Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB(antitoxin)
Location 515115..515733 Replicon chromosome
Accession NZ_CP066073
Organism Streptococcus dysgalactiae strain FDAARGOS_1016

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I6H73_RS02660 Protein ID WP_003058081.1
Coordinates 515115..515456 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I6H73_RS02665 Protein ID WP_003058067.1
Coordinates 515446..515733 (-) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6H73_RS02640 510578..511822 - 1245 WP_115261920.1 site-specific integrase -
I6H73_RS02645 511833..512030 - 198 WP_003058094.1 transposase -
I6H73_RS02650 512050..513153 - 1104 WP_003058088.1 CHAP domain-containing protein -
I6H73_RS02655 513156..515057 - 1902 WP_003058051.1 hypothetical protein -
I6H73_RS02660 515115..515456 - 342 WP_003058081.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6H73_RS02665 515446..515733 - 288 WP_003058067.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
I6H73_RS02670 515804..518302 - 2499 WP_003058044.1 ATP-binding protein -
I6H73_RS02675 518286..518702 - 417 WP_003058056.1 conjugal transfer protein -
I6H73_RS02680 518711..518929 - 219 WP_003058071.1 hypothetical protein -
I6H73_RS02685 518926..519867 - 942 WP_003058075.1 conjugal transfer protein -
I6H73_RS02690 519880..520143 - 264 WP_003058063.1 hypothetical protein -
I6H73_RS02695 520153..520425 - 273 WP_003058046.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - psaA / tufA 366880..598856 231976


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-100)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-90)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13438.41 Da        Isoelectric Point: 7.0067

>T183866 WP_003058081.1 NZ_CP066073:c515456-515115 [Streptococcus dysgalactiae]
MAYNVQITKSAERDLDSIYQFYLDEFSEQSALKVIKSLQDAISFLYVSPLGYTDFDSKINRKIYPQGNLRMIPSKQYLIF
YLIREERVDVLRIIHSRTDYLNNLENLFKNLNL

Download         Length: 342 bp

>T183866 NZ_CP087197:974736-975035 [Pseudomonas sp. B21-012]
ATGAGCTTGTCACTCACCACCTTTGATATGGCAGCCTTGCTCGATAGTGATGAAGCTATCAGCGAGTACCTTTCCCAAGT
TCTGGCGGATGGAGATCATGACGAACTGATACGTGCCCTTGGCCATATCGCCAAGGCGCGCGGCATGAGTCAGATTGCAA
GCGCAAGTGGGTTGGGGCGCGAGAGTCTGTACAAGGCATTAACCCCGGGTGCGAAGCCTCGTTTTGATACTGTACTGAAG
GTCATTCGAGCGTTAGGGATTGATCTTCTGGCTCATCCTCACACTTCCTCGAGGCTCTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10869.33 Da        Isoelectric Point: 4.3885

>AT183866 WP_003058067.1 NZ_CP066073:c515733-515446 [Streptococcus dysgalactiae]
MNTLARDRQYNFRVNADMLNQAKEILEEKHMSLPDALNLFVEQVVVTKDLPIKTPEQVQAESFLNELISELDEGYQDVLK
GNTKPANEVFAKYGL

Download         Length: 288 bp

>AT183866 NZ_CP087197:974441-974734 [Pseudomonas sp. B21-012]
TTGAAATATAGTGTTTTGCAGACACCCAGATTTACCTCGTGGTTAGTTTCTGTGCGCGACCTCCGTGCAAGGTTGGCCAT
CGCACGGCGAATAGAGCGTGCAACGGCAGGAAACCTGGGGGATGTGAAGTCCGTCGGTGGCCAGGTTTCCGAGATGCGCA
TCGATGTGGGTGCGGGTTATCGGGTGTACTTCACGGTTCGGGACGGGATGGTCATTGTTTTGTTGGCAGGGGGTGACAAG
TCATCTCAATCTGCTGATATCCAACTAGCCAGGAAGTTGGCCAAGGAAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References