183785

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/Txe-RelB
Location 1613910..1614439 Replicon chromosome
Accession NZ_CP066024
Organism Enterococcus casseliflavus strain FDAARGOS_998

Toxin (Protein)


Gene name relE Uniprot ID A0A7T4GDV7
Locus tag I6H55_RS07985 Protein ID WP_010748738.1
Coordinates 1614173..1614439 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID A0A377KQM1
Locus tag I6H55_RS07980 Protein ID WP_010748737.1
Coordinates 1613910..1614173 (+) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6H55_RS07965 1609479..1610744 - 1266 WP_010748734.1 glycoside hydrolase family 27 protein -
I6H55_RS07970 1610865..1611764 + 900 WP_010748735.1 AraC family transcriptional regulator -
I6H55_RS07975 1611815..1613755 + 1941 WP_010748736.1 glycoside hydrolase family 127 protein -
I6H55_RS07980 1613910..1614173 + 264 WP_010748737.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
I6H55_RS07985 1614173..1614439 + 267 WP_010748738.1 Txe/YoeB family addiction module toxin Toxin
I6H55_RS07990 1614632..1617463 + 2832 WP_010748739.1 discoidin domain-containing protein -
I6H55_RS07995 1617595..1618248 - 654 WP_170920125.1 ABC transporter permease -
I6H55_RS08000 1618262..1619182 - 921 WP_010748740.1 osmoprotectant ABC transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(22-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(5-69)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10662.12 Da        Isoelectric Point: 10.0683

>T183785 WP_010748738.1 NZ_CP066024:1614173-1614439 [Enterococcus casseliflavus]
MRSDTVTIKNSAKVDLRKIKQSNLKKQFEEVIQALKEDPYMPTQSFEKLRSTHEGRYSRRLNRQHRMVYKVDEENKVVEI
YSAWTHYE

Download         Length: 267 bp

>T183785 NZ_CP087182:298600-298782 [Pseudomonas protegens]
ATGCGCAGTCGGGAAATGATCAGCAGGATCGAGGCGGATGGTTGGTACTTGGTGGCCGTCAAGGGCAGTCACCATCAGTA
CAAGCATCCTTTCAAGCCGGGCCGCGTGACCATCAGGCACCCGGATACGGATCTGCCCAAAGGCACGCTCAACAGCATCT
TGAAACAGGCGGGCCTGAAATGA

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9958.03 Da        Isoelectric Point: 4.2682

>AT183785 WP_010748737.1 NZ_CP066024:1613910-1614173 [Enterococcus casseliflavus]
MAKTTMNPSTARKNFYQLLKDVNENHTEIEIISDRSGNNAVLIGLGDWRAIQETLFLEQTGTLEKVRDREKDDSGFTDID
DIDWQAL

Download         Length: 264 bp

>AT183785 NZ_CP087182:298812-299213 [Pseudomonas protegens]
ATGAAATTCCCGGTGGTTCTGCACAAGGATGCCGACTCCGAATATGGGGTGACAGTTCCGGATGTACCGGGCTGCCATTC
TGCCGGCCCGACGGTTTCCCTGGCGTTCGAGAACATCAAGGAAGCGCTGTCCCTGCACTACGAGGGCCTGGTGGCGGACG
GCGAGCCCTTGCCCCAGGTGCATGAGATTGACGATCACCTGGACAACCCCGACTACGCCGGTGGCGTATGGGGCGTGGTG
GAGTTCGACGTGACGCCCTACTTCGGCAAGTCGGTGCGCTTCAACGCCACCCTGCCGGAGCAATTGCTGGAGCGCATCGA
CCAGAGGGTCGAACGCGATCAGCGCTACCGTTCGCGTTCCGGGTTCCTCGCCGCTGCGGCGCTGCGCGAGCTCTCTGCCT
GA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7T4GDV7

Antitoxin

Source ID Structure
AlphaFold DB A0A377KQM1

References