Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-pasA/RelE-HTH
Location 2075454..2075937 Replicon chromosome
Accession NZ_CP066015
Organism Kytococcus sedentarius strain FDAARGOS_1061

Toxin (Protein)


Gene name relE Uniprot ID C7NFN2
Locus tag I6I18_RS09825 Protein ID WP_015780317.1
Coordinates 2075454..2075720 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag I6I18_RS09830 Protein ID WP_015780318.1
Coordinates 2075704..2075937 (-) Length 78 a.a.

Genomic Context

I6I18_RS09815I6I18_RS09820I6I18_RS09840I6I18_RS09845I6I18_RS09850I6I18_RS09800I6I18_RS09805I6I18_RS09810I6I18_RS09825I6I18_RS09830I6I18_RS09835I6I18_RS09855I6I18_RS09860
Location: 2075164..2075310 (147 bp)
Type: Others
Protein ID: WP_169307799.1
Location: 2075315..2075452 (138 bp)
Type: Others
Protein ID: WP_015780316.1
Location: 2076704..2077603 (900 bp)
Type: Others
Protein ID: WP_015780320.1
Location: 2077823..2078410 (588 bp)
Type: Others
Protein ID: WP_015780321.1
Location: 2078607..2079410 (804 bp)
Type: Others
Protein ID: WP_143827386.1
Location: 2071921..2073054 (1134 bp)
Type: Others
Protein ID: Protein_1918
Location: 2073091..2074440 (1350 bp)
Type: Others
Protein ID: WP_015779415.1
Location: 2074502..2074687 (186 bp)
Type: Others
Protein ID: Protein_1920
Location: 2075454..2075720 (267 bp)
Type: Toxin
Protein ID: WP_015780317.1
Location: 2075704..2075937 (234 bp)
Type: Antitoxin
Protein ID: WP_015780318.1
Location: 2076029..2076541 (513 bp)
Type: Others
Protein ID: WP_169307800.1
Location: 2079425..2079778 (354 bp)
Type: Others
Protein ID: WP_015780323.1
Location: 2079782..2080639 (858 bp)
Type: Others
Protein ID: WP_172465380.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I6I18_RS098002071921..2073054-1134Protein_1918ISL3 family transposase-
I6I18_RS098052073091..2074440-1350WP_015779415.1IS256 family transposase-
I6I18_RS098102074502..2074687-186Protein_1920ISL3 family transposase-
I6I18_RS098152075164..2075310+147WP_169307799.1hypothetical protein-
I6I18_RS098202075315..2075452+138WP_015780316.1hypothetical protein-
I6I18_RS098252075454..2075720-267WP_015780317.1type II toxin-antitoxin system RelE/ParE family toxinToxin
I6I18_RS098302075704..2075937-234WP_015780318.1ribbon-helix-helix protein, CopG familyAntitoxin
I6I18_RS098352076029..2076541-513WP_169307800.1hypothetical protein-
I6I18_RS098402076704..2077603+900WP_015780320.11,4-dihydroxy-2-naphthoate polyprenyltransferase-
I6I18_RS098452077823..2078410+588WP_015780321.1hypothetical protein-
I6I18_RS098502078607..2079410+804WP_143827386.1hypothetical protein-
I6I18_RS098552079425..2079778-354WP_015780323.1DUF4229 domain-containing protein-
I6I18_RS098602079782..2080639-858WP_172465380.1c-type cytochrome biogenesis protein CcsB-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-86)

Antitoxin

Ribbon-helix-helix protein, CopG

(5-42)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 9964.50 Da        Isoelectric Point: 8.0650

>T183767 WP_015780317.1 NZ_CP066015:c2075720-2075454 [Kytococcus sedentarius]
MAWTVEVSATARKALKKLDPPVARRIVRFLRELEALDDPRARGKALTGVLSGLWRYRVGDHRVICDVDDEVLVVHVIEVG
HRSSVYDD

Download         Length: 267 bp

>T183767 NZ_CP087177:c1767543-1766968 [Pseudomonas moraviensis]
GTGAGGCATTCCTCTTTCACTGCTGTATACGATGCATGCGTCTTATATCCGGCCCCTTTGAGAGACTTCCTTATGTGGCT
CGCGTTGTCTGGGCTGTATCGAGCTCGCTGGACTCAGGAAATACACCACGAATGGAAGCGTAACTTATTGAAGAACAGGT
CCGACCTGACCCTCGAACAACTCGATCGCACATCGCAATTGATGAACCTGGCCATTCCAGATGCGTGTATCGATGGCTAT
GAAGACTTGGTGTCAGGTCTGACGCTGCCTGATGAGAACGACCGCCATGTTCTGGCGGCCGCTATCCGATGCGGTGCCGA
TGTAATAGTGACGTTCAACCTGAAAGATTTCCCCTCCTGTCATCTCGCGCCATATGGCATCGAAGCTCAGCACCCGGATG
AGTTTGTGGAAAACCTTTTTCATCTTGATTCGGCTGCCGTCGTCGCTGCGGCCCAAAGCCAGCGACGGCAATTGAAAACG
CCCACTGTGGAGGTGGACAAATATCTTGGCTTTCTCCAGCGGCAAGGCTTGGTCGAATCGGTAAAGGCGTTAGGTAACTA
TCGTGCGATTCTCTGA

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8649.65 Da        Isoelectric Point: 4.6412

>AT183767 WP_015780318.1 NZ_CP066015:c2075937-2075704 [Kytococcus sedentarius]
MTVATSVKLSDETGRKLEQLAAATGRSKSYYLREAVETHIDRLLYEYGIVQRVEDVRAGREATYGLDEVEADLGLDR

Download         Length: 234 bp

>AT183767 NZ_CP087177:c1768007-1767540 [Pseudomonas moraviensis]
ATGCCCACTCCAATTCCTTCCACTACAAATTTGCCAGTTGAACGCGAAGTCAAAGCCGCGATTGAAGGCCAGCGAACCCT
CACCGCTTTCCTCGCCACAGGTTTCGATACCCAGCGAATCCAGATTTTTGATGAGCAGAATGAAGCCCACAGCGTCGAAC
TGCCAACGTCGGCATTGCGCTTGCTAAGCGATATCCTCGCAGCGCTGGCGGAGGGCAACGCTGTGAAGGTCGTGCCGATC
CATGCCGAGCTGACCACTCAAGAAGCTGCCGATCTGCTCAACGTCTCACGTCCGCACATGATCAAACTGCTGGAGAGCGG
TGAGATTTCCTACCACAAAACAGGCAAGCACCGACGTGTGCGTTTTGCCGATCTGATGGAATATAAAACCCGGCGAGACA
CCGCCAGCGAGCAGGCAATGACGCTTCTCGCGGAGCAGGCACAGGCGCTAAGGACAGGATACGAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
AlphaFold DBC7NFN2

Antitoxin

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Source
ID
Structure
No matching records found

References