Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 3485827..3486061 Replicon chromosome
Accession NZ_CP066032
Organism Escherichia coli strain FDAARGOS_1059

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 3485957..3486060 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 3485827..3486061 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I16_RS17050 3482382..3483044 - 663 WP_000944256.1 exodeoxyribonuclease X -
I6I16_RS17055 3483068..3483724 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
I6I16_RS17060 3483826..3484056 - 231 WP_000916763.1 DNA polymerase III subunit theta -
I6I16_RS17065 3484195..3484569 + 375 WP_000204700.1 CopC domain-containing protein YobA -
I6I16_RS17070 3484573..3485445 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
I6I16_RS17075 3485458..3485799 + 342 WP_000976472.1 YebY family protein -
- 3485827..3486061 - 235 - - Antitoxin
- 3485957..3486060 + 104 - - Toxin
I6I16_RS17080 3486192..3487268 - 1077 WP_001189084.1 phage integrase Arm DNA-binding domain-containing protein -
I6I16_RS17085 3487234..3487515 - 282 WP_001311878.1 excisionase -
I6I16_RS17090 3487622..3487810 - 189 WP_001356607.1 DUF1187 family protein -
- 3487626..3487804 + 179 NuclAT_0 - -
- 3487626..3487804 + 179 NuclAT_0 - -
- 3487626..3487804 + 179 NuclAT_0 - -
- 3487626..3487804 + 179 NuclAT_0 - -
I6I16_RS17095 3487803..3487997 - 195 WP_010989194.1 type I toxin-antitoxin system endodeoxyribonuclease toxin RalR -
I6I16_RS17100 3488061..3489113 - 1053 WP_001004417.1 recombinase RecT -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3463808..3543955 80147


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T183800 NZ_CP066032:3485957-3486060 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTTTTTTT

Antitoxin


Download         Length: 235 bp

>AT183800 NZ_CP066032:c3486061-3485827 [Escherichia coli]
TAAAAAAAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCA
TTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACGACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAAT
AAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCGTTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References