RS03250 (I9018_03260) 743398..744801 + 1404 WP_241108720.1 precorrin-3B synthase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(4-95)

Antitoxin

Uncharacterized protein HI1420

(3-94)


Sequences

Toxin        


Download         Length: 101 a.a.        Molecular weight: 11613.24 Da        Isoelectric Point: 10.8593

>T183987 WP_241108716.1 NZ_CP066123:c740112-739810 [Pseudomonas sp. MPFS]
MFVFEQNQEFSHWLTRLKDPQGKTRVLARIRAAQLGRFGDCVSIGGGVHEMRIHRGPGYRVYFSRRGERIYLLLIGGDKS
TQSRDIQRARQLAHDLKNED

Download         Length: 303 bp

>T183987 NZ_CP087288:173595-174011 [Escherichia coli]
GTGAACAAGATCTATATGCTCGACACGAACATCTGCTCGTTCATCATGCGCGAGCAACCTGAAGCATTGCTTAAGCACCT
GGAGCAGTCGGTGCTGCGCGGTCACCGTATCGTGGTCTCGGCCATCACCTACTCCGAGATGCGCTTCGGTGCCACCGGTC
CGAAGGCCTCGCCACGCCACGTGCAACTGGTTGACGCGTTCTGTGAGAGGCTCGATGCCGTCCTGCCGTGGGACCGCGCC
GCGGTGGATGCGACCACGGAGATTAAGGTGGCACTGCGTCTCGCCGGCACGCCGATCGGTCCGAACGACACGGCGATAGC
CGGACACGCCATCGCTGCCTGTGCCATTCTGGTGACGAATAATGTGAGAGAGTTTGAGCGGGTACCGGGTCTTGTGCTGG
AAGACTGGGTAAGATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10389.97 Da        Isoelectric Point: 6.2732

>AT183987 WP_124345642.1 NZ_CP066123:c739806-739516 [Pseudomonas sp. MPFS]
MRTPVTRFDAADYLKTPQDMVAYLDACFEEDAGDGVLIRAALNDIARARGMTQIARDTGLGRESLYKALGSQGNPEFATI
IKVMKALGLKLQVSPA

Download         Length: 291 bp

>AT183987 NZ_CP087288:173368-173598 [Escherichia coli]
ATGAGAACCGTATCCATTTTTAAAAATGGCAACAACCGTGCTATCCGCCTTCCACGCGATCTGGATTTTGAGGGGGTGAG
CGAGCTGGAGATCGTCCGGGAAGGGGACAGCATCATTCTGCGCCCCGTCCGGCCGACCTGGGGCTCATTCCTGGAGCTAG
AAAAGGCCGATCCGGACTTTATGACGGAGCGCGAGGACGTTGTCAGCGACGAAGGACGAGTTAACCTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References