Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 2214151..2215361 Replicon chromosome
Accession NZ_CP065824
Organism Pseudomonas tolaasii strain Pt11

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag I7845_RS10010 Protein ID WP_177007777.1
Coordinates 2214151..2214723 (-) Length 191 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag I7845_RS10015 Protein ID WP_016971895.1
Coordinates 2214804..2215361 (-) Length 186 a.a.

Genomic Context

I7845_RS09985I7845_RS09990I7845_RS09995I7845_RS10000I7845_RS10005I7845_RS10030I7845_RS10010I7845_RS10015I7845_RS10020I7845_RS10025I7845_RS10035I7845_RS10040
Location: 2209432..2210397 (966 bp)
Type: Others
Protein ID: WP_016971901.1
Location: 2210390..2211163 (774 bp)
Type: Others
Protein ID: WP_017255374.1
Location: 2211181..2212104 (924 bp)
Type: Others
Protein ID: WP_026083165.1
Location: 2212117..2213700 (1584 bp)
Type: Others
Protein ID: WP_017255372.1
Location: 2213712..2214146 (435 bp)
Type: Others
Protein ID: WP_016971897.1
Location: 2217039..2217527 (489 bp)
Type: Others
Protein ID: WP_218820308.1
Location: 2214151..2214723 (573 bp)
Type: Toxin
Protein ID: WP_177007777.1
Location: 2214804..2215361 (558 bp)
Type: Antitoxin
Protein ID: WP_016971895.1
Location: 2215436..2215942 (507 bp)
Type: Others
Protein ID: WP_016971894.1
Location: 2215939..2216853 (915 bp)
Type: Others
Protein ID: WP_016971893.1
Location: 2217654..2218490 (837 bp)
Type: Others
Protein ID: WP_218820309.1
Location: 2218532..2219737 (1206 bp)
Type: Others
Protein ID: WP_016971890.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
I7845_RS09985 (I7845_09985)2209432..2210397+966WP_016971901.1amino acid ABC transporter permease-
I7845_RS09990 (I7845_09990)2210390..2211163+774WP_017255374.1amino acid ABC transporter ATP-binding protein-
I7845_RS09995 (I7845_09995)2211181..2212104+924WP_026083165.1ABC transporter substrate-binding protein-
I7845_RS10000 (I7845_10000)2212117..2213700+1584WP_017255372.1FAD-dependent oxidoreductase-
I7845_RS10005 (I7845_10005)2213712..2214146+435WP_016971897.1RidA family protein-
I7845_RS10010 (I7845_10010)2214151..2214723-573WP_177007777.1HD domain-containing proteinToxin
I7845_RS10015 (I7845_10015)2214804..2215361-558WP_016971895.1helix-turn-helix transcriptional regulatorAntitoxin
I7845_RS10020 (I7845_10020)2215436..2215942-507WP_016971894.1hypothetical protein-
I7845_RS10025 (I7845_10025)2215939..2216853-915WP_016971893.1hypothetical protein-
I7845_RS10030 (I7845_10030)2217039..2217527+489WP_218820308.1type VI secretion system tube protein Hcp-
I7845_RS10035 (I7845_10035)2217654..2218490-837WP_218820309.1HAD family acid phosphatase-
I7845_RS10040 (I7845_10040)2218532..2219737-1206WP_016971890.1DUF1835 domain-containing protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(9-186)

Antitoxin

Cro/C1-type helix-turn-helix domain

(12-46)


Sequences

Toxin        


Download         Length: 191 a.a.        Molecular weight: 21437.49 Da        Isoelectric Point: 4.9906

>T183413 WP_177007777.1 NZ_CP065824:c2214723-2214151 [Pseudomonas tolaasii]
MDIEKIKGRLDFLREAEKLKDVLRSAHTASGRTESTAEHSWRLCLMAMVFADELPGLDLLKILKMCVIHDLGEALHGDIP
AVSQAAFPNKGEQERNDLLVLAQPLDRPLRDEILALWDDYENAASPEARAVKAMDKLETLLQHTQGLNPPDFDYAFNLAY
GKKHTDAEPIFERLRHLIDKATQEKLDATP

Download         Length: 573 bp

>T183413 NZ_CP086981:c33159-32884 [Pseudosulfitobacter pseudonitzschiae]
GTGCCTGACCTTGAATGGAAGGCATTGGCGGTCGCGGACCTGATGGCGATTGTTGACTATATCTCGGATGACAATCCCGA
TGCCGCAATTTCCCTGATGGATGACATTCAAGACAAGGTGCTTGGCCTTCTGACGCATCCCAAATCCGGCCGCCCCGGTA
GGGTGAACGACACGCGAGAGCTGGTGATCCGGCCCAACTATATCGTCGTCTATGCTGAAAACACGGCGGCGGTCACCATT
CTGCGCGTTCTTCATGCGGTGCAGATGTGGCCCTGA

Antitoxin


Download         Length: 186 a.a.        Molecular weight: 20318.50 Da        Isoelectric Point: 9.6388

>AT183413 WP_016971895.1 NZ_CP065824:c2215361-2214804 [Pseudomonas tolaasii]
MPAPLLKPALPGIALRRWRTLHRVKQSHAAQMFKVTQSTISRWESGALAMDPDAHHQLERLLAARLEAAADHALARLVGE
SSRPVHLVCDLTHRLLACSPSRAAQFSRPLGELIGQSLWHFATPEIVQVEAALETAGWRETQAPPALEFMTGRNASSLVP
IHPGLCRWTRLVLSDGSAARLVETL

Download         Length: 558 bp

>AT183413 NZ_CP086981:c33445-33152 [Pseudosulfitobacter pseudonitzschiae]
ATGTCCGCTCAAACCTCGATGATTCATGTTCGTGTAGATGATCAGCTCAAGGCAAAGGCCACGGATGCCCTGTCCGGTGT
CGGCCTGACGTTGTCGGACGCCGTGCGCATCCTGCTGACCCGCGTGGCAGCAGAGGGTGGCTTGCCCGCAGGGTTGACGG
CAAATCCTGACGCCTACGATGCCTGGTTCCGCGCCAAGGTACAGGACGCATTGGCCGACGCAGCACCGGCCAAGCCGCAC
GATCAGGTGATGCGAGACGCGCGCGCCTTGATCGACGGCAAGCGCGGTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References