Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | IV | Classification (family/domain) | cptAB/- |
Location | 3452537..3453190 | Replicon | chromosome |
Accession | NZ_CP066016 | ||
Organism | Acinetobacter baumannii strain FDAARGOS_1036 |
Toxin (Protein)
Gene name | cptA | Uniprot ID | B0V6V2 |
Locus tag | I6H93_RS16585 | Protein ID | WP_000931890.1 |
Coordinates | 3452801..3453190 (+) | Length | 130 a.a. |
Antitoxin (Protein)
Gene name | cptB | Uniprot ID | V5V966 |
Locus tag | I6H93_RS16580 | Protein ID | WP_001288210.1 |
Coordinates | 3452537..3452794 (+) | Length | 86 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
I6H93_RS16560 | 3448053..3449060 | + | 1008 | WP_000198631.1 | DNA-directed RNA polymerase subunit alpha | - |
I6H93_RS16565 | 3449079..3449456 | + | 378 | WP_001216378.1 | 50S ribosomal protein L17 | - |
I6H93_RS16570 | 3449637..3451127 | + | 1491 | WP_000415133.1 | NAD(P)/FAD-dependent oxidoreductase | - |
I6H93_RS16575 | 3451177..3452349 | - | 1173 | WP_001190546.1 | acyl-CoA dehydrogenase family protein | - |
I6H93_RS16580 | 3452537..3452794 | + | 258 | WP_001288210.1 | succinate dehydrogenase assembly factor 2 | Antitoxin |
I6H93_RS16585 | 3452801..3453190 | + | 390 | WP_000931890.1 | membrane protein | Toxin |
I6H93_RS16590 | 3453960..3455045 | + | 1086 | WP_000049106.1 | hypothetical protein | - |
I6H93_RS16595 | 3455123..3455689 | + | 567 | WP_000651536.1 | rhombosortase | - |
I6H93_RS16600 | 3455877..3458072 | + | 2196 | WP_001158905.1 | TRAP transporter large permease subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 130 a.a. Molecular weight: 15649.98 Da Isoelectric Point: 10.4623
>T183771 WP_000931890.1 NZ_CP066016:3452801-3453190 [Acinetobacter baumannii]
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY
MLNHLNFKLKYSRFSIIFQFFIGLSLAILFYQLMPLLWWLVVISLLFISFIFFLKRPQLAKIAYLDKKLWSLAYHSQNTI
SRVKILKIIDYQIFIVIYFEGHKTLTSIIWFDQMSLAEWKKLKTLEKLY
Download Length: 390 bp
>T183771 NZ_CP087177:4924535-4924789 [Pseudomonas moraviensis]
ATGCAAACCATCAACTACACCACCGCCCGTGCGCATTTGGCCGAGACGATGGACCGTGTCAATGAAGATCGTGCGCCGCT
ATTGGTCACTCGGCAGAAAGGTGAACCAGTAGTGATGATGTCTTTGGCCGAATACAACGCATTGGAAGAAACAGCGTATT
TGCTTCGCTCCCCCGCCAACGCCGAACGGCTGATGAAATCCATCGGTGAGTTACGCGCCGGCAAAGCCAAAGTCAGGCAA
TTGATCGAAGAATGA
ATGCAAACCATCAACTACACCACCGCCCGTGCGCATTTGGCCGAGACGATGGACCGTGTCAATGAAGATCGTGCGCCGCT
ATTGGTCACTCGGCAGAAAGGTGAACCAGTAGTGATGATGTCTTTGGCCGAATACAACGCATTGGAAGAAACAGCGTATT
TGCTTCGCTCCCCCGCCAACGCCGAACGGCTGATGAAATCCATCGGTGAGTTACGCGCCGGCAAAGCCAAAGTCAGGCAA
TTGATCGAAGAATGA
Antitoxin
Download Length: 86 a.a. Molecular weight: 10318.77 Da Isoelectric Point: 4.6150
>AT183771 WP_001288210.1 NZ_CP066016:3452537-3452794 [Acinetobacter baumannii]
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG
MSEEMTLEERKVIYRARRGLKEIDVYFDPYVKNYYLKADPAEKALFAELVEQEDPDLLDWFMEVSEPPRTELRDFIYKLK
HYVHG
Download Length: 258 bp
>AT183771 NZ_CP087177:4924786-4925040 [Pseudomonas moraviensis]
ATGAAAATCGAGTTCACGCCCACAGGCTGGGAAGACTATTTGTGGTTTCAGCAAAACGACAAGGCTGGGCTCAAGCGCAT
CAATCTTCTGATCAAAGCAATCAAGCGCGAACCGTTTGAGGGTGTCGGTAAACCAGAGGCGCTCAAACATAATATGAGCG
GCCTCTGGTCACGCCGAGTAACGGCCGAACATCGTCTGGTGTACAGGGTTGAGGACGGCGAAATCTGCGTCATCAGTTGC
CGGTATCACTATTGA
ATGAAAATCGAGTTCACGCCCACAGGCTGGGAAGACTATTTGTGGTTTCAGCAAAACGACAAGGCTGGGCTCAAGCGCAT
CAATCTTCTGATCAAAGCAATCAAGCGCGAACCGTTTGAGGGTGTCGGTAAACCAGAGGCGCTCAAACATAATATGAGCG
GCCTCTGGTCACGCCGAGTAACGGCCGAACATCGTCTGGTGTACAGGGTTGAGGACGGCGAAATCTGCGTCATCAGTTGC
CGGTATCACTATTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0J1A4U0 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A7U4BQM7 |