Detailed information of TA system TA183754

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): rlegTA/AbiEii-AbiEi
• Location: 6220252..6221711
• Replicon: chromosome
• Accession: NZ_CP066006
• Organism: Delftia acidovorans strain FDAARGOS_997

Toxin (Protein)

• Gene name: rlegT
• Uniprot ID: A0A7T4EMS3
• Locus tag: I6H54_RS28335
• Protein ID: WP_034397555.1
• Coordinates: 6220866..6221711 (+)
• Length: 282 a.a.

Antitoxin (Protein)

• Gene name: rlegA
• Uniprot ID: A0A7T4EMP0
• Locus tag: I6H54_RS28330
• Protein ID: WP_034397556.1
• Coordinates: 6220252..6220869 (+)
• Length: 206 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6H54_RS28315	6216511..6217818	+	1308	WP_012202026.1	NCS2 family nucleobase:cation symporter	-
I6H54_RS28320	6218026..6219540	+	1515	WP_034397557.1	acetyl-CoA hydrolase/transferase family protein	-
I6H54_RS28325	6219671..6220144	+	474	WP_012202024.1	hotdog fold thioesterase	-
I6H54_RS28330	6220252..6220869	+	618	WP_034397556.1	AbiEi antitoxin N-terminal domain-containing protein	Antitoxin
I6H54_RS28335	6220866..6221711	+	846	WP_034397555.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
I6H54_RS28340	6221744..6222445	-	702	WP_034397554.1	ABC transporter ATP-binding protein	-
I6H54_RS28345	6222450..6223208	-	759	WP_034397552.1	ABC transporter ATP-binding protein	-
I6H54_RS28350	6223201..6224268	-	1068	WP_034397551.1	branched-chain amino acid ABC transporter permease	-
I6H54_RS28355	6224272..6225144	-	873	WP_013799989.1	branched-chain amino acid ABC transporter permease	-
I6H54_RS28360	6225187..6226350	-	1164	WP_034397549.1	ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (35-259)

Antitoxin

• Transcriptional regulator, AbiEi antitoxin (12-57)

Sequences

Toxin

Protein

• Length: 282 a.a.
• Molecular weight: 31040.76 Da
• Isoelectric Point: 9.0494

>T183754 WP_034397555.1 NZ_CP066006:6220866-6221711 [Delftia acidovorans]
MSRDIAASIRARLKQCADARRQDFNLTLTHYGLERLLYRLSISPHADSYLLKGALLFAIWYEQPHRPTRDADLLGFGLDD
VDSAVSAFRQICRIAVDDGIAFDAASVRGTAIRKEAGYGGVRIDLRATLDGARITLQVDIGFGDAVTPSPQTIRYPVLLD
GLPAPQLRSYPKYTVVAEKLHAICLLGMANTRMKDYFDLWVLMTEGTLDPAELRRATAATFKRRQLALPAGLPAGLSDGF
SSDAAKQAQWAAFLKKNRLATLELAPVVARLREEFQQCGIF

Nucleotide

• Length: 846 bp

>T183754 NZ_CP087175:c709801-709499 [Pseudomonas sp. B21-041]
ATGATCGCTTTTGAACGATCCCGCATATTTTCCGAATGGCTCGACTCCTTGAAAGACATCAAAGGGAAAGGCCGAATCAT
CTCCAGAATTAAAACAGCCGAAAATGGCAACTTCGGTGATTGCGGGTTCGTCGGTGACACTGTTTATGAAATGCGTGTTC
ATTACGGCCCTGGTTACAGGATGTACTTCACACGCAAAGGCGAAGTGATTTATCTGCTGCTGATCGGGGGCGACAAATCG
ACACAAAAAAGAGATATCAAACGCGCCGTGCAGATGGCTCATAACATCGGAAATGAGGAGTAA

Antitoxin

Protein

• Length: 206 a.a.
• Molecular weight: 22054.67 Da
• Isoelectric Point: 9.9117

>AT183754 WP_034397556.1 NZ_CP066006:6220252-6220869 [Delftia acidovorans]
MPAPGSALEQAVLALAEQRPLLRARDLAALGLPTMALSRLVAAGRLERVARGLYSLPGRPLSEHRSLAEVALRVPQGVVC
LLSALRVHGIGTQAPFEVWMAIPHHSPTPRIDQPALRAIRMSGAALSEGVETLQIDGVGVAVFNASKTVADCFKYRNKIG
LDVALEALRDGWAQRKLTADALWHYAAIDRVSNVMRPYLESIAAS

Nucleotide

• Length: 618 bp

>AT183754 NZ_CP087175:c709495-709205 [Pseudomonas sp. B21-041]
ATGAGCGAAGAATTCGCCCGTTTTGACGCCGCCGAGTACCTCAAAACTCCCGAGGACATGGCGGCGTATCTGGATGCCTG
TTTTGACGACGATGAAGGCGACGGCGTCCTTATCCGTGCAGCGCTCAATGACATCGCCCGGGCTCAAGGCATGACACAAG
TGGCGCGGGATGCAGGTTTGGGCCGCGAAAGTCTTTATAAAGCGCTGAGTAGCACTGGCAATCCCGAATTCGCAACTATC
ATGAAAGTCATGAAGGCTCTGGGTTTGCGATTGCATGCCGTAACACTGTGA