Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2664422..2664623 Replicon chromosome
Accession NZ_CP066101
Organism Enterobacter hormaechei strain Eho-8

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2664427..2664530 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2664422..2664623 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
GVI69_RS12755 (GVI69_12730) 2660683..2662131 + 1449 WP_197347173.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -
GVI69_RS12760 (GVI69_12735) 2662237..2662476 + 240 WP_006811010.1 YebV family protein -
GVI69_RS12765 (GVI69_12740) 2662511..2663155 - 645 WP_032673898.1 protein-serine/threonine phosphatase -
GVI69_RS12770 (GVI69_12745) 2663323..2664303 + 981 WP_039274015.1 VirK/YbjX family protein -
GVI69_RS12775 (GVI69_12750) 2664349..2664546 + 198 WP_000460990.1 hypothetical protein -
- 2664422..2664623 + 202 - - Antitoxin
- 2664427..2664530 - 104 - - Toxin
GVI69_RS12780 (GVI69_12755) 2664672..2665010 - 339 WP_006811013.1 YebY family protein -
GVI69_RS12785 (GVI69_12760) 2665028..2665897 - 870 WP_006811014.1 copper homeostasis membrane protein CopD -
GVI69_RS12790 (GVI69_12765) 2665899..2666270 - 372 WP_032673899.1 CopC domain-containing protein YobA -
GVI69_RS12795 (GVI69_12770) 2666408..2666638 + 231 WP_003859784.1 DNA polymerase III subunit theta -
GVI69_RS12800 (GVI69_12775) 2666750..2667400 + 651 WP_039274017.1 nitrilase-related carbon-nitrogen hydrolase -
GVI69_RS12805 (GVI69_12780) 2667425..2668087 + 663 WP_006811017.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T183944 NZ_CP066101:c2664530-2664427 [Enterobacter hormaechei]
GGCAAGGCGATTGAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 202 bp

>AT183944 NZ_CP066101:2664422-2664623 [Enterobacter hormaechei]
CAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTT
GGCATTAATGCAGGCTCAATCGCCTTGCCCTTTAAGAATAGATGACGACGTCAGGTTTTCCAGTCCACAGTAAAAGTGGC
CTGAAAAAAAGCGTCAGAACATCACTAAATGTGAAAAACCGC

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References