Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-StbC
Location 1861537..1862210 Replicon chromosome
Accession NZ_CP066026
Organism Brevundimonas diminuta strain FDAARGOS_1026

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I6H83_RS09215 Protein ID WP_003165189.1
Coordinates 1861788..1862210 (+) Length 141 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I6H83_RS09210 Protein ID WP_003165190.1
Coordinates 1861537..1861791 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6H83_RS09180 1856922..1857446 - 525 WP_128720136.1 hypothetical protein -
I6H83_RS09185 1857777..1857854 - 78 Protein_1811 nucleotidyl transferase AbiEii/AbiGii toxin family protein -
I6H83_RS09190 1857893..1858348 - 456 WP_003169270.1 helix-turn-helix domain-containing protein -
I6H83_RS09195 1858468..1859400 - 933 WP_003165193.1 AraC family transcriptional regulator -
I6H83_RS09200 1859837..1860397 + 561 WP_003165192.1 sigma-70 family RNA polymerase sigma factor -
I6H83_RS09205 1860397..1861347 + 951 WP_040345555.1 FecR domain-containing protein -
I6H83_RS09210 1861537..1861791 + 255 WP_003165190.1 hypothetical protein Antitoxin
I6H83_RS09215 1861788..1862210 + 423 WP_003165189.1 type II toxin-antitoxin system VapC family toxin Toxin
I6H83_RS09220 1862419..1862901 + 483 WP_128720135.1 STN domain-containing protein -
I6H83_RS09225 1862943..1864315 + 1373 WP_095046155.1 IS3 family transposase -
I6H83_RS09230 1864312..1865436 - 1125 WP_128720134.1 hypothetical protein -
I6H83_RS09235 1865436..1866065 - 630 WP_157683871.1 lasso peptide biosynthesis B2 protein -
I6H83_RS09240 1866145..1866279 - 135 WP_128720133.1 benenodin family lasso peptide -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1734348..1901784 167436


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(2-121)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 141 a.a.        Molecular weight: 14745.03 Da        Isoelectric Point: 6.4815

>T183786 WP_003165189.1 NZ_CP066026:1861788-1862210 [Brevundimonas diminuta]
MILLDTNVISETMRPEPHPDVVRWLDEQAAETLYLSSVTVAEMLFGIGVLPAGRRKDRLAAAVDGIVALFGDRILAFDLV
AARHHAALAVKARTAGKGFPTPDGYIAAIAAAHGFAVATRDVSAFAAAGLPVMNPWASPN

Download         Length: 423 bp

>T183786 NZ_CP087182:c761967-761677 [Pseudomonas protegens]
ATGCGCACCCCAGTGACCCGCTTCGACGCGGCGGAGTACCTCAAGACCCCTGAAGACATGGTCGCCTACCTCGACGCCTG
CTTCGAGGAAGACACCGGCGACGGCGTGCTGATCCGCGCCGCACTCAACGACATCGCCCGTGCCCGCGGCATGACCCAGG
TCGCCCGAGACACCGGCCTGGGCCGCGAAAGCCTGTACAAGGCCCTCGGCAGCCAGGGCAACCCGGAGTTCGCGACTATC
ATCAAGGTGATGAAGGCCCTGGGGTTGAAGATCAACGTCAGCAACGCCTGA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9159.40 Da        Isoelectric Point: 11.3030

>AT183786 WP_003165190.1 NZ_CP066026:1861537-1861791 [Brevundimonas diminuta]
MAAVTIRNLSEETHRALKLRAASHGRSAEAEIRDILERAVRPAKRVRLGSAMAAAGRQAGVTNADVEALEQHRDRKPASP
MSFE

Download         Length: 255 bp

>AT183786 NZ_CP087182:c762273-761971 [Pseudomonas protegens]
ATGTTCGTTTTCGAGCAGACTCCTGAGTTCAGCCGCTGGCTGCTGAACCTGAAGGACCCGCAAGGGAAAACCCGTGTACT
GGCCAGGATCCGTGCCGCACAGCTGGGCCGTTTTGGCGACTGCGAACCTGTGGGCGAAGGCGTCCACGAAATGCGCATCC
ACCGCGGCCCGGGTTACCGGGTGTACTTCTCGCGCCGCGGCAAAGTGATCTACCTGCTGTTGATCGGCGGCGACAAGGCC
ACCCAGAAACGCGATATCCAACGGGCCAGGCAACTGGCCTGCGACCTCAAGAGCGAGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References