Detailed information of TA system TA183702

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE(toxin)
• Location: 898869..899362
• Replicon: chromosome
• Accession: NZ_CP065967
• Organism: Pediococcus pentosaceus strain FDAARGOS_1011

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: I6H68_RS04540
• Protein ID: WP_195748888.1
• Coordinates: 899096..899362 (+)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: I6H68_RS04535
• Protein ID: WP_195748887.1
• Coordinates: 898869..899099 (+)
• Length: 77 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I6H68_RS04505	894300..895697	-	1398	WP_195748882.1	phage portal protein	-
I6H68_RS04510	895705..896976	-	1272	WP_195748883.1	PBSX family phage terminase large subunit	-
I6H68_RS04515	896960..897565	-	606	WP_195748884.1	terminase small subunit	-
I6H68_RS04520	897565..897738	-	174	WP_195748885.1	hypothetical protein	-
I6H68_RS04530	898295..898738	-	444	WP_195748886.1	hypothetical protein	-
I6H68_RS04535	898869..899099	+	231	WP_195748887.1	antitoxin	Antitoxin
I6H68_RS04540	899096..899362	+	267	WP_195748888.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
I6H68_RS04545	899644..899862	-	219	WP_195748889.1	hypothetical protein	-
I6H68_RS04550	900278..900514	-	237	WP_195748890.1	hypothetical protein	-
I6H68_RS04555	900507..900815	-	309	WP_198454188.1	hypothetical protein	-
I6H68_RS04560	900994..901179	-	186	WP_195748891.1	hypothetical protein	-
I6H68_RS04565	901172..901549	-	378	WP_198454189.1	hypothetical protein	-
I6H68_RS04570	901704..902168	-	465	WP_195748894.1	hypothetical protein	-
I6H68_RS04575	902319..902741	-	423	WP_195748895.1	single-stranded DNA-binding protein	-
I6H68_RS04580	902734..902886	-	153	WP_195748896.1	hypothetical protein	-
I6H68_RS04585	902904..903164	-	261	WP_195748897.1	hypothetical protein	-
I6H68_RS04590	903133..903834	-	702	WP_195748898.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	872244..919042	46798

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-87)

Antitoxin

• Protein of unknown function DUF6290 (1-71)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10497.94 Da
• Isoelectric Point: 10.4916

>T183702 WP_195748888.1 NZ_CP065967:899096-899362 [Pediococcus pentosaceus]
MSYRLAFTRDVQRSLRKMDKHQSKLIVRWLYQHVDGTDDPRSFGKGLTANRAGQWRYRIGNYRAIVEIEDDRMVVTAINI
GHRRDIYD

Nucleotide

• Length: 267 bp

>T183702 NZ_CP087165:c3795070-3794789 [Pseudomonas sichuanensis]
ATGACCTATAAGCTCGAGTTTCTGCCCTCTGCGTTGAAGGAGTGGGAGAAACTTGGCCATACCGTGCGTGAGCAAGCCAA
GAAGAAACTGCGTGAGCGGCTGGTACTGCCCAGGGTGCCAGCGGACGCGCTGCGCGACTTGCCCAACCACTACAAGATCA
AACTCAAGTCCTCAGGTTATCGACTGGTCTATCGGGTAGAGGATCAGCGAGTCGTTGTGCTGGTGGTGGCGGTAGGCAAG
CGCGAAGGCGCGGCGGCCTATCGCTCTGCTCTGAAGCGCTGA

Antitoxin

Protein

• Length: 77 a.a.
• Molecular weight: 8970.99 Da
• Isoelectric Point: 3.8171

>AT183702 WP_195748887.1 NZ_CP065967:898869-899099 [Pediococcus pentosaceus]
MAMITVRVSDSEKEWLQYMADFYGVTLSELLKNYSMDQLEDEYDQQVADLAHKRWLDDNKQIVSMEDIIDEFGDLS

Nucleotide

• Length: 231 bp

>AT183702 NZ_CP087165:c3795305-3795060 [Pseudomonas sichuanensis]
ATGCAGAACATCTTCGCCGATATCACCGTCAGCGTCTCGGAATTGAAGAAGAATCCCACGGCTGTCATGGCAGGTGCACA
GGGGCAGCCAGTGGCAGTGCTCAATCATAATCGCGTCATGGGCTACATGGTGCCCGCTGAACTCTATGAGGCGATGATGG
AGCAACTGGAAGACATCGAGCTGGCGCAATTGGTCAAGGCACGTGCGCACGAGAAGGGCGTGCCGGTGAAGCTGGATGAC
CTATAA