Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1861537..1862210 Replicon chromosome
Accession NZ_CP066026
Organism Brevundimonas diminuta strain FDAARGOS_1026

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I6H83_RS09215 Protein ID WP_003165189.1
Coordinates 1861788..1862210 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I6H83_RS09210 Protein ID WP_003165190.1
Coordinates 1861537..1861791 (+) Length 85 a.a.

Genomic Context

I6H83_RS09200I6H83_RS09205I6H83_RS09210I6H83_RS09215I6H83_RS09220I6H83_RS09225I6H83_RS09180I6H83_RS09185I6H83_RS09190I6H83_RS09195I6H83_RS09230I6H83_RS09235I6H83_RS09240
Location: 1859837..1860397 (561 bp)
Type: Others
Protein ID: WP_003165192.1
Location: 1860397..1861347 (951 bp)
Type: Others
Protein ID: WP_040345555.1
Location: 1861537..1861791 (255 bp)
Type: Antitoxin
Protein ID: WP_003165190.1
Location: 1861788..1862210 (423 bp)
Type: Toxin
Protein ID: WP_003165189.1
Location: 1862419..1862901 (483 bp)
Type: Others
Protein ID: WP_128720135.1
Location: 1862943..1864315 (1373 bp)
Type: Others
Protein ID: WP_095046155.1
Location: 1856922..1857446 (525 bp)
Type: Others
Protein ID: WP_128720136.1
Location: 1857777..1857854 (78 bp)
Type: Others
Protein ID: Protein_1811
Location: 1857893..1858348 (456 bp)
Type: Others
Protein ID: WP_003169270.1
Location: 1858468..1859400 (933 bp)
Type: Others
Protein ID: WP_003165193.1
Location: 1864312..1865436 (1125 bp)
Type: Others
Protein ID: WP_128720134.1
Location: 1865436..1866065 (630 bp)
Type: Others
Protein ID: WP_157683871.1
Location: 1866145..1866279 (135 bp)
Type: Others
Protein ID: WP_128720133.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I6H83_RS091801856922..1857446-525WP_128720136.1hypothetical protein-
I6H83_RS091851857777..1857854-78Protein_1811nucleotidyl transferase AbiEii/AbiGii toxin family protein-
I6H83_RS091901857893..1858348-456WP_003169270.1helix-turn-helix domain-containing protein-
I6H83_RS091951858468..1859400-933WP_003165193.1AraC family transcriptional regulator-
I6H83_RS092001859837..1860397+561WP_003165192.1sigma-70 family RNA polymerase sigma factor-
I6H83_RS092051860397..1861347+951WP_040345555.1FecR domain-containing protein-
I6H83_RS092101861537..1861791+255WP_003165190.1hypothetical proteinAntitoxin
I6H83_RS092151861788..1862210+423WP_003165189.1type II toxin-antitoxin system VapC family toxinToxin
I6H83_RS092201862419..1862901+483WP_128720135.1STN domain-containing protein-
I6H83_RS092251862943..1864315+1373WP_095046155.1IS3 family transposase-
I6H83_RS092301864312..1865436-1125WP_128720134.1hypothetical protein-
I6H83_RS092351865436..1866065-630WP_157683871.1lasso peptide biosynthesis B2 protein-
I6H83_RS092401866145..1866279-135WP_128720133.1benenodin family lasso peptide-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideIntegrative and Conjugative Element--1734348..1901784167436


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14745.03 Da        Isoelectric Point: 6.4815

>T183786 WP_003165189.1 NZ_CP066026:1861788-1862210 [Brevundimonas diminuta]
MILLDTNVISETMRPEPHPDVVRWLDEQAAETLYLSSVTVAEMLFGIGVLPAGRRKDRLAAAVDGIVALFGDRILAFDLV
AARHHAALAVKARTAGKGFPTPDGYIAAIAAAHGFAVATRDVSAFAAAGLPVMNPWASPN

Download         Length: 423 bp

>T183786 NZ_CP087182:c761967-761677 [Pseudomonas protegens]
ATGCGCACCCCAGTGACCCGCTTCGACGCGGCGGAGTACCTCAAGACCCCTGAAGACATGGTCGCCTACCTCGACGCCTG
CTTCGAGGAAGACACCGGCGACGGCGTGCTGATCCGCGCCGCACTCAACGACATCGCCCGTGCCCGCGGCATGACCCAGG
TCGCCCGAGACACCGGCCTGGGCCGCGAAAGCCTGTACAAGGCCCTCGGCAGCCAGGGCAACCCGGAGTTCGCGACTATC
ATCAAGGTGATGAAGGCCCTGGGGTTGAAGATCAACGTCAGCAACGCCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9159.40 Da        Isoelectric Point: 11.3030

>AT183786 WP_003165190.1 NZ_CP066026:1861537-1861791 [Brevundimonas diminuta]
MAAVTIRNLSEETHRALKLRAASHGRSAEAEIRDILERAVRPAKRVRLGSAMAAAGRQAGVTNADVEALEQHRDRKPASP
MSFE

Download         Length: 255 bp

>AT183786 NZ_CP087182:c762273-761971 [Pseudomonas protegens]
ATGTTCGTTTTCGAGCAGACTCCTGAGTTCAGCCGCTGGCTGCTGAACCTGAAGGACCCGCAAGGGAAAACCCGTGTACT
GGCCAGGATCCGTGCCGCACAGCTGGGCCGTTTTGGCGACTGCGAACCTGTGGGCGAAGGCGTCCACGAAATGCGCATCC
ACCGCGGCCCGGGTTACCGGGTGTACTTCTCGCGCCGCGGCAAAGTGATCTACCTGCTGTTGATCGGCGGCGACAAGGCC
ACCCAGAAACGCGATATCCAACGGGCCAGGCAACTGGCCTGCGACCTCAAGAGCGAGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References