Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1837393..1837538 Replicon chromosome
Accession NZ_CP065825
Organism Klebsiella pneumoniae strain KpPF25

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1837429..1837531 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1837393..1837538 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I8N74_RS08965 1832523..1834583 + 2061 WP_004151449.1 oligopeptidase B -
I8N74_RS08970 1834587..1835246 - 660 WP_002911407.1 exodeoxyribonuclease X -
I8N74_RS08975 1835325..1835555 - 231 WP_002911406.1 DNA polymerase III subunit theta -
I8N74_RS08980 1835668..1836042 + 375 WP_004151448.1 CopC domain-containing protein YobA -
I8N74_RS08985 1836046..1836915 + 870 WP_009307538.1 copper homeostasis membrane protein CopD -
I8N74_RS08990 1836932..1837270 + 339 WP_009307539.1 YebY family protein -
- 1837393..1837538 - 146 - - Antitoxin
- 1837429..1837531 + 103 - - Toxin
I8N74_RS08995 1837907..1838050 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
I8N74_RS09000 1838155..1839123 - 969 WP_004151446.1 VirK/YbjX family protein -
I8N74_RS09005 1839280..1839933 + 654 WP_009307541.1 protein-serine/threonine phosphatase -
I8N74_RS09010 1839930..1840121 - 192 WP_002911395.1 YebW family protein -
I8N74_RS09015 1840219..1840458 - 240 WP_002911393.1 YebV family protein -
I8N74_RS09020 1840574..1842007 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T183420 NZ_CP065825:1837429-1837531 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT183420 NZ_CP065825:c1837538-1837393 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References