Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelB(antitoxin)
Location 1913041..1913659 Replicon chromosome
Accession NZ_CP066069
Organism Streptococcus dysgalactiae strain FDAARGOS_1017

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I6H74_RS09450 Protein ID WP_003058081.1
Coordinates 1913318..1913659 (+) Length 114 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I6H74_RS09445 Protein ID WP_003058067.1
Coordinates 1913041..1913328 (+) Length 96 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6H74_RS09415 1908349..1908621 + 273 WP_003058046.1 hypothetical protein -
I6H74_RS09420 1908631..1908894 + 264 WP_003058063.1 hypothetical protein -
I6H74_RS09425 1908907..1909848 + 942 WP_003058075.1 conjugal transfer protein -
I6H74_RS09430 1909845..1910063 + 219 WP_003058071.1 hypothetical protein -
I6H74_RS09435 1910072..1910488 + 417 WP_003058056.1 conjugal transfer protein -
I6H74_RS09440 1910472..1912970 + 2499 WP_003058044.1 ATP-binding protein -
I6H74_RS09445 1913041..1913328 + 288 WP_003058067.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
I6H74_RS09450 1913318..1913659 + 342 WP_003058081.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6H74_RS09455 1913717..1915618 + 1902 WP_003058051.1 hypothetical protein -
I6H74_RS09460 1915621..1916724 + 1104 WP_046177356.1 CHAP domain-containing protein -
I6H74_RS09465 1916744..1916941 + 198 WP_003058094.1 transposase -
I6H74_RS09470 1916952..1918196 + 1245 WP_014612120.1 site-specific integrase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-100)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(11-90)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 13438.41 Da        Isoelectric Point: 7.0067

>T183860 WP_003058081.1 NZ_CP066069:1913318-1913659 [Streptococcus dysgalactiae]
MAYNVQITKSAERDLDSIYQFYLDEFSEQSALKVIKSLQDAISFLYVSPLGYTDFDSKINRKIYPQGNLRMIPSKQYLIF
YLIREERVDVLRIIHSRTDYLNNLENLFKNLNL

Download         Length: 342 bp

>T183860 NZ_CP087195:397996-398286 [Pseudomonas brassicacearum]
ATGACCTATAGCCTCGAATTCGATGCACGGGCACTAAAGGAATGGCGAAAGCTAGGGAATACCGTCCGTGAGCAGTTCAA
AAAGAAGCTCACTACGATCCTGGCCAATCCGCGCATCGAAGCAAACCGACTGCATGCCTTTCCTGATTGCTACAAGATTA
AGCTGCGGAGCAGCGGTTATCGGTTGGTTTATCAGGTGATTGATCAGGAGGTCGTGGTGTTTGTCGTGGCCGTCGACAAA
CGTGAACGAGATCAGGTTTATCGGAAAGCGGCTGAGCGATTAGGTGGTTGA

Antitoxin


Download         Length: 96 a.a.        Molecular weight: 10869.33 Da        Isoelectric Point: 4.3885

>AT183860 WP_003058067.1 NZ_CP066069:1913041-1913328 [Streptococcus dysgalactiae]
MNTLARDRQYNFRVNADMLNQAKEILEEKHMSLPDALNLFVEQVVVTKDLPIKTPEQVQAESFLNELISELDEGYQDVLK
GNTKPANEVFAKYGL

Download         Length: 288 bp

>AT183860 NZ_CP087195:397767-398006 [Pseudomonas brassicacearum]
ATGGCTTCCATCAACGTCCGTATCGACGACGACCTCAAGGCGCGTGCATACCGCGAGCTGGAAAAGCTCGGCGTTACCCC
TTCTGAGCTGATGCGCCAAGCCTTGCAGTACGTAGCGGAGCGCGGCCAGTTGCCGTTCAAGCCCGTCCTGATGACCGAGG
ACGATGAAGCCTTGATCGCAACGGTGCGCGAGCGACTCGCCGCCCCGCAGCGGGTTAAGGTTTCGCTAGATGACCTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References