Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 338298..338786 Replicon chromosome
Accession NZ_CP066022
Organism Fusobacterium canifelinum strain FDAARGOS_999

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag I6H56_RS01585 Protein ID WP_124797104.1
Coordinates 338298..338561 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag I6H56_RS01590 Protein ID WP_088389127.1
Coordinates 338562..338786 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6H56_RS01560 333670..334209 - 540 WP_147367458.1 TlpA family protein disulfide reductase -
I6H56_RS01565 334231..335688 - 1458 WP_198480804.1 HD domain-containing protein -
I6H56_RS01570 335750..336238 - 489 WP_198480805.1 hypothetical protein -
I6H56_RS01575 336406..337833 - 1428 WP_198480806.1 transposase -
I6H56_RS01580 337846..338118 - 273 Protein_289 IS200/IS605 family transposase -
I6H56_RS01585 338298..338561 - 264 WP_124797104.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6H56_RS01590 338562..338786 - 225 WP_088389127.1 hypothetical protein Antitoxin
I6H56_RS01595 338856..340211 - 1356 WP_198480807.1 sodium:alanine symporter family protein -
I6H56_RS01600 340339..341814 - 1476 WP_198480808.1 cobyric acid synthase -
I6H56_RS01605 341958..342209 - 252 WP_198480809.1 hypothetical protein -
I6H56_RS01610 342372..343439 + 1068 WP_198480810.1 NCS2 family permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 330708..338786 8078


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin

Protein of unknown function DUF6290

(1-72)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10573.46 Da        Isoelectric Point: 10.0180

>T183783 WP_124797104.1 NZ_CP066022:c338561-338298 [Fusobacterium canifelinum]
MYKVYFDKKVEKDFKKLDKNVLKLILDWIENNLENIEEPRSKGKALVGNLKDYWRYRIGDYRLITKIDDGKLLIIALELK
HRKEVYK

Download         Length: 264 bp

>T183783 NZ_CP087181:4389426-4389719 [Pseudomonas sp. B21-031]
ATGACTGAAACATTTTTTGAGTTCGATGCGGCCGATTACCTGACCACTCCGCAAGCCATCGCTCAATTCATGTCCGATGC
GCTGGAAACGGGTGATGCCAGCTACGTGGCCAAAGCCGTTGGCGTAGTGGCTCGTGCAAAAGGGATGAGCGATCTGGCGA
AAGAAACCGGCTTGTCTCGTGAGCAACTTTACCGATCGTTCAGCGAACACGGCAATCCGACCCTTAAATCGTTCCTCGCA
GTCATGAAGGCGTTGGGCATAGACATGACGGCAAAACCTCACCTTGCACACTAA

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8686.02 Da        Isoelectric Point: 5.8834

>AT183783 WP_088389127.1 NZ_CP066022:c338786-338562 [Fusobacterium canifelinum]
MSNITLRLTDEEREILNSVAHLYGDKLSTAIKTILFEKIEEDYNLKIVKDFEKREKENKVELVSLSDFRKKLGV

Download         Length: 225 bp

>AT183783 NZ_CP087181:4389131-4389433 [Pseudomonas sp. B21-031]
ATGAAGAAGATCGAATCCAGCAGTTTCAGACATTGGGTGCATGGGCTCCGGGACGAAATGGCGCGTATCCGGATCATTGC
TCGTATTAACCGTTTGATGGAGGGCCTGTCTGGTGACGTCTCAGCAGTTGGCCACGGCGTGAGTGAACTCCGAATTCACC
ATGGTCCGGGCTACCGGGTGTACTTTCACCAAGCAGGCGATACGTTGGTAATACTGCTTTGCGGCGGGGACAAGAGCAGC
CAGCGGCGGGACATCAAAGCGGCTCACGAAATCCTGCGTTCCTGGAGGATGCAAAATGACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References