Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) yxiD-yxxD/-
Location 3491307..3492095 Replicon chromosome
Accession NZ_CP065790
Organism Bacillus velezensis strain LBUM1082

Toxin (Protein)


Gene name yxiD Uniprot ID -
Locus tag I8N72_RS17190 Protein ID WP_079891856.1
Coordinates 3491754..3492095 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name yxxD Uniprot ID -
Locus tag I8N72_RS17185 Protein ID WP_015387595.1
Coordinates 3491307..3491744 (-) Length 146 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
I8N72_RS17150 3486834..3487370 + 537 WP_014305969.1 chromate resistance efflux protein ChrA -
I8N72_RS17155 3487397..3487615 - 219 WP_015387600.1 hypothetical protein -
I8N72_RS17160 3487612..3488157 - 546 WP_015387599.1 flavodoxin family protein -
I8N72_RS17165 3488280..3489161 + 882 WP_015387598.1 LysR family transcriptional regulator -
I8N72_RS17170 3489248..3489964 - 717 WP_015387597.1 endonuclease V -
I8N72_RS17175 3490004..3490504 - 501 WP_015387596.1 hypothetical protein -
I8N72_RS17180 3490696..3491136 - 441 Protein_3321 SMI1/KNR4 family protein -
I8N72_RS17185 3491307..3491744 - 438 WP_015387595.1 SMI1/KNR4 family protein Antitoxin
I8N72_RS17190 3491754..3492095 - 342 WP_079891856.1 HNH endonuclease Toxin
I8N72_RS17195 3492714..3493052 - 339 Protein_3324 transposase -
I8N72_RS17200 3493691..3494156 - 466 Protein_3325 DUF2004 domain-containing protein -
I8N72_RS17205 3494158..3494683 - 526 Protein_3326 HNH endonuclease -
I8N72_RS17210 3494854..3495159 - 306 WP_003151282.1 hypothetical protein -
I8N72_RS17215 3495176..3496921 - 1746 WP_015387593.1 ribonuclease YeeF family protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin


No domain identified.



Sequences


Toxin        


Download         Length: 114 a.a.        Molecular weight: 13224.74 Da        Isoelectric Point: 9.6942

>T183397 WP_079891856.1 NZ_CP065790:c3492095-3491754 [Bacillus velezensis]
IKEALRNNNYEKLTPKETAKHRSKFTSSLKDRLIAEWEEKTNQKWPRYTEEVFDKHGEVARSIGQPYDAHHIIENNFGGP
HEWWNIHPAKYPDEHQAGIHGKGAPSGKLFPRR

Download         Length: 342 bp

>T183397 NZ_CP086966:104015-104281 [Pseudosulfitobacter pseudonitzschiae]
GTGAAGTTGGTTTTTTCCGATCAGGCTTGGGAAGACTATCAGTACTGGGTCAACACCAACGACAAGGTACGTGACCGGAT
CAACGAGCTGATCAAGCAGTGCAGGCGGACCCCTTTCAAAGGAACCGGCAAGCCGGAACCTTTGAAGGGCGATCTGACCG
GCTGGTGGTCACGGCGGATTTCTCAGGAAGATCGAATGGTCTACCGGGTTAGTGGAACTGGCGACGGCCAAAGCCTAGAG
ATTGCACAACTGCGGTTTCATTACTGA

Antitoxin


Download         Length: 146 a.a.        Molecular weight: 16992.02 Da        Isoelectric Point: 3.8929

>AT183397 WP_015387595.1 NZ_CP065790:c3491744-3491307 [Bacillus velezensis]
MAEFEFINHLENKTYKVPEEDILKAEQRMNVDIPNDLKQLYLEVGYGFIKGESDNAINRILGPGAVADIRLREGIFEFDP
DLGELYDDENKLIFFEVNEGVYISIDLRLANNPIFYFDTQIAESLEDFFKKFLNDNEYYIDLIED

Download         Length: 438 bp

>AT183397 NZ_CP086966:103767-104018 [Pseudosulfitobacter pseudonitzschiae]
ATGGATGTTATGACCTATTCAGACGCACGAGCTCAACTGAAGGGCGTCATGGATCGAGCGATCCACGACAAGCAAGAAGT
TGTTGTGACGCGCAAAAAAGGAGAGTCCGTCGTGGTCGTATCCTTGGAAACCTGGAACGCCGTAAATGAGACGCTGCACC
TCCTGTCCACACCAAAAAACGCATCCCGCTTGCGCGCGTCGATCGCGCAACTCGATGCTGGAACTGGCGAAGTGCGTGAG
CTGACCGAGTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References