Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2663348..2663549 Replicon chromosome
Accession NZ_CP066108
Organism Enterobacter hormaechei strain Eho-7

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2663353..2663456 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2663348..2663549 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GVI68_RS12750 (GVI68_12725) 2659609..2661057 + 1449 WP_197347173.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GVI68_RS12755 (GVI68_12730) 2661163..2661402 + 240 WP_006811010.1 YebV family protein -
GVI68_RS12760 (GVI68_12735) 2661437..2662081 - 645 WP_032673898.1 protein-serine/threonine phosphatase -
GVI68_RS12765 (GVI68_12740) 2662249..2663229 + 981 WP_039274015.1 VirK/YbjX family protein -
GVI68_RS12770 (GVI68_12745) 2663275..2663472 + 198 WP_000460990.1 hypothetical protein -
- 2663348..2663549 + 202 - - Antitoxin
- 2663353..2663456 - 104 - - Toxin
GVI68_RS12775 (GVI68_12750) 2663598..2663936 - 339 WP_006811013.1 YebY family protein -
GVI68_RS12780 (GVI68_12755) 2663954..2664823 - 870 WP_006811014.1 copper homeostasis membrane protein CopD -
GVI68_RS12785 (GVI68_12760) 2664825..2665196 - 372 WP_032673899.1 CopC domain-containing protein YobA -
GVI68_RS12790 (GVI68_12765) 2665334..2665564 + 231 WP_003859784.1 DNA polymerase III subunit theta -
GVI68_RS12795 (GVI68_12770) 2665676..2666326 + 651 WP_039274017.1 nitrilase-related carbon-nitrogen hydrolase -
GVI68_RS12800 (GVI68_12775) 2666351..2667013 + 663 WP_006811017.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T183963 NZ_CP066108:c2663456-2663353 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 202 bp

>AT183963 NZ_CP066108:2663348-2663549 [Enterobacter hormaechei]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTGGC
CTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References