Detailed information of TA system TA183651

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 3877318..3877844
• Replicon: chromosome
• Accession: NZ_CP065946
• Organism: Pectobacterium parmentieri strain WC19161

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: JBL47_RS17695
• Protein ID: WP_198481784.1
• Coordinates: 3877557..3877844 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: JBL47_RS17690
• Protein ID: WP_107333021.1
• Coordinates: 3877318..3877557 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JBL47_RS17675	3872546..3873633	+	1088	WP_121264743.1	IS3 family transposase	-
JBL47_RS17680	3873809..3874672	-	864	WP_198481782.1	HNH endonuclease	-
JBL47_RS17685	3874659..3876617	-	1959	WP_198481783.1	AAA family ATPase	-
JBL47_RS17690	3877318..3877557	+	240	WP_107333021.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
JBL47_RS17695	3877557..3877844	+	288	WP_198481784.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
JBL47_RS17700	3877863..3878057	+	195	Protein_3460	hypothetical protein	-
JBL47_RS17705	3878100..3880295	-	2196	WP_198482528.1	TonB-dependent receptor	-
JBL47_RS17710	3880327..3881661	-	1335	WP_103807879.1	NADPH-dependent L-lysine N(6)-monooxygenase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	iutA / iucD / iucC / iucB / iucA	3871434..3890678	19244

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-83)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (3-79)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11244.10 Da
• Isoelectric Point: 10.1695

>T183651 WP_198481784.1 NZ_CP065946:3877557-3877844 [Pectobacterium parmentieri]
MSYFLDFDERALKEWRKLGETVRNQFKKKLADILDAPRIEANKLKGMPDCYKIKLRSAGYRLVYQVQDEKVVVFVVSVGK
RERSEAYDDAIKRLR

Nucleotide

• Length: 288 bp

>T183651 NZ_CP087143:c41044-40733 [Klebsiella pneumoniae]
ATGCACGTAATTTCAAAAGAGCCTTTTGAGGAAGCGGCAAAGCGATATCCCAACGATTCGTTAGCCATTCGGGCGTTGTA
CCGCTTAGTGCGCGAGACGGACTTCTCTTCTCCAGCTGAGATGCTAACTCTGATACCGAGCCTGGATAATTTTAAGTACA
GGAATAAGTGGTGGGTTTTGGATGTAGGGGGCAACAACTTAAGGGTTATCGCCTATATCAATTTCGTAAATAAGCGCTTC
TACGTGAAGCACATCGCAACCCACGCTGATTACGACAAGTTGACCCGCTATTACAGGGAGAACAAAGAATGA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9037.34 Da
• Isoelectric Point: 4.5112

>AT183651 WP_107333021.1 NZ_CP065946:3877318-3877557 [Pectobacterium parmentieri]
MGSINLRIDDDLKTRSYAALEKLGVTPSEALRLTLEYIAENERLPFKQALLSDEDAELVEIVRERLRNPKPVRVTLDDL

Nucleotide

• Length: 240 bp

>AT183651 NZ_CP087143:c40736-40317 [Klebsiella pneumoniae]
ATGATTACCGACACTGCAAAAGCCATTGAAGCAACCAAACAACTCGTAGCTGCCGTCCCCTTCCTAGGGGGCAGTTCTTC
CGAGAGCGATTACCGCGAAGCGATGGAGCTGGTGGATTATCTGATCGAGAACGACGACGAGAACCCACTTATTGACTTCC
TGGCGAGTAAGATTGCCGACTATGAAGATAACAGCCCTCGTTTCGCTGAGTTCAACAAAGCTATTGCTGAAATACCAGTC
GGCGTTGCACTTCTGCGAACCCTGATTGACCAGCACAAGCTGTCTTATTCAGACCTTAAGGATGAGATCGGATCTAAATC
ATTGGTCAGCCAAATCCTGTCAGGGCAGCGCTCTTTGACCATCACTCACATAAAAGCTCTTTCCGCGCGCTTCGGTGTAA
AACCTGAGTGGTTCCTATAA