Detailed information of TA system
Overview
TA module
| Type | VIII | Classification (family/domain) | SdsR-RyeA/- |
| Location | 2029264..2029409 | Replicon | chromosome |
| Accession | NZ_CP065831 | ||
| Organism | Klebsiella pneumoniae strain KpC11 | ||
Toxin (RNA)
| Gene name | SdsR | ||
| Locus tag | - | ||
| Coordinates | 2029300..2029402 (+) |
Antitoxin (RNA)
| Gene name | RyeA | ||
| Locus tag | - | ||
| Coordinates | 2029264..2029409 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| I8N76_RS10020 | 2024394..2026454 | + | 2061 | WP_004151449.1 | oligopeptidase B | - |
| I8N76_RS10025 | 2026458..2027117 | - | 660 | WP_021440386.1 | exodeoxyribonuclease X | - |
| I8N76_RS10030 | 2027196..2027426 | - | 231 | WP_002911406.1 | DNA polymerase III subunit theta | - |
| I8N76_RS10035 | 2027539..2027913 | + | 375 | WP_004151448.1 | CopC domain-containing protein YobA | - |
| I8N76_RS10040 | 2027917..2028786 | + | 870 | WP_004189267.1 | copper homeostasis membrane protein CopD | - |
| I8N76_RS10045 | 2028803..2029141 | + | 339 | WP_002911404.1 | YebY family protein | - |
| - | 2029264..2029409 | - | 146 | - | - | Antitoxin |
| - | 2029300..2029402 | + | 103 | - | - | Toxin |
| I8N76_RS10050 | 2029777..2029920 | - | 144 | WP_002911398.1 | Ecr family regulatory small membrane protein | - |
| I8N76_RS10055 | 2030025..2030993 | - | 969 | WP_073971755.1 | VirK/YbjX family protein | - |
| I8N76_RS10060 | 2031150..2031803 | + | 654 | WP_009484457.1 | protein-serine/threonine phosphatase | - |
| I8N76_RS10065 | 2031800..2031991 | - | 192 | WP_002911395.1 | YebW family protein | - |
| I8N76_RS10070 | 2032089..2032328 | - | 240 | WP_002911393.1 | YebV family protein | - |
| I8N76_RS10075 | 2032444..2033877 | - | 1434 | WP_004148845.1 | 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 103 bp
>T183441 NZ_CP065831:2029300-2029402 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT
Antitoxin
Download Length: 146 bp
>AT183441 NZ_CP065831:c2029409-2029264 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT
