Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 1622172..1622941 Replicon chromosome
Accession NZ_CP065980
Organism Staphylococcus felis strain FDAARGOS_1014

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag I6H71_RS07820 Protein ID WP_167389000.1
Coordinates 1622789..1622941 (+) Length 51 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag I6H71_RS07815 Protein ID WP_103208491.1
Coordinates 1622172..1622771 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6H71_RS07795 1617977..1619431 + 1455 WP_103208483.1 ABC transporter substrate-binding protein/permease -
I6H71_RS07800 1619424..1620146 + 723 WP_103208485.1 amino acid ABC transporter ATP-binding protein -
I6H71_RS07805 1620448..1621575 + 1128 WP_103208487.1 tRNA epoxyqueuosine(34) reductase QueG -
I6H71_RS07810 1621578..1622048 + 471 WP_103208489.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
I6H71_RS07815 1622172..1622771 + 600 WP_103208491.1 glucosamine-6-phosphate isomerase Antitoxin
I6H71_RS07820 1622789..1622941 + 153 WP_167389000.1 hypothetical protein Toxin
I6H71_RS07825 1623054..1623452 + 399 WP_103208493.1 hypothetical protein -
I6H71_RS07830 1623615..1625000 + 1386 WP_103208495.1 class II fumarate hydratase -
I6H71_RS07835 1625022..1626548 + 1527 WP_103208497.1 exopolyphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(124-197)


Sequences

Toxin        


Download         Length: 51 a.a.        Molecular weight: 5983.40 Da        Isoelectric Point: 3.9129

>T183738 WP_167389000.1 NZ_CP065980:1622789-1622941 [Staphylococcus felis]
MYQDKKDYDNEMVDGFDDMVELGKEMEQISEENDQEKLNQDHNQAVRSDK

Download         Length: 153 bp

>T183738 NZ_CP087170:3607306-3607593 [Pseudomonas rhodesiae]
ATGGCCGCTGAGTACGAGGTTGAGTGGGATCCGAAGGCACTGAAGGAGTTGCGTAAACTCGACGGAACAATACGCCTCCA
GTTTCTGAAAAAGCTCCAGGAGCGGCAGTCCGGCCCGCGAGTGCCAGGCGATGCGCTTCATGGCATGAAGGACTGCTACA
AGATCAAATTGCGCGGCGCCGGCTACCGACTTGTGTACCGCGTTGAGGATGAGCGAATTGTCATCCTGGTGCTGGCTGTC
GGCAAACGCGAGCGAAGCTCTGTGTATGAGCAGGCGGGGAAGCGGTAG

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22340.43 Da        Isoelectric Point: 5.8847

>AT183738 WP_103208491.1 NZ_CP065980:1622172-1622771 [Staphylococcus felis]
MAMNFKIFKDADTAALYTADIIRKQFNNNPTTIAGIHLNNEDAPVLEALKKSVDDHAVDFSQIHILDYDKKTSYYKALGV
PEKQVHEIAEEEQVESFIEHHAKTKNNKGKLTLQVVTIDQKGYLGVGMKEGILPAREIILVITGDYKADLVKKLYEENGN
TSFIPSTLKQHRMVNVVLDEAAAQGLPEDVRSYFTSLYA

Download         Length: 600 bp

>AT183738 NZ_CP087170:3607029-3607316 [Pseudomonas rhodesiae]
ATGCAAAATATTCTGGCTGATGTGGCCGTCAGCGTATCTGAACTCAAGAAGAACCCCTCCTCCGTCTTGAGCGGCGCCAA
CGGCATGCCTGTGGCTGTGCTGAACCACAACCGCGTTATGGGCTACATGGTTCCAGCGAACGTCTACGAGGCGATGGTTG
AGCGCCTGGACGAACTGGAGCTGGTCCAACTAGTCAAGGCTCGGCTCGATGCTAAAGAAACACCTGTTCGGGTATCTCTG
GACGATCTGATTGGCGAGACAGAGGCAGATATCGCCAATGGCCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References