Detailed information of TA system TA183758

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): vapBC/VapC-VagC
• Location: 62158..62783
• Replicon: plasmid unnamed3
• Accession: NZ_CP066011
• Organism: Salmonella enterica strain FDAARGOS_1067

Toxin (Protein)

• Gene name: vapC
• Uniprot ID: -
• Locus tag: I6I24_RS24520
• Protein ID: WP_000911322.1
• Coordinates: 62385..62783 (+)
• Length: 133 a.a.

Antitoxin (Protein)

• Gene name: vapB
• Uniprot ID: -
• Locus tag: I6I24_RS24515
• Protein ID: WP_000450265.1
• Coordinates: 62158..62385 (+)
• Length: 76 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6I24_RS24515	62158..62385	+	228	WP_000450265.1	toxin-antitoxin system antitoxin VapB	Antitoxin
I6I24_RS24520	62385..62783	+	399	WP_000911322.1	tRNA(fMet)-specific endonuclease VapC	Toxin
I6I24_RS24525	62792..64954	-	2163	WP_000009318.1	type IV conjugative transfer system coupling protein TraD	-
I6I24_RS24530	65331..66062	-	732	WP_000782438.1	complement resistance protein TraT	-
I6I24_RS24535	66098..66592	-	495	WP_010999946.1	entry exclusion protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..93851	93851

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-69)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 133 a.a.
• Molecular weight: 17065.17 Da
• Isoelectric Point: 12.9205

>T183758 WP_000911322.1 NZ_CP066011:62385-62783 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 399 bp

>T183758 NZ_CP087175:c2751865-2751644 [Pseudomonas sp. B21-041]
ATTGAACAATACAATTCCAACGCTTCAGCGGCTCTGCAGCGCAAAGTGGGTGCAGCAACGCAAAGGCTTTCATCAATTCC
CTATGGTTACAGATCCGGTCGAGTACCAGGCACTCGGGAAATGGTGGTCAATCCAAACTATCTACTGGTCTATCGAGTGA
ACGGGCGCATCAAAATCCTGACGTTAGTCCACACCCGACAACAATACCCACGAACCTCATAA

Antitoxin

Protein

• Length: 76 a.a.
• Molecular weight: 9759.25 Da
• Isoelectric Point: 12.6750

>AT183758 WP_000450265.1 NZ_CP066011:62158-62385 [Salmonella enterica]
KKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKKK

Nucleotide

• Length: 228 bp

>AT183758 NZ_CP087175:c2752106-2751912 [Pseudomonas sp. B21-041]
ATGAGCATATTGCTTTCCCCGTTTTATTCTGAGTTCGAATCCGAAGAAGAGGCAGAGAGCTACGATCGCTGGTTTCGTGC
CAAGGTGCAGGCTGCACTGGATGATCCTCGCCCAGGCATTCCCCATGAGGAAGCCATGGTGCGGCTCGACCAACTATTAG
AAGAGAAACGCAAGAATCGACACACTGCCGCTTGA