Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) TsdAT/-
Location 507058..507570 Replicon chromosome
Accession NZ_CP066062
Organism Staphylococcus pettenkoferi strain FDAARGOS_1071

Toxin (Protein)


Gene name TsdT Uniprot ID -
Locus tag I6I28_RS02550 Protein ID WP_049405730.1
Coordinates 507058..507264 (-) Length 69 a.a.

Antitoxin (Protein)


Gene name TsdA Uniprot ID -
Locus tag I6I28_RS02555 Protein ID WP_049405729.1
Coordinates 507286..507570 (-) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I28_RS02530 502500..503864 - 1365 WP_049405735.1 UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D- alanine ligase -
I6I28_RS02535 503876..504946 - 1071 WP_049405733.1 D-alanine--D-alanine ligase -
I6I28_RS02540 505173..506366 + 1194 WP_103369936.1 rod shape-determining protein RodA -
I6I28_RS02545 506664..506804 - 141 WP_088606361.1 hypothetical protein -
I6I28_RS02550 507058..507264 - 207 WP_049405730.1 hypothetical protein Toxin
I6I28_RS02555 507286..507570 - 285 WP_049405729.1 copper-sensing transcriptional repressor CsoR Antitoxin
I6I28_RS02560 507730..509202 + 1473 WP_103369942.1 cardiolipin synthase -
I6I28_RS02565 509252..509929 + 678 WP_103369935.1 HD domain-containing protein -
I6I28_RS02570 510067..510933 - 867 WP_049405723.1 membrane protein insertase YidC -
I6I28_RS02575 511013..511663 - 651 WP_186311604.1 thiamine phosphate synthase -
I6I28_RS02580 511660..512451 - 792 WP_049405720.1 hydroxyethylthiazole kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Metal-sensitive transcriptional repressor

(11-89)


Sequences

Toxin        


Download         Length: 69 a.a.        Molecular weight: 7651.54 Da        Isoelectric Point: 3.9936

>T183848 WP_049405730.1 NZ_CP066062:c507264-507058 [Staphylococcus pettenkoferi]
METKHVYTETISTQDQIEELKHLLSNMIGVSEVDIDGAKGDITVTFETPANLNAIEKEIYDASYTILY

Download         Length: 207 bp

>T183848 NZ_CP087193:c1077760-1077506 [Pseudomonas sp. B21-019]
ATGCAAACCATCAACTACACCACCGCACGTGCACATCTGGCCGAAACCATGGATCGGGTCAACGAAGACCGTGCCCCATT
GCTGGTTACCCGCCAGAAAGGCGAACCTGTGGTGATGATGTCTCTGGCGGAGTACAACGCTCTCGAAGAGACAGCCTATC
TGCTCCGTTCTCCAGCCAATGCCGAGCGGCTGATCAAATCAATCGGTAACCTGCGAGCAGGGAAGACCAAAGTCAGGCAA
CTTATCGAAGAATGA

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 10837.37 Da        Isoelectric Point: 6.4786

>AT183848 WP_049405729.1 NZ_CP066062:c507570-507286 [Staphylococcus pettenkoferi]
MDRAHHSEQTKANLKSRLNRIEGQVRAINRMIDEDVYCDDVLTQIRATRSALNSVATQLLDHHMKGCILNKVNKGEEEEA
MEELLVTFQKLMKD

Download         Length: 285 bp

>AT183848 NZ_CP087193:c1077509-1077255 [Pseudomonas sp. B21-019]
ATGAATATCGAGTTCACTCCTGAAGGCTGGGACGACTATTTGTGGTTTCAGCAAAACGATAAGGCCGGGCTCAAACGAAT
CAACCTACTGATCAAGGCGATCCTGCGTGAGCCCTTCGAAGGTTTGGGGAAACCTGAACCGCTCAAACACAACCTGAGCG
GCCTCTGGTCACGCCGAATCACCTCCGAGCATCGTCTGGTTTATGCAATCGAGAATGGTGAGGTGCGCATCGTGCTTTGC
AGGTATCACTACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References