Detailed information of TA system TA183649

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): ykfI-yfjZ/CbtA-CbeA
• Location: 3377724..3378448
• Replicon: chromosome
• Accession: NZ_CP065946
• Organism: Pectobacterium parmentieri strain WC19161

Toxin (Protein)

• Gene name: ykfI
• Uniprot ID: -
• Locus tag: JBL47_RS15410
• Protein ID: WP_198481706.1
• Coordinates: 3378128..3378448 (+)
• Length: 107 a.a.

Antitoxin (Protein)

• Gene name: yfjZ
• Uniprot ID: -
• Locus tag: JBL47_RS15405
• Protein ID: WP_198481705.1
• Coordinates: 3377724..3378059 (+)
• Length: 112 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
JBL47_RS15375	3373673..3374548	+	876	WP_198481700.1	GTPase family protein	-
JBL47_RS15380	3374918..3375616	+	699	WP_198481701.1	DeoR family transcriptional regulator	-
JBL47_RS15385	3375798..3376367	+	570	WP_198482522.1	hypothetical protein	-
JBL47_RS15390	3376403..3376876	+	474	WP_198481702.1	hypothetical protein	-
JBL47_RS15395	3376893..3377126	+	234	WP_198481703.1	hypothetical protein	-
JBL47_RS15400	3377211..3377684	+	474	WP_198481704.1	DNA repair protein RadC	-
JBL47_RS15405	3377724..3378059	+	336	WP_198481705.1	type IV toxin-antitoxin system YeeU family antitoxin	Antitoxin
JBL47_RS15410	3378128..3378448	+	321	WP_198481706.1	TA system toxin CbtA family protein	Toxin
JBL47_RS15415	3378566..3379399	+	834	WP_198481707.1	DUF4942 domain-containing protein	-
JBL47_RS15420	3379493..3379723	+	231	WP_161545905.1	antitoxin	-
JBL47_RS15425	3379723..3380127	+	405	WP_192459492.1	tRNA(fMet)-specific endonuclease VapC	-
JBL47_RS15430	3380518..3380962	+	445	Protein_3026	DUF4102 domain-containing protein	-
JBL47_RS15435	3381082..3381486	-	405	WP_198481708.1	hypothetical protein	-
JBL47_RS15440	3381946..3382266	-	321	WP_033071068.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3366218..3390659	24441

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• CbtA toxin of type IV toxin-antitoxin system (1-105)

Antitoxin

• Antitoxin CbeA (7-106)

Sequences

Toxin

Protein

• Length: 107 a.a.
• Molecular weight: 12150.90 Da
• Isoelectric Point: 4.6104

>T183649 WP_198481706.1 NZ_CP065946:3378128-3378448 [Pectobacterium parmentieri]
MQTSPAIPPREDNPCPSPIAVWQQLLTYLLEKHYGLTLNDTPFCEENVIQEHIEAGITLVNAVNFLVEKYELVRIDRDGF
NWQEQSPFLTTVDILRARRVTGLLKA

Nucleotide

• Length: 321 bp

>T183649 NZ_CP087142:c5398703-5398320 [Klebsiella pneumoniae]
ATGACCTCCGGATCTGCGCTTTTTGATACCAATATTCTTATTGATTTATTTAGCGGGCGTCGCGAAGCCAAACAGGCGCT
GGAGGCCTGGCCACCGCAGAATGCGATCAGTCTGATTACCTGGATGGAGGTGATGGTTGGCGCTAAAAAATATCACCAGG
AGCAGCGCACGCGAATGGCGCTGAGCACCTTTAATATCATTAACATCTCACAGGATATTGCAGAGCGAAGCGTTGCGCTG
CGGCAGGAGTATAAGCTTAAGCTGCCGGATGCCATCATTCTGGCGACGGCGCAACTCCATCGTCTGGAACTAATTACGCG
GAATACGAAGGATTTTGCCGGTATTCCTGGCGTAGTCACGCCGTACGAAATCCACCCTGAATAA

Antitoxin

Protein

• Length: 112 a.a.
• Molecular weight: 12274.83 Da
• Isoelectric Point: 5.0988

>AT183649 WP_198481705.1 NZ_CP065946:3377724-3378059 [Pectobacterium parmentieri]
MPSSETPEWGLKSTVTPRFGARLVQEGNRLHYLADRASIVGTFSKTETQSLERCFPELIKQLEQKLCTGDLNPHQQGCIT
LHCNEWTCEADTLGSVGYVYIVISPSSATAE

Nucleotide

• Length: 336 bp

>AT183649 NZ_CP087142:c5398945-5398703 [Klebsiella pneumoniae]
ATGATGGCTGAAAGGGATATGGGCAGAATTCTTCTCGATTTATCAGACGATGTCATTCAACGTCTCGATGACCTCAAAGT
GCAGCGTAACATTCCGCGAGCGGAACTGTTACGTGAAGCGGTTGAACAATATCTGGAGAAACAAGATCGAGCTAAAGATA
CCATCTCCAGTGCGCTGGGTCTGTGGCAAGACTGCGAAGAAGACGGCATGGAATATCAACGTCAGCTACGCAAGGAGTGG
TAA