Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 800168..800691 Replicon chromosome
Accession NZ_CP066119
Organism Acinetobacter bereziniae strain GD03185

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag I9192_RS03740 Protein ID WP_200150101.1
Coordinates 800425..800691 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I9192_RS03735 Protein ID WP_200150100.1
Coordinates 800168..800425 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I9192_RS03715 795544..796560 - 1017 WP_005030968.1 hypothetical protein -
I9192_RS03720 796679..797734 - 1056 WP_034715030.1 tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA -
I9192_RS03730 798195..799565 + 1371 WP_200150099.1 integrase arm-type DNA-binding domain-containing protein -
I9192_RS03735 800168..800425 + 258 WP_200150100.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
I9192_RS03740 800425..800691 + 267 WP_200150101.1 Txe/YoeB family addiction module toxin Toxin
I9192_RS03745 800706..801425 + 720 WP_200150102.1 hypothetical protein -
I9192_RS03750 801550..801786 + 237 WP_200150103.1 transcriptional regulator -
I9192_RS03755 801802..802116 + 315 WP_200150104.1 AlpA family phage regulatory protein -
I9192_RS03760 802119..802763 + 645 WP_200150105.1 hypothetical protein -
I9192_RS03765 802763..803071 + 309 WP_200150106.1 hypothetical protein -
I9192_RS03770 803074..803343 + 270 WP_200150107.1 hypothetical protein -
I9192_RS03775 803344..803691 + 348 WP_200150108.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10379.92 Da        Isoelectric Point: 7.1301

>T183975 WP_200150101.1 NZ_CP066119:800425-800691 [Acinetobacter bereziniae]
MSLSIVFVPDAWDDYVYWQGQDKKTLKRINVLIQAMCRTPFEGIGKPEPLKENLTGYWSRRIADDHRLVYRVTDTEIVII
ACRYHYGD

Download         Length: 267 bp

>T183975 NZ_CP087287:c3734243-3733908 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATACGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTCTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTGCTGATTGGGTAG

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9463.64 Da        Isoelectric Point: 5.0859

>AT183975 WP_200150100.1 NZ_CP066119:800168-800425 [Acinetobacter bereziniae]
MKITTATEARANFKTVLDQTIDDADITIIHRRDGENAVLMSESQYNSIMETLHLLSTPANARALERAIAQDKANHGVKRE
LLDAE

Download         Length: 258 bp

>AT183975 NZ_CP087287:c3734491-3734243 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGGGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References