Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) PumAB/upstrm_HI1419-dnstrm_HI1420
Location 7852..8500 Replicon chromosome
Accession NZ_CP065965
Organism Stenotrophomonas maltophilia strain FDAARGOS_1044

Toxin (Protein)


Gene name PumA Uniprot ID -
Locus tag I6I01_RS00055 Protein ID WP_005407702.1
Coordinates 7852..8157 (+) Length 102 a.a.

Antitoxin (Protein)


Gene name PumB Uniprot ID -
Locus tag I6I01_RS00060 Protein ID WP_005407703.1
Coordinates 8198..8500 (+) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I6I01_RS00025 3806..4597 - 792 WP_169922258.1 zinc-dependent peptidase -
I6I01_RS00030 4564..4842 - 279 WP_005411956.1 hypothetical protein -
I6I01_RS00035 4987..5952 + 966 WP_024956165.1 bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor -
I6I01_RS00040 5949..6680 + 732 WP_005407698.1 type III pantothenate kinase -
I6I01_RS00045 6690..7544 + 855 WP_005411958.1 SPOR domain-containing protein -
I6I01_RS00055 7852..8157 + 306 WP_005407702.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
I6I01_RS00060 8198..8500 + 303 WP_005407703.1 putative addiction module antidote protein Antitoxin
I6I01_RS00065 8758..9057 - 300 WP_143568664.1 hypothetical protein -
I6I01_RS00070 9138..9545 - 408 WP_024956163.1 hypothetical protein -
I6I01_RS00075 10140..10910 + 771 WP_005411960.1 DUF3011 domain-containing protein -
I6I01_RS00080 10935..11282 - 348 WP_024956162.1 hypothetical protein -
I6I01_RS00085 11413..12333 + 921 WP_005407709.1 arginase -
I6I01_RS00090 12494..12631 + 138 WP_005407710.1 entericidin A/B family lipoprotein -
I6I01_RS00095 12839..13060 + 222 WP_004153772.1 CsbD family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(12-90)

Antitoxin

Cro/C1-type helix-turn-helix domain

(43-95)


Sequences

Toxin        


Download         Length: 102 a.a.        Molecular weight: 11444.15 Da        Isoelectric Point: 10.9897

>T183692 WP_005407702.1 NZ_CP065965:7852-8157 [Stenotrophomonas maltophilia]
MKIQRTRQFATWIDALKDVTARARILARIGRLAEGHPGDHRYLADGVSELRIDAGPGYRVYYTQRGRQLVILLVGGDKGS
QQRDIEKAKEIARALRASNWL

Download         Length: 306 bp

>T183692 NZ_CP087160:1838839-1839135 [Pseudomonas sp. CIP-10]
ATGGAAAAGAGAACGCCTCACTGCCCTTTGCATCGGCTGCAAGTGCTATTGAGCCAAGGGAAGGTACGTACCACCCAGGC
GGCGACCCTGGGAGCGCGGTCGCTTGGGCTAGGTCCCTATGACATGTTGGATGTTGTCCGCGGGCTATCGCCAGGTGACT
TCCATAAAAGTATGACGAGCTACAACGATCATCGTATTTGGCAGGATGTCTATCGGGCGCAAACCGCCGTAGGCAGGGTT
TACCTCAAGCTGACGGTGGTCGACGATCTGCTCATCCTATCTTTCAAGGAGCTTTGA

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 10703.27 Da        Isoelectric Point: 7.2780

>AT183692 WP_005407703.1 NZ_CP065965:8198-8500 [Stenotrophomonas maltophilia]
MAIKKKVELEAFDVAEHLHTPKEMAAYLDACIEESDGDSAFIAKALGDIARAQGMSKVARAAGLSRESLYRALSGERSPD
FSTILKVTRALGVRLHASAA

Download         Length: 303 bp

>AT183692 NZ_CP087160:1839137-1839568 [Pseudomonas sp. CIP-10]
ATGAAATGTCCCCTATGTGGAGGAGCGGAGTTGGTTGCGCAGTCGCGAGACATGCCGTATCGCTACAAAGGTGAGGCGAC
CGTCATCCCGGACATCTTTGGTGACTACTGCCCGACGTGTGGCGAGGCGGTACTGGGTATGGACGAGGCCCAGCGTATGA
GTGATCTGATGACGGCGTTTGAGCGCAAGGTCAATGCCGCCGTTGTCGATCCCGGCTTCATTGCTGCCATGCGCAGAAAG
TTCGACCTCGACCAGCGTGAAGCGGGGGAAATCTTCGGTGGTGGGGTCAATGCGTTCTCCCGTTATGAAAACGGCAAGAC
CACCCCGCCAGTGGCGTTGGTGAAACTGCTCAAGCTGCTGGATCGCCATCCAGAACTCTTTGAGGAAGTGCGTACTGATA
ATGGCAGCCAACAAAAAGCCCCCGGCTCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References