Detailed information of TA system TA183828

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): TsaAT/-
• Location: 1390990..1391466
• Replicon: chromosome
• Accession: NZ_CP066042
• Organism: Staphylococcus saccharolyticus strain FDAARGOS_1074

Toxin (Protein)

• Gene name: TsaT
• Uniprot ID: -
• Locus tag: I6I31_RS06765
• Protein ID: WP_115313761.1
• Coordinates: 1390990..1391178 (-)
• Length: 63 a.a.

Antitoxin (Protein)

• Gene name: TsaA
• Uniprot ID: -
• Locus tag: I6I31_RS06770
• Protein ID: WP_115313760.1
• Coordinates: 1391209..1391466 (-)
• Length: 86 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6I31_RS06730	1386202..1386273	-	72	WP_126517390.1	epsilon family phenol-soluble modulin	-
I6I31_RS06735	1387017..1387193	+	177	WP_115313768.1	cold-shock protein	-
I6I31_RS06740	1387273..1387848	-	576	WP_165417903.1	hypothetical protein	-
I6I31_RS06745	1388390..1388674	-	285	WP_115313765.1	hypothetical protein	-
I6I31_RS06750	1388778..1389515	-	738	WP_115313764.1	poly-gamma-glutamate hydrolase family protein	-
I6I31_RS06755	1389914..1390147	+	234	WP_115313763.1	hypothetical protein	-
I6I31_RS06760	1390207..1390785	-	579	WP_115313762.1	hypothetical protein	-
I6I31_RS06765	1390990..1391178	-	189	WP_115313761.1	hypothetical protein	Toxin
I6I31_RS06770	1391209..1391466	-	258	WP_115313760.1	hypothetical protein	Antitoxin
I6I31_RS06775	1391914..1392107	+	194	Protein_1316	hypothetical protein	-
I6I31_RS06780	1392099..1392335	-	237	WP_115313759.1	hypothetical protein	-
I6I31_RS06785	1392572..1393144	+	573	WP_185802537.1	phosphoglycerate mutase family protein	-
I6I31_RS06790	1393250..1393756	-	507	WP_115313757.1	GNAT family N-acetyltransferase	-
I6I31_RS06795	1394161..1394583	-	423	WP_115313756.1	organic hydroperoxide resistance protein	-
I6I31_RS06800	1394748..1395464	+	717	WP_115313755.1	type I 3-dehydroquinate dehydratase	-
I6I31_RS06805	1395543..1396085	+	543	WP_115313754.1	nitroreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1378458..1399859	21401

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• PIN domain (4-124)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 63 a.a.
• Molecular weight: 7194.98 Da
• Isoelectric Point: 9.6269

>T183828 WP_115313761.1 NZ_CP066042:c1391178-1390990 [Staphylococcus saccharolyticus]
MSLHFYILLWLAILFIIAGTILLITMLKTKKEERKESYLGFTVIFLIFGIAILIYTLIFGIL

Nucleotide

• Length: 189 bp

>T183828 NZ_CP087188:c317949-317542 [Pseudomonas laurylsulfatiphila]
ATGATCAAGTACATGCTCGATACCAACATCTGCATCTTCACCATCAAGAACAAACCACAGGCGGTACGGGAGGCGTTCAA
CCGTCATCACGGCCAACTGTGCATCAGCGCGATAACGCTGATGGAACTGATCTACGGAGCGGAAAAGTCAGCAGCACCCG
AAAAAAATCTGGCGGTCATCGAGGGCTTTGCTGCCCGACTTGAAGTCCTGCCCTTCGACAACGAAGCAGCAGCGCACACC
GGAATGATTCGATCCGAACTGGCAAAGGCCGGCACCCCCATCGGCCCGTACGACCAAATGATTGCCGGGCACGCACGCTC
ACGCGGATTTATTGTGGTCACCAACAATCTGCGGGAGTTTGAGCGCGTTCCGGGGTTACGCGTGGAAGACTGGGTTCATG
TCGAATGA

Antitoxin

Protein

• Length: 86 a.a.
• Molecular weight: 9892.03 Da
• Isoelectric Point: 3.9522

>AT183828 WP_115313760.1 NZ_CP066042:c1391466-1391209 [Staphylococcus saccharolyticus]
MKLIRINVINVILTILFMAFNVLITYNENIDNNLWLVPGLIICGITLLTSLTIAIVYTDLFSEILFFINIILALYYIYPI
LYEFI

Nucleotide

• Length: 258 bp

>AT183828 NZ_CP087188:c318179-317949 [Pseudomonas laurylsulfatiphila]
ATGGAACAGACAACCCTTTTCATGAGCAATCGAAGCCAGGCCGTTCGCCTGCCAAAAGCCGTGGCCATGCCAAGCGACGT
GAAACGGGTCGACGTCGTCGCCGTCGGCAGAGCCCGCATCATCACGCCCGCTGGTGAAACCTGGGACAGTTGGTTCGATG
GTGAAAGCGTCACTGCAGACTTCATGACCGACCGCGAGCAACCTGCCGAGCAGGAGCGTGAGTCGTTCTGA