Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tsbAT/-
Location 179034..179784 Replicon chromosome
Accession NZ_CP065795
Organism Mammaliicoccus sciuri strain GDH8C110P

Toxin (Protein)


Gene name tsbT Uniprot ID -
Locus tag I7830_RS00880 Protein ID WP_198052458.1
Coordinates 179034..179141 (-) Length 36 a.a.

Antitoxin (Protein)


Gene name tsbA Uniprot ID -
Locus tag I7830_RS00885 Protein ID WP_198052205.1
Coordinates 179185..179784 (-) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I7830_RS00870 175877..177403 - 1527 WP_198052204.1 exopolyphosphatase -
I7830_RS00875 177493..178881 - 1389 WP_107577221.1 class II fumarate hydratase -
I7830_RS00880 179034..179141 - 108 WP_198052458.1 hypothetical protein Toxin
I7830_RS00885 179185..179784 - 600 WP_198052205.1 glucosamine-6-phosphate isomerase Antitoxin
I7830_RS00890 179833..180984 - 1152 WP_198052206.1 N-acetylglucosamine-6-phosphate deacetylase -
I7830_RS00895 181071..181211 + 141 WP_162841915.1 hypothetical protein -
I7830_RS00900 181246..181719 - 474 WP_025904798.1 tRNA (uridine(34)/cytosine(34)/5- carboxymethylaminomethyluridine(34)-2'-O)- methyltransferase TrmL -
I7830_RS00905 181723..182850 - 1128 WP_037589731.1 tRNA epoxyqueuosine(34) reductase QueG -
I7830_RS00910 183220..183981 - 762 WP_198052207.1 acetylglutamate kinase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Glucosamine-6-phosphate isomerase

(134-195)


Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4130.47 Da        Isoelectric Point: 3.8954

>T183403 WP_198052458.1 NZ_CP065795:c179141-179034 [Mammaliicoccus sciuri]
MVQDLEDVKELGKEMEQISEQNDEAFEEKKSEKES

Download         Length: 108 bp

>T183403 NZ_CP086972:81677-81952 [Pseudosulfitobacter pseudonitzschiae]
GTGCCTGACCTTGAATGGAAGGCATTGGCGGTCGCGGACCTGATGGCGATTGTTGACTATATCTCGGATGACAATCCCGA
TGCCGCAATTTCCCTGATGGATGACATTCAAGACAAGGTGCTTGGCCTTCTGACGCATCCCAAATCCGGCCGCCCCGGTA
GGGTGAACGACACGCGAGAGCTGGTGATCCGGCCCAACTATATCGTCGTCTATGCTGAAAACACGGCGGCGGTCACCATT
CTGCGCGTTCTTCATGCGGTGCAGATGTGGCCCTGA

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22305.14 Da        Isoelectric Point: 4.7525

>AT183403 WP_198052205.1 NZ_CP065795:c179784-179185 [Mammaliicoccus sciuri]
MALNFKVFETKEIAARYAADVVRKQFNSDSTSVVGLHLEAEQTSFFDELLDDVKKNPVNFSQIHILDFDGNEDYYTELGV
PAKQVLKTDVGSDVEAFIKEKVNTDKKKNKLMLDVVTLTEDSRTGLDYDQAIHPAREVIVLVTGKEKAKAVSQLYQEPAN
GSVESAKLKQHRMVTVVLDNEAAQGLPEDVRSYFSIQFS

Download         Length: 600 bp

>AT183403 NZ_CP086972:81391-81684 [Pseudosulfitobacter pseudonitzschiae]
ATGTCCGCTCAAACCTCGATGATTCATGTTCGTGTAGATGATCAGCTCAAGGCAAAGGCCACGGATGCCCTGTCCGGTGT
CGGCCTGACGTTGTCGGACGCCGTGCGCATCCTGCTGACCCGCGTGGCAGCAGAGGGTGGCTTGCCCGCAGGGTTGACGG
CAAATCCTGACGCCTACGATGCCTGGTTCCGCGCCAAGGTACAGGACGCATTGGCCGACGCAGCACCGGCCAAGCCGCAC
GATCAGGTGATGCGAGACGCGCGCGCCTTGATCGACGGCAAGCGCGGTGCCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References