Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/-
Location 3452537..3453190 Replicon chromosome
Accession NZ_CP066016
Organism Acinetobacter baumannii strain FDAARGOS_1036

Toxin (Protein)


Gene name cptA Uniprot ID B0V6V2
Locus tag I6H93_RS16585 Protein ID WP_000931890.1
Coordinates 3452801..3453190 (+) Length 130 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID V5V966
Locus tag I6H93_RS16580 Protein ID WP_001288210.1
Coordinates 3452537..3452794 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6H93_RS16560 3448053..3449060 + 1008 WP_000198631.1 DNA-directed RNA polymerase subunit alpha -
I6H93_RS16565 3449079..3449456 + 378 WP_001216378.1 50S ribosomal protein L17 -
I6H93_RS16570 3449637..3451127 + 1491 WP_000415133.1 NAD(P)/FAD-dependent oxidoreductase -
I6H93_RS16575 3451177..3452349 - 1173 WP_001190546.1 acyl-CoA dehydrogenase family protein -
I6H93_RS16580 3452537..3452794 + 258 WP_001288210.1 succinate dehydrogenase assembly factor 2 Antitoxin
I6H93_RS16585 3452801..3453190 + 390 WP_000931890.1 membrane protein Toxin
I6H93_RS16590 3453960..3455045 + 1086 WP_000049106.1 hypothetical protein -
I6H93_RS16595 3455123..3455689 + 567 WP_000651536.1 rhombosortase -
I6H93_RS16600 3455877..3458072 + 2196 WP_001158905.1 TRAP transporter large permease subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Flavinator of succinate dehydrogenase

(10-82)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 15649.98 Da        Isoelectric Point: 10.4623

>T183771 WP_000931890.1 NZ_CP066016:3452801-3453190 [Acinetobacter baumannii]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY

Download         Length: 390 bp

>T183771 NZ_CP087177:4924535-4924789 [Pseudomonas moraviensis]
ATGCAAACCATCAACTACACCACCGCCCGTGCGCATTTGGCCGAGACGATGGACCGTGTCAATGAAGATCGTGCGCCGCT
ATTGGTCACTCGGCAGAAAGGTGAACCAGTAGTGATGATGTCTTTGGCCGAATACAACGCATTGGAAGAAACAGCGTATT
TGCTTCGCTCCCCCGCCAACGCCGAACGGCTGATGAAATCCATCGGTGAGTTACGCGCCGGCAAAGCCAAAGTCAGGCAA
TTGATCGAAGAATGA

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 10318.77 Da        Isoelectric Point: 4.6150

>AT183771 WP_001288210.1 NZ_CP066016:3452537-3452794 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG

Download         Length: 258 bp

>AT183771 NZ_CP087177:4924786-4925040 [Pseudomonas moraviensis]
ATGAAAATCGAGTTCACGCCCACAGGCTGGGAAGACTATTTGTGGTTTCAGCAAAACGACAAGGCTGGGCTCAAGCGCAT
CAATCTTCTGATCAAAGCAATCAAGCGCGAACCGTTTGAGGGTGTCGGTAAACCAGAGGCGCTCAAACATAATATGAGCG
GCCTCTGGTCACGCCGAGTAACGGCCGAACATCGTCTGGTGTACAGGGTTGAGGACGGCGAAATCTGCGTCATCAGTTGC
CGGTATCACTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0J1A4U0

Antitoxin

Source ID Structure
AlphaFold DB A0A7U4BQM7

References