Detailed information of TA system TA183410

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RHH(antitoxin)
• Location: 961641..962182
• Replicon: chromosome
• Accession: NZ_CP065824
• Organism: Pseudomonas tolaasii strain Pt11

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: I7845_RS04205
• Protein ID: WP_026083149.1
• Coordinates: 961907..962182 (+)
• Length: 92 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A7Y8DPN2
• Locus tag: I7845_RS04200
• Protein ID: WP_016971600.1
• Coordinates: 961641..961907 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
I7845_RS04185 (I7845_04185)	957616..959901	-	2286	WP_218820025.1	TonB-dependent siderophore receptor	-
I7845_RS04190 (I7845_04190)	960108..960788	+	681	WP_016971602.1	Fe2+-dependent dioxygenase	-
I7845_RS04195 (I7845_04195)	960790..961575	+	786	WP_016971601.1	tetratricopeptide repeat protein	-
I7845_RS04200 (I7845_04200)	961641..961907	+	267	WP_016971600.1	ribbon-helix-helix domain-containing protein	Antitoxin
I7845_RS04205 (I7845_04205)	961907..962182	+	276	WP_026083149.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
I7845_RS04210 (I7845_04210)	962242..963405	-	1164	WP_080520058.1	type III PLP-dependent enzyme	-
I7845_RS04215 (I7845_04215)	963852..965009	-	1158	WP_016971597.1	ABC transporter ATP-binding protein	-
I7845_RS04220 (I7845_04220)	965006..965659	-	654	WP_016971596.1	ABC transporter permease	-
I7845_RS04225 (I7845_04225)	965669..966565	-	897	WP_177038132.1	glycine betaine ABC transporter substrate-binding protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (3-90)

Antitoxin

• Ribbon-helix-helix protein, CopG (8-44)

Sequences

Toxin

Protein

• Length: 92 a.a.
• Molecular weight: 10760.40 Da
• Isoelectric Point: 8.5620

>T183410 WP_026083149.1 NZ_CP065824:961907-962182 [Pseudomonas tolaasii]
MELKWTSKALSDLARLFDFLAVVNRMAAARTVQSLSQAPMSLVSNPRIGERVEEFEPRDVRRLLVGHYEIRYEIQESTVY
ILRLWHVREDR

Nucleotide

• Length: 276 bp

>T183410 NZ_CP086979:1833967-1834221 [Pseudosulfitobacter pseudonitzschiae]
ATGAACAGCAAGCAGCGGAAAACACTCAAGGCGATTTTCACCGATCCGGTGTCTGGCACAATCGAATGGGTCAGGATCGA
AAGTCTCCTTGTCGCGGCTGGCGCTGAAACCATCGAAGGCAACGGCTCGCGCGTTCGCTTTGTTAAGGACGGCGTGGTTG
GATCGTTCCACCGCCCGCACCCTGACAAAGAGGCAAAGCGCTATCAGGTTAGAGACGCCCGCGCCTTCCTAACGCAGATT
GGAGTAACGCCATGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9729.02 Da
• Isoelectric Point: 4.7539

>AT183410 WP_016971600.1 NZ_CP065824:961641-961907 [Pseudomonas tolaasii]
MGADTKVLTAHVPTALAQKVDQLAARMDRSRGWIVKQALADWVDMEEERSRLTREAMADVDAGRVIDQQAVQAWADSLST
DTPLPVPR

Nucleotide

• Length: 267 bp

>AT183410 NZ_CP086979:1834218-1834547 [Pseudosulfitobacter pseudonitzschiae]
ATGAGCACCATGACTTTCAAAGGCTATCAGGCCCGTGTGGAGTTCGATCCAGAGGACGAGATTTTCTTCGGTAGAATTGC
CGGGATAAACGATGTGGTTGGCTTCCACGGCGAAAGCGTTGCCGAGCTTAAGAGTGCCTTTCATGAAGCCGTTGATGATT
ATCTTGAAACCTGCAAGGCGGCTGGCAAGAAGCCCCAGAAGCCGTATTCTGGCAAGGTGATGTTTCGAGTCGCTCCTGAA
ACCCACAGGCGCATCGCAGTTGCAGCTGAACTTTCCGGCAAGAGCCTGAACCAGTGGGCAGAAGAAAAGCTAGAGGCTGC
TGCCCACTAA

Structures

Antitoxin

• AlphaFold DB: A0A7Y8DPN2