Detailed information of TA system TA183746

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relE-parD/RelE-RHH
• Location: 4055768..4056354
• Replicon: chromosome
• Accession: NZ_CP065997
• Organism: Achromobacter deleyi strain FDAARGOS_1050

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: I6I07_RS18420
• Protein ID: WP_198483182.1
• Coordinates: 4055768..4056070 (-)
• Length: 101 a.a.

Antitoxin (Protein)

• Gene name: parD
• Uniprot ID: A0A6J5BC03
• Locus tag: I6I07_RS18425
• Protein ID: WP_054430290.1
• Coordinates: 4056067..4056354 (-)
• Length: 96 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6I07_RS18400	4051510..4052064	+	555	WP_198487587.1	GNAT family N-acetyltransferase	-
I6I07_RS18405	4052074..4052271	+	198	WP_198483179.1	oxidoreductase-like domain-containing protein	-
I6I07_RS18410	4052343..4054739	-	2397	WP_198483180.1	TonB-dependent receptor	-
I6I07_RS18415	4055074..4055601	-	528	WP_198483181.1	sigma-70 family RNA polymerase sigma factor	-
I6I07_RS18420	4055768..4056070	-	303	WP_198483182.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
I6I07_RS18425	4056067..4056354	-	288	WP_054430290.1	hypothetical protein	Antitoxin
I6I07_RS18430	4056525..4056962	-	438	WP_198483183.1	acetyltransferase	-
I6I07_RS18435	4056978..4058717	-	1740	WP_198483184.1	peptidase M14	-
I6I07_RS18440	4058775..4059641	-	867	WP_198483185.1	ABC transporter permease	-
I6I07_RS18445	4059647..4060570	-	924	WP_006385014.1	ABC transporter permease	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-90)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 101 a.a.
• Molecular weight: 11323.85 Da
• Isoelectric Point: 5.1408

>T183746 WP_198483182.1 NZ_CP065997:c4056070-4055768 [Achromobacter deleyi]
VRALRWTPEAIQDREAIYDFIEADNPIAALTLDELLEEKAGRLIDHPGLGRPGRVAGTRELVAHPNYLLIYDVTNDLVRM
LRVLHAARQWPTPDPSSESR

Nucleotide

• Length: 303 bp

>T183746 NZ_CP087171:5115631-5115909 [Pseudomonas atacamensis]
ATGATCAAATCCTTTCAGCACAAAGGCCTTCGTGGCTTCTATGAAACAGGTACGACTCGTGGAATTCGTGCCGACCATGC
AAAACGGCTGTCGCGCATGTTGCAGTTCATGGATCGAGCAACACTTCCCGGCGATCTGGACTTGCCGGGCTGGCGCCTGC
ATCCGTTGAAAGGCGAGCTGAGTGAATACTGGTCGCTCAGCGTTTCAGGCAACTGGCGAGTGATCTTTCGTTTTGTCGGT
TCGGATATCGAATTGGTCGATTATCTGGACTACCACTGA

Antitoxin

Protein

• Length: 96 a.a.
• Molecular weight: 10843.20 Da
• Isoelectric Point: 10.7725

>AT183746 WP_054430290.1 NZ_CP065997:c4056354-4056067 [Achromobacter deleyi]
MSDATFTFRVDEALKNEFAMAAKARDRTGAQLLRDFMREYVQQQQEAAQHDAWFRRQVQAGLDSANAGRLVPAAEVETKF
AARRAATRRRLETPK

Nucleotide

• Length: 288 bp

>AT183746 NZ_CP087171:5115924-5116211 [Pseudomonas atacamensis]
ATGCCCATGCACAACCCGCCACACCCCGGTGAAACCCTGCTGCTGGATGTCTTGCCCGAGCTTGGTATCAGCGTGAGCGA
ATTGGCCCGGCACCTTGGCTTTGCACGCCCGCATCTTTCGCGCGTACTGCACGGACATGCGCCAATCAGCCCGGATCTGG
CAGTACGACTTGAGCGTGCAGGGATCGGCAAGGCGCGCGTTTGGCTAGGCGTCCAAACCGACTACGATCTTTGGCAAGCG
GAGCACCGTGAGCAACCAATGATAGAACCCCTCGCAGCCCACGGCTGA

Structures

Antitoxin

• AlphaFold DB: A0A6J5BC03